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N-Acetyl-4-methyl-5-oxo-dithiolo[4,3-b]pyrrole

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Identification
Molecular formula
C8H7NO2S2
CAS number
4036-23-1
IUPAC name
N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide
State
State

At room temperature, this compound is in a solid state. It is not volatile, due to its relatively high melting and boiling points, and remains as a stable crystalline material under standard conditions.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
324.00
Boiling point (Kelvin)
597.15
General information
Molecular weight
213.26g/mol
Molar mass
213.2590g/mol
Density
1.4720g/cm3
Appearence

The compound is typically a crystalline solid. It is generally characterized by its yellow to orange crystals, reflecting the unique sulfur-based structure of the compound which contributes to its distinctive color.

Comment on solubility

Solubility of N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide

N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide is a fascinating compound with unique structural characteristics that influence its solubility. In terms of solubility, the following points are noteworthy:

  • Polar Nature: The presence of functional groups such as amide in its structure typically enhances solubility in polar solvents, especially water.
  • Hydrophobic Regions: The dithiolo moiety may introduce some hydrophobic characteristics that can limit solubility in highly polar solvents.
  • Solvent Compatibility: The compound is likely to be more soluble in organic solvents like dichloromethane or ethyl acetate compared to protic solvents.

Overall, the solubility characteristics of N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide can be summarized as:

  1. If dissolved in polar protic solvents, the solubility is expected to be moderate due to competing hydrophobic interactions.
  2. The optimal solubility conditions may be achieved in moderately polar organic solvents which can balance its dual nature.
  3. Specific experimental data is needed to accurately characterize the solubility profile of this compound under various conditions.

In conclusion, the solubility of N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide is subject to both polar and non-polar interactions, ultimately dictating its behavior in different solvent systems. Further exploration beyond theoretical predictions would provide a clearer understanding of its solubility properties.

Interesting facts

Interesting Facts about N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide

N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide is a unique compound that presents a fascinating area of study within the realms of organic and medicinal chemistry. Here are some interesting facts about this intriguing compound:

  • Complex Structure: The compound features a dithiolo unit, which is a rare structural motif that can contribute to varied chemical properties, potentially enhancing its reactivity and interaction with biological systems.
  • Potential in Medicinal Chemistry: Due to the unique dithiolo and pyrrol structure, this compound could exhibit significant biological activity, making it a candidate for drug development, particularly in the fields of oncology and antimicrobials.
  • Synthesis Potential: The synthesis of N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide may involve innovative pathways that could inspire other scientists to explore similar chemical frameworks, expanding the library of sulfur-containing compounds.
  • Interdisciplinary Interest: This compound could pique the interest of researchers across various fields, from chemists focusing on synthetic routes to pharmacologists examining its biological impact.
  • Environmental Implications: Compounds with sulfur functionalities like dithioles can play a role in environmental chemistry, especially in understanding their interactions with various ecological systems.

As scholars and scientists delve deeper into its properties and applications, N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide may reveal unexpected characteristics that contribute to its potential as a multifunctional compound. The exploration of its effects in diverse chemical and biological systems remains a promising frontier for future research.

Synonyms
Thiolutin
87-11-6
Acetopyrrothin
Acetopyrrothine
NSC 3927
Farcinicine
N-Acetylpyrrothine
BRN 0209485
UNII-02C005Q20B
NSC3927
N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)acetamide
NSC-3927
THIOLUTIN [MI]
N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide
Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-
3-Acetamido-5-methylpyrrolin-4-one(4,3-d)-1,2-dithiole
DTXSID0040624
6-(Acetylamino)-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4H)-one
CHEBI:156450
1,2-DITHIOLO(4.3-b)PYRROL-5(4H)-ONE, 6-ACETAMIDO-4-METHYL-
N-{4-methyl-5-oxo-4H,5H-[1,2]dithiolo[4,3-b]pyrrol-6-yl}acetamide
N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo(4,3-b)pyrrol-6-yl)acetamide
02C005Q20B
6-Acetamido-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4H)-one
N-(4-methyl-5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide
6-Acetamido-4-methyl-1,2-dithiolo[4,3-b]pyrrol-5(4H)-one
1,2-DITHIOLO(4,3-B)PYRROL-5(4H)-ONE, 6-ACETAMIDO-4-METHYL-
6-(ACETAMIDO)-4-METHYL-1,2-DITHIOLO(4,3-B)PYRROL-5(4H)-ONE
Acetamide, N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo(4,3-b)pyrrol-6-yl)-
N-(4-methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide
N-(4-Methyl-5-oxodithiolo(4,3-b)pyrrol-6-yl)acetamide
Farcinicin
Propiopyvothine
N-(4-methyl-5-oxo-4,5-dihydro(1,2)dithiolo(4,3-b)pyrrol-6-yl)acetamide
N-(4-methyl-5-oxo-4H,5H-(1,2)dithiolo(4,3-b)pyrrol-6-yl)acetamide
N-(4-methyl-5-oxo-4H,5H-(1,2)dithiolo(4,3-b)pyrrol-6-yl)ethanimidate
N-{4-methyl-5-oxo-4H,5H-[1,2]dithiolo[4,3-b]pyrrol-6-yl}ethanimidate
1, 6-acetamido-4-methyl-
CHEMBL507026
SCHEMBL1718756
DTXCID8020624
GLXC-10211
BCP17046
HY-N6712
MFCD07370147
AKOS024456672
WLN: T55 BNV FSSJ B1 DMV1
AT02783
NCGC00162456-01
AS-72926
NCI60_003708
Farcinicin; Propiopyvothine; Acetopyrrothine
CS-0029085
G12956
6-Acetamido-4-methyl-1,3-b]pyrrol-5[4H]-one
N-(4,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide
3-Acetamido-5-methylpyrrolin-4-one[4,2-dithiole
Q7784674
6-(Acetylamino)-4-methyl-1,3-b]pyrrol-5[4H]-one
N-(4-methyl-5-oxo-dithiolo[4,3-b]pyrrol-6-yl)acetamide
N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-B]Pyrrol-6-yl)
Acetamide,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-
Acetamide, N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo(4,3-b)pyrrol-6-yl)-(8CI)
Acetamide, N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo(4,3-b)pyrrol-6-yl)-(8CI)(9CI)
Farcinicin;Propiopyvothine;N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)
N-(4-methyl-3-oxo-7,8-dithia-4-azabicyclo[3.3.0]octa-1,5-dien-2-yl)acetamide