Skip to main content

N-(4-pyridyl)acetamide

ADVERTISEMENT
Identification
Molecular formula
C7H8N2O
CAS number
104-35-8
IUPAC name
N-(4-pyridyl)acetamide
State
State

At room temperature, N-(4-pyridyl)acetamide is typically found in a solid state. It is stable under normal conditions but should be stored away from strong oxidizing agents to maintain its stability and chemical integrity.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
237.00
Boiling point (Kelvin)
510.15
General information
Molecular weight
136.15g/mol
Molar mass
136.1530g/mol
Density
1.1256g/cm3
Appearence

It is a white crystalline solid that may exhibit slight yellowish tints upon exposure to air or impurities. The crystals are typically well-formed and can be needle-like or prismatic. This compound is used in research and various chemical applications.

Comment on solubility

Solubility of N-(4-pyridyl)acetamide

N-(4-pyridyl)acetamide, with the chemical formula C8H8N2O, exhibits a unique solubility profile that is influenced by its chemical structure. The compound is known to be soluble in a variety of solvents, primarily due to the presence of both the polar acetamide and the pyridine functional groups.

Solubility Characteristics:

  • In Water: N-(4-pyridyl)acetamide demonstrates moderate solubility in water. Its polar nature facilitates hydrogen bonding, which enhances its interaction with water molecules.
  • In Organic Solvents: The compound is more soluble in organic solvents, particularly:
    • Ethanol
    • Acetone
    • Dimethyl sulfoxide (DMSO)
  • Temperature Influence: Increasing the temperature often increases solubility, enabling better dissolution in both water and organic solvents.

To sum up, the solubility of N-(4-pyridyl)acetamide is characterized by its ability to dissolve in both polar and non-polar solvents, allowing for versatile applications in various chemical reactions and processes. This unique solubility makes it a valuable compound in both pharmaceutical and synthetic chemistry contexts.

Interesting facts

Interesting Facts about N-(4-pyridyl)acetamide

N-(4-pyridyl)acetamide is a fascinating compound with significant implications in various fields of chemistry and biology. Here are some intriguing aspects of this compound:

  • Structural Uniqueness: The presence of a pyridine ring in its structure adds unique properties, making it a valuable component in the synthesis of ligands and pharmaceuticals.
  • Biological Activity: Compounds with a pyridine moiety are often known for their diverse biological activities, including antibacterial and antifungal properties. N-(4-pyridyl)acetamide is studied for its potential in medicinal chemistry.
  • Coordination Chemistry: This compound can act as a ligand, binding to metal ions, which is essential in coordination chemistry and catalytic applications.
  • Synthetic Utility: It serves as a versatile intermediate in organic synthesis, allowing for the construction of more complex molecules in pharmaceutical research.
  • Research Potential: Ongoing studies are exploring the potential applications of N-(4-pyridyl)acetamide in drug design and development, highlighting its role in the quest for new therapeutic agents.

In summary, N-(4-pyridyl)acetamide exemplifies the intersection of structure and function in chemical compounds. Its unique properties and applications continue to inspire research and innovation in the field of chemistry.

Synonyms
N-Pyridin-4-ylacetamide
N-4-Pyridinylacetamide
226-018-0
4-Acetamidopyridine
5221-42-1
N-(pyridin-4-yl)acetamide
4-Acetylaminopyridine
Acetamide, N-4-pyridinyl-
Pyridine, 4-acetamido-
Phillips 2038
N-(4-Pyridyl)acetamide
ACETAMIDE, N-(4-PYRIDYL)-
MFCD00720126
BRN 0113907
EINECS 226-018-0
Acetamide, N-4-pyridinyl- (9CI)
4-(Acetylamino)pyridine
SCHEMBL48610
5-22-09-00131 (Beilstein Handbook Reference)
N-(4-Pyridinyl)acetamide #
CHEMBL11959
DTXSID30200258
STK050992
AKOS000281984
AB06982
AS-57198
SY055116
DB-006609
A1883
CS-0313502
NS00032452
D88476
F1018-1441