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N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide

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Identification
Molecular formula
C14H21ClN2O3S
CAS number
85118-45-4
IUPAC name
N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide
State
State

At room temperature, the compound is a stable solid.

Melting point (Celsius)
203.00
Melting point (Kelvin)
476.15
Boiling point (Celsius)
428.00
Boiling point (Kelvin)
701.15
General information
Molecular weight
344.82g/mol
Molar mass
344.8220g/mol
Density
1.3000g/cm3
Appearence

The compound is typically a white to off-white crystalline powder. It is known for its stability under normal storage conditions.

Comment on solubility

Solubility of N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide

The compound N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide, with the chemical formula C14H21ClN2O3S, presents some intriguing aspects when it comes to its solubility characteristics.

Typically, the solubility of a compound can be influenced by several factors:

  • Polarity: Due to the presence of a sulfonamide group and an amino group, this compound exhibits some polar characteristics that may enhance its solubility in polar solvents like water.
  • Functional Groups: The presence of the 2-chloroacetyl moiety may also affect solubility, potentially interacting favorably with certain solvents due to its electrophilic nature.
  • Hydrogen Bonding: The amino group can participate in hydrogen bonding, which often increases the solubility of organic compounds in polar solvents.
  • Temperature: Solubility may also vary with temperature; typically, higher temperatures can increase solubility, especially in solid compounds.

However, despite these influences, the specific solubility of this compound in various solvents is not extensively documented. Laboratory evaluations would be required to determine exact solubility parameters, which are critical for applications in drug formulation and material science.

In summary, while we can speculate on the solubility of N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide based on its structure and the presence of polar functional groups, empirical data would be essential for precise solubility assessments.

Interesting facts

Interesting Facts about N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide

N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide, often referred to in scientific contexts as a sulfonamide derivative, is a compound with notable pharmaceutical relevance. Here are some engaging facts about this interesting molecule:

  • Pharmaceutical Applications: This compound has potential applications in drug development, particularly as an antibacterial agent due to the sulfonamide functional group, which has a long-standing history in medicinal chemistry.
  • Significance of the Chloroacetyl Group: The presence of the chloroacetyl moiety enhances the reactivity of the compound, enabling various chemical transformations that can lead to the synthesis of more complex analogs.
  • Role in the Body: As a sulfanilamide derivative, it may influence metabolic pathways through its interactions with enzymes. Disruption of these pathways can have therapeutic benefits.
  • Structure-Activity Relationship (SAR): Investigating the SAR of this compound can yield insights into how modifications to its structure can affect antibacterial efficacy, selectivity, and pharmacokinetics.
  • Importance of Amino Substitution: The amino group plays a critical role in its biological activity, making this compound of interest in the design of targeted therapies.

In essence, N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide embodies the complexities of medicinal chemistry and the ongoing quest for novel therapeutic agents. As scholars and researchers delve deeper into its properties, this compound may pave the way for new discoveries in the field of pharmacology.

Synonyms
TOSYLLYSINE CHLOROMETHYL KETONE
Tosyllysyl chloromethane
Chlorotosylamidoaminoheptanone
2104-86-1
Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-
Chloromethane, Tosyllysyl
N-(7-amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzenesulfonamide
Chloromethyl Ketone, Tosyllysine
Ketone, Tosyllysine Chloromethyl
SCHEMBL200245
CHEMBL2316089
DTXSID90859721
PD034268
1-chloro-3-tosylamino-7-amino-2-heptanone
N-(7-Amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzene-1-sulfonamide