Deferoxamine | Solubility of Things

Identification

Molecular formula

C₂₅H₄₈N₆O₈

CAS number

70-51-9

IUPAC name

N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]-N'-(5-aminopentyl)-N'-hydroxy-butanediamide

State

Deferoxamine is solid at room temperature. It is often handled as a dry powder and is typically available as a mesylate salt, which aids in its solubility for medical applications.

Melting point (Celsius)

140.00

Melting point (Kelvin)

413.15

Boiling point (Celsius)

0.00

Boiling point (Kelvin)

0.00

General information

Molecular weight

560.68g/mol

Molar mass

560.6760g/mol

Density

0.7700g/cm³

Appearence

Deferoxamine is typically found as a white to off-white powder. It is hygroscopic and is usually supplied as its mesylate salt form, which may appear slightly different in texture and sheen due to its crystalline nature.

Comment on solubility

Solubility of N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]-N'-(5-aminopentyl)-N'-hydroxy-butanediamide

The solubility of the compound N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]-N'-(5-aminopentyl)-N'-hydroxy-butanediamide (C₂₅H₄₈N₆O₈) is influenced by several factors due to its complex structure and functional groups. Here are some key points to consider:

Structure and Polarity: The presence of multiple amine and hydroxyl groups enhances the compound's polarity, which generally increases its solubility in polar solvents such as water.
Hydrogen Bonding: This compound is likely to form hydrogen bonds with water, which can further contribute to its solubility. Hydrophilic interactions play a significant role in solubilization.
Molecular Size: With 25 carbon atoms and an abundance of functional groups, larger molecules can often exhibit lower solubility compared to smaller molecules, despite their polar features.
Solvent Dependency: It's important to consider the type of solvent. For instance, while the compound may be soluble in aqueous solutions, its solubility may vary in organic solvents.

Overall, while one might expect solubility due to the hydrophilic characteristics, the intricate balance of hydrophobic regions (from the carbon chains) and hydrophilic regions (from amino and hydroxyl groups) makes predicting the exact solubility complex. Any practical application or experimental work would benefit from empirical testing to determine the specific solubility profile in relevant conditions.

Interesting facts

Interesting Facts about N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]-N'-(5-aminopentyl)-N'-hydroxy-butanediamide

N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]-N'-(5-aminopentyl)-N'-hydroxy-butanediamide is a complex chemical compound that presents intriguing features and potential applications. Here are some compelling aspects:

Pharmaceutical Significance: This compound is of particular interest in the field of pharmaceuticals, as modifications in its structure allow for the potential development of novel drug therapies.
Biological Interactivity: The presence of amino groups suggests that it may interact favorably with various biological systems, potentially influencing protein synthesis and cellular signaling pathways.
Versatility in Modifications: The compound contains multiple reactive sites, which offers great versatility in terms of chemical modifications, allowing chemists to tailor its properties for specific applications.
Applications in Drug Delivery: Its structure indicates potential use in targeted drug delivery systems, where it might be designed to release therapeutic agents directly into specific tissues or cells.
Research Opportunities: As a complex organic molecule, it presents numerous opportunities for research in organic synthesis and medicinal chemistry, offering potential insights into new synthetic methodologies.

In summary, N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxo-butanoyl]-hydroxy-amino]pentyl]-N'-(5-aminopentyl)-N'-hydroxy-butanediamide is not just a compound; it's a starting point for exploring a variety of significant scientific avenues that may lead to advancements in health and medicine.

Synonyms

deferoxamine

Desferrioxamine B

70-51-9

DESFERRIOXAMINE

Deferoxamin

Deferrioxamine

Deferoxamine B

Deferrioxamine B

Deferoxaminum

Desferin

DFOM

Desferan

Desferex

Desferral

Desferrin

N-Benzoylferrioxamine B

DF B

Deferoxamina

Deferoxamide B

DFOA

NSC-527604

Ferrioxamine B, N-benzoyl-

Desferriferrioxamin B

Desferoxamine b

N1-(5-Aminopentyl)-N1-hydroxy-N4-(5-(N-hydroxy-4-((5-(N-hydroxyacetamido)pentyl)amino)-4-oxobutanamido)pentyl)succinamide

Dfo-b

HSDB 3311

desferrioxamine-B

UNII-J06Y7MXW4D

Deferoxaminum [INN-Latin]

Deferoxamina [INN-Spanish]

