N-(4-oxo-1H-quinazolin-6-yl)acetamide

Identification

Molecular formula

C₁₀H₉N₃O₂

CAS number

3380-34-5

IUPAC name

N-(4-oxo-1H-quinazolin-6-yl)acetamide

State

At room temperature, N-(4-oxo-1H-quinazolin-6-yl)acetamide is in a solid state. Its crystalline form contributes to its stability and solid-state appearance.

Melting point (Celsius)

237.00

Melting point (Kelvin)

510.20

Boiling point (Celsius)

524.30

Boiling point (Kelvin)

797.50

General information

Molecular weight

187.20g/mol

Molar mass

187.1810g/mol

Density

1.3440g/cm³

Appearence

N-(4-oxo-1H-quinazolin-6-yl)acetamide appears as a crystalline solid that is typically off-white or beige in color. These crystalline structures form due to the ordered arrangement of its molecules, as is common with many heterocyclic compounds containing nitrogen and oxygen atoms.

Comment on solubility

Solubility of N-(4-oxo-1H-quinazolin-6-yl)acetamide

N-(4-oxo-1H-quinazolin-6-yl)acetamide, a compound with a notable structure, exhibits interesting solubility characteristics. Understanding its solubility in various solvents is essential for its applications in the pharmaceutical and chemical industries.

Solubility Insights:

Polar Solvents: This compound is likely to be soluble in polar solvents due to the presence of amide functional groups that can form hydrogen bonds.
Nonpolar Solvents: N-(4-oxo-1H-quinazolin-6-yl)acetamide may have limited solubility in nonpolar solvents, as its structure leans towards more polar interactions.
pH Dependence: The solubility can also vary with pH; thus, in acidic or alkaline environments, the solubility profile could change significantly due to ionization effects.
Temperature Influence: Increasing the temperature typically enhances solubility for many organic compounds, and this compound may follow that trend.

In conclusion, while the precise solubility of N-(4-oxo-1H-quinazolin-6-yl)acetamide can vary based on the solvent type and conditions, it is generally expected to show greater solubility in polar environments due to its functional groups. This can be crucial in various chemical processes and applications, making it an intriguing subject for further research.

Interesting facts

Exploring N-(4-oxo-1H-quinazolin-6-yl)acetamide

N-(4-oxo-1H-quinazolin-6-yl)acetamide is a fascinating compound that belongs to the class of quinazolinones, a group renowned for their diverse biological activities. Here are some intriguing facts about this compound:

Biological Significance: Compounds like N-(4-oxo-1H-quinazolin-6-yl)acetamide have shown potential in medicinal chemistry, especially for their roles in drug development. They have been studied for anti-cancer, anti-inflammatory, and anti-microbial properties.
Quinazolinone Backbone: The quinazolinone structure is known to contribute to the pharmacological activity of many drugs. Its ability to interact with various biological targets makes it a valuable scaffold for synthesis and modification.
Synthesis Routes: The synthesis of this compound often involves methods such as cyclization reactions, where precursors form the quinazolinone ring, making it a subject of interest in organic synthesis research.
Research Applications: This compound can serve as a lead structure for the design of new pharmaceuticals, expanding the arsenal of compounds used in treating complex diseases. Its derivatives can be tailored to enhance efficacy and reduce side effects.

As Dr. Jane Goodwin eloquently stated, “The beauty of chemistry lies in the creativity of synthesis and the endless possibilities for discovery.” This sentiment is particularly true with N-(4-oxo-1H-quinazolin-6-yl)acetamide, paving the way for innovative research and potential therapeutic applications.

In summary, the study of this compound is not just a deep dive into its chemical properties but also a journey exploring its potential impacts on science and medicine. With ongoing research, who knows what new frontiers this compound may unveil?