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N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide

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Identification
Molecular formula
C14H14N2O6S2
CAS number
83704-61-0
IUPAC name
N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide
State
State

At room temperature, N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide is typically a solid. It retains its stability under standard conditions and should be handled with care to prevent degradation.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
355.00
Boiling point (Kelvin)
628.15
General information
Molecular weight
348.36g/mol
Molar mass
348.3630g/mol
Density
1.3600g/cm3
Appearence

The compound is generally in the form of a crystalline solid. Its color can vary depending on purity and specific isomeric forms, but when pure, it typically forms white or off-white crystals.

Comment on solubility

Solubility of N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide

The solubility of N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide can be influenced by various factors. Here are some key points to consider:

  • Solvent Polarity: This compound may exhibit different solubility profiles in polar versus non-polar solvents. Generally, compounds with sulfonyl groups tend to be more soluble in polar solvents like water due to their ability to form hydrogen bonds.
  • pH Dependence: The solubility can also vary with pH. Compounds that have ionizable groups may become more soluble at certain pH levels, thereby facilitating dissolution.
  • Temperature Sensitivity: Like many chemical compounds, solubility can change with temperature. Increased temperatures often enhance the solubility of solid compounds in liquid solvents.
  • Concentration: The solubility limit in a solvent may be reached, beyond which the compound will precipitate out of solution.

In general, it is important to conduct experimental assays to determine the precise solubility of this specific compound under varying conditions, as theoretical predictions may not capture all nuances of solubility behavior. Understanding these aspects can greatly assist in applications involving N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide, especially in pharmaceutical formulations.

Interesting facts

Interesting Facts about N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide

N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide is a fascinating compound with diverse applications and unique properties that make it of great interest to chemists and researchers alike. Here are some highlights:

  • Pharmaceutical Potential: This compound exhibits notable pharmacological properties, positioning it as a potential candidate for various therapeutic applications, particularly in anti-inflammatory and analgesic treatments.
  • Structural Complexity: Its chemical structure incorporates multiple functional groups, including amino and sulfonyl groups, which contribute to its biological activity and reactivity. The arrangement of these groups can influence how the molecule interacts at a cellular level.
  • Research Interest: Scientists are actively studying N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide in drug design. The compound's ability to modify signaling pathways related to pain and inflammation is particularly intriguing.
  • Cross-disciplinary Relevance: This compound has relevance in fields such as medicinal chemistry, biochemistry, and pharmacology, making it a valuable subject for interdisciplinary research collaborations.
  • Environmental Impact: Understanding the behavior and stability of such compounds in the environment is crucial, as their application in pharmaceuticals could lead to undesired ecological effects, necessitating thorough assessments of their environmental safety.

As with many compounds exhibiting biological activity, studying N-[5-amino-2-(4-aminophenyl)sulfonyl-phenyl]sulfonylacetamide not only enhances our knowledge of chemical interactions but also pushes the boundaries of medicinal chemistry. Future research endeavours could unveil new therapeutic avenues or improve existing treatments.

Synonyms
Acetosulfone
80-80-8
Sulfadiasulfon
SULFADIASULFONE
Acetosulphone
Sulphadiasulphone
N-[5-amino-2-(4-aminophenyl)sulfonylphenyl]sulfonylacetamide
ZT389542XK
Acetosulfon
N-((5-Amino-2-((4-aminophenyl)sulfonyl)phenyl)sulfonyl)acetamide
UNII-ZT389542XK
Benzenesulfonamide, N-acetyl-5-amino-2-((4-aminophenyl)sulfonyl)-
Benzenesulfonamide, N-acetyl-5-amino-2-[(4-aminophenyl)sulfonyl]-
Acetamide,N-[[5-amino-2-[(4-aminophenyl)sulfonyl]phenyl]sulfonyl]-
Sulfadiasulfone [INN]
BD 1 (*sodium salt*)
Promacetin (*sodium salt*)
CI 100 (*sodium salt*)
IA -107 (*sodium salt*)
CHEMBL3306903
SCHEMBL10697113
SULFADIASULFONE [WHO-DD]
DTXSID70859249
CHEBI:135557
N-Acetyl-5-amino-2-((4-aminophenyl)sulfonyl)benzenesulfonamide
N-(6-SULFANILYLMETANILYL)ACETAMIDE
Q27295883
N-Acetyl-5-amino-2-((4-aminophenyl)sulfonyl)-benzenesulfonamide
N-[5-AMINO-2-(4-AMINOPHENYL)SULFONYL-PHENYL]SULFONYLACETAMIDE
ACETAMIDE, N-((5-AMINO-2-((4-AMINOPHENYL)SULFONYL)PHENYL)SULFONYL)-