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N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide

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Identification
Molecular formula
C12H12N2O2S
IUPAC name
N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide
State
State

At room temperature, N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide is usually in a solid state. The compound's stability in solid form makes it suitable for storing and handling under regular laboratory conditions.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
248.32g/mol
Molar mass
248.3190g/mol
Density
1.3370g/cm3
Appearence

N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide typically appears as a yellow crystalline solid. Its structure is defined by a thiazin ring, a phenyl group, and an acetamide moiety, which may contribute to variations in color from white to light yellow based on its purity and polymorphic form.

Comment on solubility

Solubility of N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide

N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide exhibits intriguing solubility characteristics that are influenced by its unique molecular structure.

Generally, this compound is:

  • Moderately soluble in polar solvents, such as water and ethanol, due to the presence of polar functional groups.
  • Less soluble in non-polar solvents, such as hexane, which reflects the compound's tendency to favor interactions with polar molecules.

Factors affecting its solubility include:

  1. Hydrogen bonding: The presence of the amide group can engage in hydrogen bonding with solvent molecules, enhancing its solubility.
  2. Molecular size and shape: Larger and more complex molecules may hinder solvation, affecting how well they dissolve in different media.
  3. Temperature: Generally, increased temperatures can improve solubility, as they provide greater energy for molecular interactions.

In the context of pharmaceutical applications, understanding the solubility of this compound is crucial for its bioavailability. As noted, "the solubility profile significantly influences the absorption characteristics of medicinal compounds." Thus, the efficient formulation of this compound requires careful consideration of these solubility factors to optimize its therapeutic efficacy.

Interesting facts

Interesting Facts About N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide

N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide is a fascinating compound that belongs to the class of thiazine derivatives. It has garnered attention in the field of medicinal chemistry due to its potential biological activities. Here are some intriguing aspects of this compound:

  • Biological Activity: Thiazine derivatives, including this compound, are known to exhibit a range of pharmacological properties. They can act as antimicrobial, antitumor, and anti-inflammatory agents, making them valuable candidates for drug development.

  • Synthetic Versatility: The synthesis of thiazine compounds often involves innovative methods, providing organic chemists with opportunities to explore diverse reaction pathways and mechanisms.

  • Structural Importance: The unique structure, featuring a thiazine ring, contributes to the compound's chemical reactivity and interaction with biological targets, often resulting in unique therapeutic effects.

  • Research Potential: As research continues, compounds like N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide are being studied for their role in developing new pharmaceuticals, underscoring the constant evolution of medicinal chemistry.

  • Interdisciplinary Relevance: This compound intersects various fields, including organic chemistry, pharmacology, and material science, showing the broad applicability and importance of thiazine derivatives in various scientific domains.

With ongoing research and studies, the true potential of N-(4-oxo-5-phenyl-5,6-dihydro-1,3-thiazin-2-yl)acetamide continues to unfold, making it a compound of great interest for scientists and researchers alike.

Synonyms
4385-10-8
N-(Tetrahydro-4-oxo-5-phenyl-2H-1,3-thiazin-2-ylidene)acetamide
L 3884
BRN 1124553
2-Acetamido-5-fenildiidro-1,3-tiazin-4-one [Italian]
DTXSID20963128
N-(4-Oxo-5-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl)acetamide
ACETAMIDE, N-(TETRAHYDRO-4-OXO-5-PHENYL-2H-1,3-THIAZIN-2-YLIDENE)-
2-Acetamido-5-fenildiidro-1,3-tiazin-4-one
N-(4-Oxo-5-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl)ethanimidic acid