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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
N-[4-methyl-5-(5-nitro-2-furyl)-1,2,4-triazol-3-yl]acetamide
State
State

At room temperature, Nitrofurazone is in a solid state. It is stable under standard conditions but should be kept away from strong oxidizing agents.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
198.14g/mol
Molar mass
198.1570g/mol
Density
1.6500g/cm3
Appearence

Nitrofurazone is typically a yellow, crystalline solid. It appears as a bright yellow powder.

Comment on solubility

Solubility Profile of N-[4-methyl-5-(5-nitro-2-furyl)-1,2,4-triazol-3-yl]acetamide

N-[4-methyl-5-(5-nitro-2-furyl)-1,2,4-triazol-3-yl]acetamide, with the chemical formula C6H6N4O4, displays intriguing solubility characteristics that are worth exploring. The solubility of this compound is influenced by several factors:

  • Polarity: The presence of the nitro group and the triazole structure contributes to the compound's overall polarity, which can enhance its interaction with polar solvents.
  • Hydrogen bonding: The amide functional group can participate in hydrogen bonding, which may increase solubility in protic solvents, such as water.
  • Solvent choice: Generally, organic solvents like DMSO or DMF may show better solubility compared to non-polar solvents, due to the polar nature of the triazole and nitro groups.

While specific solubility data might not be readily available, it is often observed that compounds with similar structural features tend to show:

  1. Moderate solubility in water, particularly at elevated temperatures.
  2. Good solubility in polar organic solvents.
  3. Poor solubility in non-polar solvents.

In conclusion, understanding the solubility of N-[4-methyl-5-(5-nitro-2-furyl)-1,2,4-triazol-3-yl]acetamide can provide insights into its potential applications in various chemical processes and its behavior in biological systems. As with many compounds, it is crucial to evaluate solubility in the context of its intended use.

Interesting facts

Interesting Facts about N-[4-methyl-5-(5-nitro-2-furyl)-1,2,4-triazol-3-yl]acetamide

N-[4-methyl-5-(5-nitro-2-furyl)-1,2,4-triazol-3-yl]acetamide is a fascinating compound that has drawn attention for its potential applications in various scientific fields. Here are some intriguing points about this compound:

  • Biological Activity: This compound is part of the triazole family, which is known for its diverse biological activities, including antifungal and anti-inflammatory properties. Its unique structure contributes to its effectiveness in these areas.
  • Design and Development: The incorporation of a nitro group within the furan ring is particularly interesting as it influences the reactivity and specificity of the compound, making it a subject of study in medicinal chemistry.
  • Research Implications: Scientists are investigating the potential of this compound as a lead for developing new pharmaceuticals aimed at treating various diseases, including certain types of cancer and infectious diseases.
  • Synthetic Versatility: The synthesis of this compound showcases the versatility of triazoles in organic synthesis, with various methods available to introduce functional groups and modify its activity.
  • Environmental Impact: Its nitro-substituted moiety raises questions about environmental degradation and toxicity, making it important to study how the compound behaves in natural environments.

In summary, N-[4-methyl-5-(5-nitro-2-furyl)-1,2,4-triazol-3-yl]acetamide is more than just a chemical structure; it represents the intersection of innovative synthetic strategies and potential therapeutic applications. As research continues, this compound may open new doors in the realm of chemistry and pharmacology.

Synonyms
10187-80-1
BRN 1018693
ACETAMIDE, N-(4-METHYL-5-(5-NITRO-2-FURYL)-s-TRIAZOL-3-YL)-
s-Triazole, 3-acetamido-4-methyl-5-(5-nitro-2-furyl)-
N-(4-Methyl-5-(5-nitro-2-furyl)-s-triazol-3-yl)acetamide
DTXSID90144306
DTXCID0066797
N-[4-methyl-5-(5-nitrofuran-2-yl)-1,2,4-triazol-3-yl]acetamide
N-[4-Methyl-5-(5-nitro-2-furyl)-4H-1,2,4-triazol-3-yl]acetamide
N-(4-Methyl-5-(5-nitrofuran-2-yl)-4H-1,2,4-triazol-3-yl)acetamide