N-(4-Iodophenyl)-1-methylsulfanyl-methanimidothioic acid

Identification

Molecular formula

C₈H₈INOS₂

CAS number

42469-26-5

IUPAC name

N-(4-iodophenyl)-1-methylsulfanyl-methanimidothioic acid

State

At room temperature, N-(4-Iodophenyl)-1-methylsulfanyl-methanimidothioic acid is typically found in a solid state, taking the form of crystalline powder or granules.

Melting point (Celsius)

185.00

Melting point (Kelvin)

458.00

Boiling point (Celsius)

450.00

Boiling point (Kelvin)

723.00

General information

Molecular weight

357.22g/mol

Molar mass

357.2210g/mol

Density

2.1840g/cm³

Appearence

N-(4-Iodophenyl)-1-methylsulfanyl-methanimidothioic acid appears in the form of a crystalline solid with a color ranging from white to pale yellow. The crystals are typically odorless.

Comment on solubility

Solubility of N-(4-iodophenyl)-1-methylsulfanyl-methanimidothioic acid

N-(4-iodophenyl)-1-methylsulfanyl-methanimidothioic acid is a compound that exhibits unique solubility characteristics due to its specific functional groups. Understanding the solubility behavior of this compound can be broken down as follows:

Polarity: The presence of the iodophenyl group contributes to its overall polarity, which can enhance solubility in polar solvents.
Solvent Interaction: This compound is likely to be more soluble in solvents such as dimethyl sulfoxide (DMSO) or methanol due to their ability to interact with the polar and ionic parts of the molecule.
Hydrogen Bonding: The methanimidothioic acid moiety may introduce opportunities for hydrogen bonding, which can further facilitate solubility in aqueous environments.

However, solubility may be limited in non-polar solvents due to the hydrophobic nature of certain parts of the molecule, particularly when it comes to larger alkyl groups. Therefore, predicting solubility requires consideration of both the molecular structure and the solvent characteristics.

In summary, the solubility of N-(4-iodophenyl)-1-methylsulfanyl-methanimidothioic acid is influenced by its molecular polarity, potential for hydrogen bonding, and interactions with various solvents. It is more soluble in polar solvents, which should be considered when utilizing this compound in various applications.

Interesting facts

Interesting Facts about N-(4-iodophenyl)-1-methylsulfanyl-methanimidothioic acid

N-(4-iodophenyl)-1-methylsulfanyl-methanimidothioic acid is a fascinating compound that is a member of the class of thioamides. Here are some compelling insights into this intriguing molecule:

Thioamide Nature: This compound features a thioamide functional group, which is closely related to amides but contains a sulfur atom instead of an oxygen atom. This substitution imparts unique properties, such as increased nucleophilicity and variations in reactivity.
Role in Medicinal Chemistry: Compounds like this one often serve as valuable intermediates in the synthesis of pharmaceuticals. The modification of the thioamide group can lead to the development of novel drug candidates with potential therapeutic effects.
Iodine Substitution: The presence of iodine in the 4-position of the phenyl ring may enhance the compound's biological activity. Iodinated compounds are frequently studied for their roles in imaging and targeted therapies.
Research Applications: Scientists continually explore thioamide derivatives for their potential applications in various fields, including agrochemicals, where they may exhibit pest control properties.
Structure-Activity Relationship: The structural components in N-(4-iodophenyl)-1-methylsulfanyl-methanimidothioic acid serve as a basis for understanding how modifications can affect biological activity and overall efficacy.

In summary, N-(4-iodophenyl)-1-methylsulfanyl-methanimidothioic acid is not just a compound to be analyzed for its chemical structure; it opens avenues for innovation in medicinal chemistry and beyond. Its unique attributes and potential applications present a rich area for research and exploration.