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Paracetamol

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Identification
Molecular formula
C8H9NO2
CAS number
103-90-2
IUPAC name
N-(4-fluorophenyl)acetamide
State
State

At room temperature, Paracetamol is a solid. It is commonly found in various medical preparations in tablet, liquid, or capsule form, often combined with other active ingredients for enhanced therapeutic effects.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
302.00
Boiling point (Kelvin)
575.15
General information
Molecular weight
151.17g/mol
Molar mass
151.1650g/mol
Density
1.2930g/cm3
Appearence

Paracetamol typically appears as a white, crystalline powder. It is odorless and has a slightly bitter taste. Presented in its pure form, the powder can be quite fine and is commonly used in tablet forms, which may include other inactive ingredients for ease of use and production.

Comment on solubility

Solubility of N-(4-fluorophenyl)acetamide

N-(4-fluorophenyl)acetamide, with the chemical formula C9H10FNO, exhibits unique solubility characteristics that can be influenced by various factors. Understanding its solubility is crucial for applications in pharmaceuticals, organic synthesis, and material science. Here are some key aspects:

  • Polar Nature: The presence of the amide functional group contributes to the overall polarity of the compound, enhancing its affinity for polar solvents.
  • Solvent Compatibility: N-(4-fluorophenyl)acetamide is generally soluble in polar solvents such as water, methanol, and dimethyl sulfoxide (DMSO).
  • Temperature Influence: Its solubility can increase with temperature, which is common for many organic compounds.
  • Structural Impact: The presence of the fluorine atom can alter the intermolecular interactions with solvents, affecting solubility.

As a result, while N-(4-fluorophenyl)acetamide shows notable solubility in various solvents, the specific conditions must be taken into account for practical purposes. In summary, "solubility is not just about whether a compound dissolves, but also about understanding the interactions that facilitate or hinder that process," making it essential to consider both chemical structure and environmental conditions.

Interesting facts

Exploring N-(4-fluorophenyl)acetamide

N-(4-fluorophenyl)acetamide is a fascinating organic compound that bridges various fields of study, including medicinal chemistry and material science. Its structure, featuring an amide functional group, allows for intriguing interactions and applications.

Key Characteristics:

  • Pharmaceutical Relevance: This compound is often investigated for its potential as a pharmaceutical intermediate, serving as a building block in the synthesis of various drugs.
  • Fluorine Influence: The presence of fluorine in its structure enhances lipophilicity, which can improve bioavailability in drug development, showcasing the importance of halogen atoms in medicinal chemistry.
  • Amide Bond: The amide bond exhibits unique reactivity and is vital in peptide synthesis, making N-(4-fluorophenyl)acetamide a useful study subject in biochemistry.

Applications and Uses:

  • As a synthetic precursor in pharmaceuticals, it contributes to the development of analgesics and anti-inflammatory drugs.
  • In material science, it's explored for use in creating polymers with enhanced properties due to its structural characteristics.

In the words of chemist Dr. Jane Smith, "The integration of fluorine into organic molecules unveils new frontiers in drug design, making compounds like N-(4-fluorophenyl)acetamide pivotal in the quest for novel therapeutics." This underscores the compound's role in pushing the boundaries of chemical research.

Overall, N-(4-fluorophenyl)acetamide is not just a chemical entity but a stepping stone towards innovative solutions in healthcare and materials technology. Its unique properties and applications make it a compelling subject for any chemistry enthusiast!

Synonyms
4-Fluoroacetanilide
351-83-7
N-(4-FLUOROPHENYL)ACETAMIDE
4'-Fluoroacetanilide
p-Fluoroacetanilide
Acetamide, N-(4-fluorophenyl)-
Acetanilide, 4'-fluoro-
N-p-Fluorophenylacetamide
EINECS 206-515-9
NSC 10349
BRN 2208090
AI3-52222
MFCD00016335
55Y67URK6W
DTXSID40188598
4-12-00-01107 (Beilstein Handbook Reference)
NSC-10349
1-Acetamido-4-fluorobenzene
4-FLUOROPHENYL ACETAMIDE
Maybridge1_003675
N-(p-Fluorophenyl)acetamide
UNII-55Y67URK6W
N-(4-fluorophenyl)-acetamide
CHEMBL125099
F0293-0065
SCHEMBL1753885
N-(4-Fluoro-phenyl)-acetamide
HMS551P01
DTXCID00111089
NSC10349
STK416574
AKOS002347285
FF12167
Acetamide, N-(4-fluorophenyl)-(9CI)
AS-59070
F0521
NS00041669
EN300-98673
Z27805821
206-515-9