EINECS 200-738-5

J06Y7MXW4D

Ba 33112

BRN 2514118

CHEBI:4356

NSC527604

Butanediamide, N'-(5-((4-((5-(acetylhydroxyamino)pentyl)amino)-1,4-dioxobutyl)hydroxyamino)pentyl)-N-(5-aminopentyl)-N-hydroxy-

N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide

3,9,14,20,25-Pentaazatriacontane-2,10,13,21,24-pentone, 30-amino-3,14,25-trihydroxy-

30-Amino-3,14,25-trihydroxy-3,9,14,20,25-pentaazatriacontane-2,10,13,21,24-pentaone

DTXSID7022887

Ba-33112

EC 200-738-5

1-Amino-6,17-dihydroxy-7,10,18,21-tetraoxo-27-(N-acetyl hydroxylamino)-6,11,17,22-tetraazaheptaeicosane

Deferoxamine (USAN)

N'-(5-((4-((5-(Acetylhydroxamino)pentyl)amino)-1,4-dioxobutyl) hydroxyamino)pentyl)-N-(5-aminopentyl)-N-hydroxybutanediamide

N-(5-(3-((5-Aminopentyl)hydroxycarbamoyl)propionamido)pentyl)-3-((5-(N-hydroxyacetamido)pentyl)carbamoyl)propionohydroxamic acid

Propionohydroxamic acid, N-(5-(3-((5-aminopentyl)hydroxycarbamoyl)propionamido)pentyl)-3-((5-(N-hydroxyacetamido)pentyl)carbamoyl)-

Desferal mesylate

DEFEROXAMINE [USAN]

Deferoxaminum (INN-Latin)

Deferoxamina (INN-Spanish)

N-(5-aminopentyl)-N-hydroxy-N'-[5-(N-hydroxy-3-{[5-(N-hydroxyacetamido)pentyl]carbamoyl}propanamido)pentyl]butanediamide

Deferoxamine B; Deferriferrioxamine B; Deferrioxamine

Deferoximine

Desferioximine

Desferroxamine

MLS002702118

Deferoxamine [USAN:INN]

Butanediamide, N'-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxy-

NSC268993

SMR000058548

Cordaneurin

Desferrioxamin

Perineurin

Desferioxamine B

N'-(5-(acetyl(hydroxy)amino)pentyl)-N-(5-(4-((5-aminopentyl)(hydroxy)amino)-4-oxobutanamido)pentyl)-N-hydroxybutanediamide

N'-{5-[acetyl(hydroxy)amino]pentyl}-N-(5-{4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanamido}pentyl)-N-hydroxybutanediamide

N'-{5-[acetyl(hydroxy)amino]pentyl}-N-[5-({4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanoyl}amino)pentyl]-N-hydroxybutanediamide

N-[5-(3-[(5-Aminopentyl)hydroxycarbamoyl]propionamido)pentyl]-3-([5-(N-hydroxyacetamido)pentyl]carbamoyl)propionohydroxamic acid

N-[5-{3-[(5-Aminopentyl)hydroxycarbamoyl]propionamido}pentyl]-3-{[5-(N-hydroxyacetamido)pentyl]carbamoyl}propionohydroxamic acid

N1-(5-Aminopentyl)-N1-hydroxy-N4-[5-[N-hydroxy-4-[[5-(N-hydroxyacetamido)pentyl]amino]-4-oxobutanamido]pentyl]succinamide

Propionohydroxamic acid, N-[5-[3-[(5-aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]-

deferoxamine-mesylate

DFOB

Desferal (Salt/Mix)

Spectrum_000892

Deferoxamine (Standard)

Prestwick0_000725

Prestwick1_000725

Prestwick2_000725

Prestwick3_000725

Spectrum2_001155

Spectrum3_000376

Spectrum4_000311

Spectrum5_000827

DEFEROXAMINE [MI]

DEFEROXAMINE [INN]

CHEMBL556

DEFEROXAMINE [HSDB]

DEFEROXAMINE [VANDF]

SCHEMBL34571

BSPBio_000650

BSPBio_002131

KBioGR_000922

KBioGR_002429

KBioSS_001372

KBioSS_002435

cid_62881

DEFEROXAMINE [WHO-DD]

DivK1c_000082

Ba 29837 (Salt/Mix)

