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N-(4-tert-butoxyphenyl)acetamide

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Identification
Molecular formula
C12H17NO2
CAS number
704-68-3
IUPAC name
N-(4-tert-butoxyphenyl)acetamide
State
State

At room temperature, N-(4-tert-butoxyphenyl)acetamide exists in a solid state.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
344.20
Boiling point (Kelvin)
617.35
General information
Molecular weight
207.27g/mol
Molar mass
207.2740g/mol
Density
1.0824g/cm3
Appearence

The compound N-(4-tert-butoxyphenyl)acetamide typically presents as a white crystalline solid.

Comment on solubility

Solubility of N-(4-tert-butoxyphenyl)acetamide

N-(4-tert-butoxyphenyl)acetamide is a compound that exhibits intriguing solubility characteristics. Understanding its solubility is essential for its applications in various chemical environments.

Factors Affecting Solubility

The solubility of N-(4-tert-butoxyphenyl)acetamide is influenced by several key factors:

  • Polarity: The presence of the tert-butoxy group contributes to its polarity, which can affect solubility in polar versus nonpolar solvents.
  • Hydrogen Bonding: The amide functional group allows for potential hydrogen bonding interactions with solvents, enhancing solubility in protic solvents like water.
  • Temperature: As with many organic compounds, increasing the temperature typically enhances solubility.

Solubility Profiles

In practical terms, the solubility of N-(4-tert-butoxyphenyl)acetamide can often be summarized as follows:

  • Highly soluble in polar organic solvents such as ethanol and methanol.
  • Moderate solubility in water at room temperature, due to the potential for hydrogen bonding.
  • Poor solubility in nonpolar solvents like hexane or toluene.

In conclusion, the solubility of N-(4-tert-butoxyphenyl)acetamide is a nuanced subject, deeply rooted in its structural properties. As we study its behavior in various solvents, we gain insight into its potential applications in different fields of chemistry.

Interesting facts

Interesting Facts About N-(4-tert-butoxyphenyl)acetamide

N-(4-tert-butoxyphenyl)acetamide is a fascinating compound that has garnered attention in both industrial applications and research realms. Here are some intriguing facts:

  • Structure and Functionality: The compound features a unique aromatic structure owing to the tert-butoxy group, which enhances its solubility and interaction with various biological targets.
  • Potential Applications: With its acetamide functional group, N-(4-tert-butoxyphenyl)acetamide is often investigated for its potential use in pharmaceuticals, particularly in designing new drug candidates with enhanced therapeutic profiles.
  • Chemical Properties: The presence of the tert-butoxy group can influence the electronic properties of the compound, which can lead to differences in reactivity and stability compared to similar compounds.
  • Biological Relevance: Some studies have suggested that this compound could exhibit anti-inflammatory or analgesic effects, making it a candidate for further exploration in medicinal chemistry.
  • Research Significance: Ongoing research is addressing how this compound interacts at the molecular level, providing insights that could lead to advances in drug development and therapeutic interventions.

As chemists continue to explore the boundaries of organic chemistry, compounds like N-(4-tert-butoxyphenyl)acetamide remind us of the intricate relationships between structure and function in molecular design. It is truly a compound of interest for both academia and industry!

Synonyms
BUTACETIN
2109-73-1
Tromal
BW 63-90
4'-tert-Butoxyacetanilide
Butacetin [USAN]
Butacetin (USAN)
NSC-106564
2487QE5LU9
BUTACETIN [MI]
BUTACETIN [WHO-DD]
BW-6390
BW 63 90
BW-63-90
UNII-2487QE5LU9
DTXSID60175324
Acetamide, N-(4-(1,1-dimethylethoxy)phenyl)-
Acetamide, N-[4-(1,1-dimethylethoxy)phenyl]-
NSC 106564
DTXCID6097815
N-[4-[(2-methylpropan-2-yl)oxy]phenyl]acetamide
p-tert-Butotyacetanilid
Acetanilide, 4'-tert-butoxy-
N-(4-(tert-Butoxy)phenyl)acetamide
NSC106564
BW 6390
2-Methyl-2-(4-acetaminophenoxy)propane
NSC 106564; Tromal;BW 63-90
N-(4-tert-Butoxyphenyl)acetamide
starbld0001679
SCHEMBL26351
CHEMBL2104218
CHEBI:134873
Acetamide,1-dimethylethoxy)phenyl]-
AKOS027699303
B. W. 63-90
D03181
Acetamide, {N-[4-(1,1-dimethylethoxy)phenyl]}-
SR-01000944395
SR-01000944395-1
Q27253823
Z1260269138