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USP-7 Inhibitor II

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Identification
Molecular formula
C15H11FN2
CAS number
1032900-25-6
IUPAC name
N-(4-fluorophenyl)-1-(1H-indol-3-yl)methanimine
State
State

At room temperature, this compound is typically in a solid state.

Melting point (Celsius)
187.50
Melting point (Kelvin)
460.65
Boiling point (Celsius)
518.49
Boiling point (Kelvin)
791.64
General information
Molecular weight
248.26g/mol
Molar mass
248.2870g/mol
Density
1.2928g/cm3
Appearence

N-(4-fluorophenyl)-1-(1H-indol-3-yl)methanimine is typically observed as a crystalline solid under room temperature and pressure.

Comment on solubility

Solubility of N-(4-fluorophenyl)-1-(1H-indol-3-yl)methanimine

N-(4-fluorophenyl)-1-(1H-indol-3-yl)methanimine, a compound known for its intriguing chemical structure, exhibits particular solubility characteristics that are important for its applications in research and development.

Generally, the solubility of this compound can be influenced by several factors:

  • Polarity: The presence of the indole and fluorophenyl groups contributes to its overall polarity, which affects its solubility in various solvents.
  • Solvent Choice: This compound is likely to be more soluble in organic solvents, such as dichloromethane or ethanol, than in polar protic solvents like water.
  • Temperature Effects: Increasing temperature typically enhances solubility for many organic compounds. Hence, conducting solubility tests at varying temperatures could yield insightful data.
  • pH Dependence: The solubility of this compound may change with pH levels, as protonation or deprotonation can alter its solubility.

Researchers may observe that:

  1. In aqueous solutions, the solubility might be limited, which is common for many organic compounds.
  2. In nonpolar solvents, solubility may be markedly lower, showcasing the need for selecting appropriate solvent systems for practical applications.

In conclusion, the solubility of N-(4-fluorophenyl)-1-(1H-indol-3-yl)methanimine is a complex interplay of various factors that can significantly impact its usability in chemical and pharmaceutical contexts. Understanding these nuances is crucial for effective experimentation and application.

Interesting facts

Interesting Facts about N-(4-fluorophenyl)-1-(1H-indol-3-yl)methanimine

N-(4-fluorophenyl)-1-(1H-indol-3-yl)methanimine is a fascinating compound that showcases the intricate world of organic chemistry and its applications. Here are some noteworthy aspects of this compound:

  • Pharmaceutical Relevancy: This compound contains both the indole and fluorophenyl moieties, which are significant in drug discovery. Indole derivatives are often used in medicinal chemistry due to their biological activity and role in various therapeutic areas.
  • Fluorine's Influence: The presence of the fluorine atom can enhance the pharmacokinetic properties of the compound. It affects factors such as lipophilicity, stability, and binding affinity, making fluorinated compounds valuable in medicinal chemistry.
  • Indole Structure: The indole ring is an important structural motif found in many natural products and pharmaceuticals. Its aromatic nature allows for strong interactions with biological targets, including enzymes and receptors.
  • Research Applications: Compounds like N-(4-fluorophenyl)-1-(1H-indol-3-yl)methanimine are regularly explored in research settings for their potential roles in treating various diseases, including cancer, by targeting specific biological pathways.

As a compound with both indole and fluorobenzene substructures, N-(4-fluorophenyl)-1-(1H-indol-3-yl)methanimine represents the fusion of complex organic architectures that hold promise for novel therapeutic development. Its continued study could unlock new horizons in drug design and molecular therapy.

Synonyms
22394-32-7
4-Fluoro-N-(1H-indol-3-ylmethylene)benzenamine
RefChem:292873
CHEMBL1957877
3-(N-p-Fluorophenylformimidoyl)indole
BRN 1462246
INDOLE, 3-(N-(p-FLUOROPHENYL)FORMIMIDOYL)-
DTXSID501249751
BDBM50365892
STL377688
AKOS024267101
3-[(4-Fluorophenylimino)Methyl]Indole
4-fluoro-N-(1H-indol-3-ylmethylene)aniline
AG-205/32387020
4-fluoro-N-[(E)-1H-indol-3-ylmethylidene]aniline