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N-(4-nitrophenyl)aziridine-1-carboxamide

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Identification
Molecular formula
C9H9N3O3
CAS number
4808-76-4
IUPAC name
N-(4-nitrophenyl)aziridine-1-carboxamide
State
State

At room temperature, N-(4-nitrophenyl)aziridine-1-carboxamide exists as a solid. The presence of the aziridine ring structure within the molecule influences its physical state, contributing to its crystalline nature.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
207.18g/mol
Molar mass
207.1840g/mol
Density
1.3812g/cm3
Appearence

N-(4-nitrophenyl)aziridine-1-carboxamide is typically a crystalline solid under standard conditions. It presents as a yellow to light brown color, indicative of the nitro group in the compound, which often imparts such hues to aromatic compounds.

Comment on solubility

Solubility of N-(4-nitrophenyl)aziridine-1-carboxamide

N-(4-nitrophenyl)aziridine-1-carboxamide is a chemical compound whose solubility can be influenced by various factors, including its molecular structure and polarity. Understanding its solubility is crucial for applications in pharmaceutical and chemical industries. Here are some key points to consider:

  • Polarity: The presence of both the nitrophenyl and carboxamide groups contributes to the polarity of the compound. Generally, compounds with high polarity exhibit greater solubility in polar solvents such as water.
  • Hydrogen Bonding: The carboxamide functional group may participate in hydrogen bonding with solvents, which can enhance its solubility in water.
  • Solvent Compatibility: N-(4-nitrophenyl)aziridine-1-carboxamide is expected to be more soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol than in non-polar solvents like hexane due to its polar nature.
  • Temperature Effects: Solubility is often temperature-dependent; increasing temperature can lead to higher solubility for many compounds, an important consideration when preparing solutions.

Overall, while specific solubility data may not be readily available for N-(4-nitrophenyl)aziridine-1-carboxamide, its structure suggests a potential for reasonable solubility in appropriate solvents, especially those capable of engaging in hydrogen bonding.

Interesting facts

Interesting Facts about N-(4-nitrophenyl)aziridine-1-carboxamide

N-(4-nitrophenyl)aziridine-1-carboxamide is a fascinating compound owing to its unique structure and potential applications in various fields of chemistry and pharmaceuticals. Here are some noteworthy highlights:

  • Structural Uniqueness: This compound features an aziridine ring, which is a three-membered cyclic amine. The incorporation of the 4-nitrophenyl group adds a powerful electron-withdrawing effect, making the compound highly reactive.
  • Potential Uses: Due to its reactivity, N-(4-nitrophenyl)aziridine-1-carboxamide is of interest in medicinal chemistry as a potential precursor in the synthesis of biologically active molecules.
  • Biological Activity: Compounds containing aziridine structures are often explored for their antiviral and anticancer properties, providing a pathway toward new therapeutic agents.
  • Elasticity Challenge: The strained aziridine ring makes this compound susceptible to ring-opening reactions, a feature that chemists can use to their advantage in synthetic pathways.
  • A Synthetic Curiosity: The methods of synthesizing this compound often involve complex multistep reactions, making it a compelling study subject for students and researchers seeking to understand advanced organic synthesis techniques.

As you delve deeper into the structure and reactivity of N-(4-nitrophenyl)aziridine-1-carboxamide, you’ll uncover the intricate relationships between its unique molecular features and its biological implications. The journey of studying this compound is not only intellectually stimulating but also opens up avenues for groundbreaking discoveries in the world of chemistry.

Synonyms
3647-22-1
BRN 1346959
1-AZIRIDINECARBOXAMIDE, N-(p-NITROPHENYL)-
1-(1-Aziridinyl)-N-(p-nitrophenyl)formamide
Formamide, 1-(1-aziridinyl)-N-(p-nitrophenyl)-
DTXSID00189980
DTXCID60112471