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4-fluoro-N-methyl-N-nitrosoaniline

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Identification
Molecular formula
C7H7FN2O
CAS number
450-91-9
IUPAC name
N-(4-fluorophenyl)-N-methyl-nitrous amide
State
State

At room temperature, 4-fluoro-N-methyl-N-nitrosoaniline is typically found in a solid state.

Melting point (Celsius)
84.00
Melting point (Kelvin)
357.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
154.15g/mol
Molar mass
154.1450g/mol
Density
1.1675g/cm3
Appearence

4-Fluoro-N-methyl-N-nitrosoaniline is typically a yellow to brownish solid. It is crystalline in nature and may have a distinct chemical odor.

Comment on solubility

Solubility of N-(4-fluorophenyl)-N-methyl-nitrous amide

N-(4-fluorophenyl)-N-methyl-nitrous amide, with the chemical formula C8H9F1N2O, exhibits interesting solubility characteristics that are influenced by its structural components.

In general, the solubility of this compound can be summarized as follows:

  • Polar Nature: Due to the presence of the nitrous amide functional group, this compound tends to have polar characteristics, which can enhance its solubility in polar solvents.
  • Solvent Compatibility: It is likely soluble in solvents such as water, methanol, and ethanol, where polar interactions can be maximized.
  • Limited Solubility in Non-polar Solvents: Conversely, N-(4-fluorophenyl)-N-methyl-nitrous amide may exhibit low solubility in non-polar solvents like hexane or benzene due to a lack of favorable interactions.

To conclude, as with many organic compounds, the solubility of N-(4-fluorophenyl)-N-methyl-nitrous amide is primarily dictated by its structural features and the solvent's properties. Its polar nature fosters solubility in polar media while limiting its dissolvability in non-polar environments. This dual behavior is a key aspect to consider in practical applications and further research.

Interesting facts

Interesting Facts about N-(4-fluorophenyl)-N-methyl-nitrous amide

N-(4-fluorophenyl)-N-methyl-nitrous amide is a fascinating compound that finds its relevance in various fields of chemistry and industry. Here are some compelling details that showcase its significance and unique characteristics:

  • Origin: This compound represents a class of nitrous amides, which are notable for their role in organic synthesis. They are essential in designing and preparing other biologically active molecules through functional group transformations.
  • Fluorine's Role: The presence of the 4-fluorophenyl group is particularly interesting as fluorine is known to alter the properties of organic compounds significantly. This can lead to enhanced biological activity or modifications in reactivity, making it a popular choice in medicinal chemistry.
  • Applications: N-(4-fluorophenyl)-N-methyl-nitrous amide serves pivotal functions in the development of pharmaceuticals. Its derivatives may be researched for their potential use in treatments, especially in areas targeting metabolic diseases.
  • Synthetic Utility: As a nitrous amide, this compound can be employed in various synthetic pathways. Its versatility allows chemists to create a wide array of conjugated systems, which are crucial in the advancement of complex molecules.
  • Stability and Safety: Understanding the stability of nitrous amides, including N-(4-fluorophenyl)-N-methyl-nitrous amide, is vital for ensuring safe handling in laboratories. Its kinetic properties can affect how it behaves under different conditions.
  • Research Potential: Ongoing research exploring the structure-activity relationship (SAR) of compounds similar to N-(4-fluorophenyl)-N-methyl-nitrous amide could lead to significant breakthroughs in drug design and development.

In summary, N-(4-fluorophenyl)-N-methyl-nitrous amide is more than just a chemical formula; it opens up a realm of possibilities in organic synthesis and pharmaceuticals. The study of such compounds not only enhances our understanding of chemical interactions but also propels innovation in medical therapies.

Synonyms
N-Nitroso-N-methyl-4-fluoroaniline
937-25-7
p-Fluoro-N-methyl-N-nitrosoaniline
N-(4-fluorophenyl)-N-methylnitrous amide
BRN 1841690
ANILINE, p-FLUORO-N-METHYL-N-NITROSO-
DTXSID9021001
4-Fluoro-N-methyl-N-nitrosobenzenamine
p-FNMA
DTXCID501001
881-074-9
4-fluoro-N-methyl-N-nitrosoaniline
9LSX9S4XBW
UNII-9LSX9S4XBW
Methyl(4-fluorophenyl)nitrosamine
AKOS006272804
Nitroso-N-methyl-4-fluoroaniline, N-
Benzenamine, 4-fluoro-N-methyl-N-nitroso-
F81208
EN300-7691313