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N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine

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Identification
Molecular formula
C12H14N2OS
CAS number
108012-62-6
IUPAC name
N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine
State
State

At room temperature, N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine is generally found in a solid state. This is consistent with many aromatic amine compounds that have a similar molecular mass and structure.

Melting point (Celsius)
124.00
Melting point (Kelvin)
397.15
Boiling point (Celsius)
395.00
Boiling point (Kelvin)
668.15
General information
Molecular weight
236.32g/mol
Molar mass
236.3200g/mol
Density
1.2700g/cm3
Appearence

N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine typically appears as a crystalline solid. The appearance of this compound can vary slightly depending on the specific synthesis and form, but it is generally a white to off-white product, which is common for many organic compounds with similar structures.

Comment on solubility

Solubility of N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine

The solubility characteristics of N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine can be quite intricate due to its unique structural components. Understanding its solubility can be crucial for applications ranging from pharmaceutical formulations to chemical reactions.

Key Points on Solubility:

  • Polarity: The molecular structure indicates varying degrees of polarity, since it contains both amine and aromatic thiophene groups. The ability to interact with polar and non-polar solvents may influence its solubility.
  • Solvent Interaction: It is likely to be soluble in organic solvents like ethanol or dimethyl sulfoxide (DMSO), while its solubility in water may be limited. The presence of the oxazole ring could further affect solubility due to heteroatom interactions.
  • Temperature Dependency: As with many compounds, solubility may increase with temperature. This is important for applications involving heat, where increased solubility could enhance reactivity or extraction processes.
  • pH Influence: The presence of amino groups may result in solubility changes with different pH, as protonation could alter its solubility in aqueous solutions.

In summary, delving into the solubility of N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine reveals a complex interplay of chemical forces. Understanding these factors is key to maximizing its utility in various chemical contexts.

Interesting facts

Interesting Facts about N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine

N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine represents a fascinating intersection of organic chemistry and pharmacology. Here are some key points that highlight the significance of this compound:

  • Unique Structure: The compound contains a benzothiophene ring, which is known for its role in various bioactive molecules. This structure contributes to the compound's potential biological activity.
  • Versatile Functionality: The inclusion of the oxazol amine group allows for interesting reactivity, making the compound a candidate for development into pharmaceuticals. The ability to modify functional groups can lead to various derivatives with enhanced activities.
  • Potential Applications: Compounds with similar structures have been investigated for their neuroprotective, anti-inflammatory, and anticancer properties. Researchers are intrigued by how this compound might influence pathways in cellular signaling.
  • Synthetic Pathways: The synthesis routes of such compounds often involve complex organic reactions, showcasing the creative aspects of synthetic chemistry. Understanding these pathways is crucial for developing both the compound itself and its analogs.
  • Research Implications: As a focus of ongoing research, this compound invites further exploration into its pharmacokinetic properties and mechanism of action, offering insights into how it may interact with biological systems.

In summary, N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine stands as a prominent example of how the intricate design of chemical structures can lead to significant advancements in medicinal chemistry. As *scientists* delve deeper into its capabilities, it may pave the way for innovative therapeutic agents.

Synonyms
BENZO(c)THIOPHENE, 4,5,6,7-TETRAHYDRO-1-(2-OXAZOLINYL)AMINO-
27632-21-9
1-(2-Amino-2-oxazoline)-3,4,5,6-tetrahydro-2-benzothiophene
DTXSID20182014
RefChem:326322
DTXCID30104505
NSC664321
N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydro-1,3-oxazol-2-amine
CHEMBL1990795
NSC-664321
NCI60_022188
N-(4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-4,5-dihydrooxazol-2-amine
N-(4,5,6,7-Tetrahydro-2-benzothien-1-yl)-4,5-dihydro-1,3-oxazol-2-amine
N-(4,5-Dihydro-1,3-oxazol-2-yl)-N-(4,5,6,7-tetrahydro-2-benzothien-1-yl)amine