Interesting facts
N-(4-fluoro-9H-fluoren-2-yl)acetamide: Fascinating Facts
N-(4-fluoro-9H-fluoren-2-yl)acetamide is an intriguing compound that catches the attention of chemists for several reasons:
- Fluorine in Action: The presence of a fluorine atom is notable. Fluorine is known for its high electronegativity, which can greatly influence the reactivity and stability of organic compounds.
- Fluorinated Aromatics: The compound boasts a fluorinated aromatic ring structure, which can enhance its properties in medicinal chemistry. Aromatic compounds with fluorine often exhibit increased metabolic stability.
- Versatile Applications: This compound is studied for possible applications in drug development. Aromatic amides are vital in creating pharmaceuticals and can participate in various biological activities, serving as potential therapeutic agents.
- Structural Insights: The unique structure of N-(4-fluoro-9H-fluoren-2-yl)acetamide allows it to engage in diverse non-covalent interactions, such as hydrogen bonding and π-π stacking, which are critical in molecular recognition processes.
- Synthetic Pathways: The synthesis of this compound can be achieved through various methods, often involving nucleophilic substitution reactions. This provides a practical route for the introduction of the acetamide functional group to the fluorenyl moiety.
As chemists continue to explore the properties and potential applications of N-(4-fluoro-9H-fluoren-2-yl)acetamide, the compound stands out as a remarkable subject of study, bridging the gap between fundamental chemistry and real-world applications.
Synonyms
4-Fluoro-2-faa
2823-91-8
N-(4-fluoro-9H-fluoren-2-yl)acetamide
4-Fluoro-2-acetylaminofluorene
ACETAMIDE, N-(4-FLUOROFLUOREN-2-YL)-
N-(4-Fluorofluoren-2-yl)acetamide
Acetamide, N-(4-fluoro-9H-fluoren-2-yl)-
NSC 55544
BRN 2811028
NSC55544
Acetamide,N-(4-fluoro-9H-fluoren-2-yl)-
CHEMBL86252
DTXSID70182483
NSC-55544
WLN: L B656 HHJ CF EMV1
DS-009561
Solubility of N-(4-fluoro-9H-fluoren-2-yl)acetamide
N-(4-fluoro-9H-fluoren-2-yl)acetamide, with its intriguing structure, displays interesting solubility characteristics that are important for its potential applications. The solubility of this compound can be influenced by various factors such as:
Given the structural features, one might expect that solubility increases in organic solvents, particularly those that can engage in hydrogen bonding. It's also worth noting that the temperature of the solvent can affect solubility; typically, solubility increases with temperature for many organic compounds.
In summary, while N-(4-fluoro-9H-fluoren-2-yl)acetamide may show limited solubility in water, it exhibits favorable solubility in a variety of organic solvents, paving the way for its effective utilization in various chemical applications.