SPBio_001109

SPBio_002589

BPBio1_000716

CGH-749B

DTXCID002887

ICL-749B

BDBM47715

HY-B1625R

KBio1_000082

KBio2_001372

KBio2_002429

KBio2_003940

KBio2_004997

KBio2_006508

KBio2_007565

KBio3_001351

KBio3_002908

cMAP_000047

NINDS_000082

HMS3604E17

BCP16524

HY-B1625

LMFA08020169

MFCD00242585

WLN: Z5NQV/2VM5NQV/ 21

DEFEROXAMINE, Deferoxamine Mesylate

AKOS016004824

DB00746

FD46531

IDI1_000082

SMP2_000121

NCGC00178802-01

NCGC00178802-02

NCGC00178802-03

DA-72630

MS-30181

NCI60_002181

SMR001550278

SY237696

SBI-0051332.P003

AB00053447

CS-0013559

NS00007870

C06940

D03670

F11488

AB00053447_14

EN300-19748908

Q419618

BRD-K09821361-066-05-0

BRD-K09821361-066-06-8

BRD-K09821361-066-08-4

BRD-K09821361-066-13-4

BRD-K09821361-066-15-9

BRD-K09821361-066-16-7

BRD-K09821361-066-23-3

BRD-K09821361-066-24-1

BRD-K09821361-066-25-8

3,14,20,25-Pentaazatriacontane-2,10,13,21,24-pentone, 30-amino-3,14,25-trihydroxy-

30-Amino-3,25-trihydroxy-3,9,14,20,25-pentaazatriacontane-2,10,13,21,24-pentaone

Butanediamide,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxy-

1-amino-6,17-dihydroxy-7,10,18,21-tetraoxo-27-(n-acetylhydroxylamino)-6,11,17,22-tetraazaheptaeicosane

200-738-5

BUTANEDIAMIDE, N'-(5-((4-((5-(ACETYLHYDROXYAMINO)PENTYL)AMINO)-1,4-DIOXOBUTYL)HYDROXYAMINO) PENTYL)-N-(5-AMINOPENTYL)-N-HYDROXY-

N''''-(5-azanylpentyl)-N-[5-[[4-[5-[ethanoyl(oxidanyl)amino]pentylamino]-4-oxidanylidene-butanoyl]-oxidanyl-amino]pentyl]-N''''-oxidanyl-butanediamide;methanesulfonic acid

N'-

N'-(5-((4-((5-(Acetylhydroxyamino)pentyl)amino)-1,4-dioxobutyl)hydroxyamino)pentyl)-N-(5-aminopentyl)-N-hydroxybutanediamide

N'-[5-(acetyl-hydroxy-amino)pentyl]-N-[5-[3-(5-aminopentyl-hydroxy-carbamoyl)propanoylamino]pentyl]-N-hydroxy-butane diamide

N(4)-(5-(acetyl(hydroxy)amino)pentyl)-N(1)-(5-(4-((5-aminopentyl)(hydroxy)amino)-4-oxobutanamido)pentyl)-N(1)-hydroxybutanediamide

N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-1,4-dioxobutyl]-hydroxyamino]pentyl]-N''''-(5-aminopentyl)-N''''-hydroxybutanediamide;methanesulfonic acid

N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-keto-butanoyl]-hydroxy-amino]pentyl]-N''-(5-aminopentyl)-N''-hydroxy-succinamide;mesylic acid

N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N''''-(5-aminopentyl)-N''''-hydroxybutanediamide;methanesulfonic acid

N~1~-(5-(Acetyl(hydroxy)amino)pentyl)-N~4~-(5-((4-((5-aminopentyl)(hydroxy)amino)-4-oxobutanoyl)amino)pentyl)-N~4~-hydroxysuccinamide

N~4~-{5-[acetyl(hydroxy)amino]pentyl}-N~1~-[5-({4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanoyl}amino)pentyl]-N~1~-hydroxybutanediamide

PROPIONOHYDROXAMIC ACID, N-(5-(3-((5-AMINOPENTYL)HYDROXYCARBAMOYL)PROPIONAMIDO)PENTYL) -3-((5-(N-HYDROXYACETAMIDO)PENTYL)CARBAMOYL-

Propionohydroxamic acid, N-[5-(3-[(5-aminopentyl)hydroxycarbamoyl]propionamido)phentyl]-3-([5-(N-hydroxyacetamido)pentyl]carbamoyl)-

Propionohydroxamic acid, N-[5-[3-[(5-aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[(5-N-hydroxyacetamido)pentyl]carbamoyl]-