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Dabigatran

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Identification
Molecular formula
C34H41N7O5
CAS number
211915-06-9
IUPAC name
N-[4-guanidino-1-[(4-nitrophenyl)carbamoyl]butyl]benzamide
State
State

At room temperature, Dabigatran is in a solid state. It is most commonly found in its crystalline powder form.

Melting point (Celsius)
161.00
Melting point (Kelvin)
434.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
627.75g/mol
Molar mass
627.6930g/mol
Density
1.4874g/cm3
Appearence

Dabigatran typically presents as a white to yellowish powder. It is known for its crystalline form and slightly hygroscopic nature.

Comment on solubility

Solubility of N-[4-guanidino-1-[(4-nitrophenyl)carbamoyl]butyl]benzamide

N-[4-guanidino-1-[(4-nitrophenyl)carbamoyl]butyl]benzamide is a compound with unique solubility characteristics that are influenced by its molecular structure and functional groups. Here are some key points regarding its solubility:

  • Polar Functional Groups: The presence of polar groups such as guanidine and amide enhances the compound's interaction with polar solvents, particularly water.
  • Solvent Compatibility: This compound may show higher solubility in dimethyl sulfoxide (DMSO) and ethanol, which can solvate its polar nature effectively.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to functional groups can lead to increased solubility in polar solvents.
  • Temperature Impact: Solubility may vary with temperature, as is common for many organic compounds, often increasing with higher temperatures.

In summary, the solubility of N-[4-guanidino-1-[(4-nitrophenyl)carbamoyl]butyl]benzamide is primarily governed by its functional groups and polarity. As noted, this compound may exhibit significant solubility in polar solvents due to its structure, making it an interesting candidate for various applications in solution chemistry.

Interesting facts

Interesting Facts about N-[4-guanidino-1-[(4-nitrophenyl)carbamoyl]butyl]benzamide

This chemical compound presents a fascinating study case due to its unique structural features and potential applications. Here are some noteworthy aspects:

  • Basic Structure: The compound consists of a benzamide core, which is further functionalized with a guanidine and a nitrophenyl moiety. This combination allows for interesting interactions within biological systems.
  • Biological Relevance: Compounds like this one are often studied for their potential roles as therapeutics in various diseases. The guanidino group can participate in hydrogen bonding and ionic interactions, enhancing biological activity.
  • Vibrant Chemistry: The nitrophenyl group is known for its electron-withdrawing properties, which could influence the reactivity of the compound, making it valuable in synthesis and drug design.
  • Research Applications: There’s growing interest in the use of such compounds in the field of medicinal chemistry, particularly in developing active agents for anti-cancer or anti-inflammatory purposes.

As a student or researcher, one might say, "The complexity of N-[4-guanidino-1-[(4-nitrophenyl)carbamoyl]butyl]benzamide reflects the intricate dance of molecular interactions that elucidate the science of life itself." Studying compounds like this not only sheds light on their pharmacological properties but also meets the curiosity of scientists regarding the fundamental principles of chemistry at play.

Synonyms
BENZOYLARGININE NITROANILIDE
EINECS 213-010-7
(1)-N-(4-((Aminoiminomethyl)amino)-1-(((4-nitrophenyl)amino)carbonyl)butyl)benzamide
Benzamide, N-(4-((aminoiminomethyl)amino)-1-(((4-nitrophenyl)amino)carbonyl)butyl)-, (+-)-
Nitroanilide, Benzoylarginine
N Benzoylarginyl 4 nitroanilide
N-Benzoylarginyl-4-nitroanilide
N Benzoylarginine 4 nitroanilide
N-Benzoylarginine-4-nitroanilide
(1)N(4((Aminoiminomethyl)amino)1(((4nitrophenyl)amino)carbonyl)butyl)benzamide
Benzamide, N(4((aminoiminomethyl)amino)1(((4nitrophenyl)amino)carbonyl)butyl), (+)
911-76-2
SCHEMBL701212
CHEMBL1907476
SCHEMBL20471420
DTXSID40919960
n-benzoyl-dl-arginine-4-nitroanilide
AKOS024370373
PD150663
NS00041612
SR-01000645497-1
N-(4-([Amino(imino)methyl]amino)-1-[(4-nitroanilino)carbonyl]butyl)benzamide #
N-[5-Carbamimidamido-1-(4-nitroanilino)-1-oxopentan-2-yl]benzenecarboximidic acid
Benzamide, N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]-, (.+/-.)-