Interesting facts
Interesting Facts about N-(4-ethylphenyl)-2,2,2-trifluoro-acetamide
N-(4-ethylphenyl)-2,2,2-trifluoro-acetamide is a fascinating compound that showcases the intricate relationship between functional groups and their chemical behavior. Here are some notable aspects of this compound:
- Functional Group Diversity: This compound features an amide functional group, which is known for its ability to stabilize molecular structures through resonance. The presence of the trifluoroacetamide group enhances its polarity and solubility characteristics, making it an interesting subject for polar solvent interactions.
- Fluorine Effects: The trifluoro group significantly influences the compound's reactivity and physical properties. The electronegativity of fluorine increases molecular interactions as well as alters the acidity and basicity of the amide group, which can have profound implications in synthetic chemistry.
- Biological Relevance: Compounds with such structural motifs often exhibit biological activity. They can serve as valuable scaffolds in the design of pharmaceutical agents. The ethylphenyl moiety might provide lipophilicity, enhancing the compound’s potential for cross-cellular permeability.
- Applications in Organofluorine Chemistry: As a member of the organofluorine family, this compound can be significant in medicinal chemistry. Compounds with fluorinated groups have unique properties such as increased metabolic stability and modified bioactivity, making them key players in drug development.
In summary, N-(4-ethylphenyl)-2,2,2-trifluoro-acetamide is more than just a chemical compound; it reflects the beauty of molecular design and the complexities of chemical behavior. Its structural features provide chemists with numerous avenues for exploration and potential applications in various fields.
Synonyms
N-(4-ethylphenyl)-2,2,2-trifluoroacetamide
14618-46-3
Acetamide, N-(4-ethylphenyl)-2,2,2-trifluoro-
ACETANILIDE, 4'-ETHYL-2,2,2-TRIFLUORO-
BRN 2725538
4'-Ethyl-2,2,2-trifluoroacetanilide
4-Ethylaniline, TFA
CBMicro_031020
SCHEMBL17845228
DTXSID50163290
STK412308
AKOS003238303
BIM-0030799.P001
ST45244258
SR-01000212603
SR-01000212603-1
Solubility of N-(4-ethylphenyl)-2,2,2-trifluoro-acetamide
N-(4-ethylphenyl)-2,2,2-trifluoro-acetamide, a compound with distinctive chemical properties, exhibits nuanced solubility behavior influenced by its molecular structure. Understanding its solubility is crucial for various applications in chemistry and related fields.
Solubility Characteristics
The solubility of this compound can be summarized as follows:
In summary, while N-(4-ethylphenyl)-2,2,2-trifluoro-acetamide shows good solubility in a range of organic solvents, it may present challenges when it comes to dissolving in polar environments due to its specific structural characteristics. Thus, “understanding solubility is key,” providing insights into the compound’s behavior and potential applications in synthesis and formulation.