Skip to main content

Ibuprofen

ADVERTISEMENT
Identification
Molecular formula
C13H18O2
CAS number
15687-27-1
IUPAC name
N-(4-hydroxyphenyl)-3-isopropyl-2-methoxy-6-methyl-benzamide
State
State
Ibuprofen exists as a solid at room temperature. In its formulated product forms, it is presented as tablets, caplets, or liquid suspensions.
Melting point (Celsius)
76.00
Melting point (Kelvin)
349.00
Boiling point (Celsius)
249.00
Boiling point (Kelvin)
522.00
General information
Molecular weight
206.28g/mol
Molar mass
206.2820g/mol
Density
1.0300g/cm3
Appearence

Ibuprofen appears as a white crystalline powder. It is often used in its tablet form, which may vary in color depending on the excipients used in its production. The pure form is typically colorless and can also appear as white granules. It is characterized by the absence of odor.

Comment on solubility

Solubility of N-(4-hydroxyphenyl)-3-isopropyl-2-methoxy-6-methyl-benzamide

N-(4-hydroxyphenyl)-3-isopropyl-2-methoxy-6-methyl-benzamide showcases interesting solubility characteristics due to its complex molecular structure. The solubility of this compound can be influenced by various factors:

  • Polarity: The presence of both hydrophobic (isopropyl and methyl groups) and hydrophilic (hydroxy and methoxy groups) functional groups suggests a moderate level of polarity.
  • Solvent Nature: This compound is likely to exhibit better solubility in organic solvents, such as ethanol, methanol, and DMSO, due to its non-polar substituents.
  • Temperature Effects: As with many organic compounds, increasing the temperature will generally enhance solubility. Therefore, dissolving this compound at raised temperatures can aid in achieving a more concentrated solution.

In summary, while N-(4-hydroxyphenyl)-3-isopropyl-2-methoxy-6-methyl-benzamide shows promising solubility properties in organic solvents, its overall behavior in various mediums requires careful consideration to optimize solubility based on the intended application. As always, when experimenting with solubility characteristics, testing in controlled environments is essential for accurate results.

Interesting facts

Interesting Facts about N-(4-hydroxyphenyl)-3-isopropyl-2-methoxy-6-methyl-benzamide

This intriguing compound belongs to a class of organic molecules known as benzamides, which are characterized by the presence of a benzene ring attached to a carboxamide group. The specific structure of N-(4-hydroxyphenyl)-3-isopropyl-2-methoxy-6-methyl-benzamide adds a fascinating layer to its chemistry. Here are some key points worth noting:

  • Functional Versatility: The presence of various functional groups in this compound, such as the hydroxy (-OH) and methoxy (-OCH3) groups, can significantly influence its reactivity and interactions in biological systems.
  • Biological Activity: Compounds similar to this one have been studied for their potential pharmaceutical applications, particularly as anti-inflammatory and analgesic agents. This opens up avenues for research in medicinal chemistry.
  • Synthesis Approaches: The synthesis of benzamides can be accomplished through multiple methods, including the reaction of amines with acid chlorides or by using coupling reactions that link aromatic compounds together.
  • Structural Insights: The spatial arrangement of the isopropyl and methyl groups within the compound can lead to intriguing steric effects, which may impact how the compound interacts with other molecular targets in a biological context.
  • Research Relevance: Compounds with similar structures are often examined for their roles in various biological processes, making them a significant subject in both organic and medicinal chemistry.

As a student or scientist, to quote a famous chemist, “Chemistry is the study of matter, but I prefer to see it as the study of change.” Understanding the changes and interactions involving N-(4-hydroxyphenyl)-3-isopropyl-2-methoxy-6-methyl-benzamide could lead to exciting advancements in drug development and material science.

Synonyms
BRN 2816352
p-CYMENE-2-CARBOXANILIDE, 4'-HYDROXY-3-METHOXY-
4'-Hydroxy-3-methoxy-p-cymene-2-carboxanilide
3894-03-9
DTXSID70192229
DTXCID30114720