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N-(5-aminopentyl)-5-chloro-naphthalene-1-sulfonamide

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Identification
Molecular formula
C15H19ClN2O2S
CAS number
Unknown
IUPAC name
N-(5-aminopentyl)-5-chloro-naphthalene-1-sulfonamide
State
State

At room temperature, N-(5-aminopentyl)-5-chloro-naphthalene-1-sulfonamide is in a solid state. The compound's state is common for many sulfonamides which are utilized in various synthetic applications and pharmacological assays.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.00
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.00
General information
Molecular weight
326.85g/mol
Molar mass
326.8500g/mol
Density
1.3000g/cm3
Appearence

N-(5-aminopentyl)-5-chloro-naphthalene-1-sulfonamide typically appears as a white to off-white solid. Due to its specific chemical structure featuring the naphthalene sulfonamide group and the long aminopentyl chain, it might display varying degrees of crystallinity depending on purity and preparation methods.

Comment on solubility

Solubility of N-(5-aminopentyl)-5-chloro-naphthalene-1-sulfonamide

N-(5-aminopentyl)-5-chloro-naphthalene-1-sulfonamide, with the chemical formula C15H19ClN2O2S, exhibits intriguing solubility characteristics that are worth exploring. The solubility of such compounds can be influenced by numerous factors including polarity, pH, and temperature.

Factors Affecting Solubility

  • Polarity: The presence of sulfur and nitrogen functional groups contributes to the compound's polarity, potentially increasing its solubility in polar solvents like water.
  • Hydrogen Bonding: The amino group (–NH2) can engage in hydrogen bonding, enhancing solubility in polar media.
  • Temperature: Elevated temperatures often increase solubility, particularly for solid compounds by providing energy to overcome intermolecular forces.

Prediction of Solubility

Based on its structure, we can summarize the solubility of N-(5-aminopentyl)-5-chloro-naphthalene-1-sulfonamide as follows:

  1. Likely soluble in polar solvents (e.g., water, alcohols).
  2. Potentially low solubility in nonpolar solvents due to the naphthalene structure.

To conclude, the unique features of N-(5-aminopentyl)-5-chloro-naphthalene-1-sulfonamide suggest that it can dissolve in various applications, notably in biological systems where its solubility characteristics may be particularly beneficial. As always, conducting experimental assessments is essential to precisely determine solubility under specific conditions.

Interesting facts

Interesting Facts About N-(5-Aminopentyl)-5-chloro-naphthalene-1-sulfonamide

N-(5-aminopentyl)-5-chloro-naphthalene-1-sulfonamide is a compound that showcases the fascinating interplay between organic chemistry and medicinal applications. This compound belongs to a class of sulfonamides, which have been widely researched due to their biological activity and therapeutic potential. Here are some engaging aspects of this compound:

  • Structural Complexity: This compound contains a naphthalene ring, which contributes to its structural stability and unique chemical properties. The presence of an amine group and a sulfonamide functionality adds to its versatility.
  • Biological Relevance: Sulfonamides have been historically important as antibiotics. They often interfere with bacterial folic acid synthesis, making them valuable in the fight against infectious diseases.
  • Novel Applications: Research into compounds like this one is ongoing, with potential applications in designing new drugs, particularly in areas such as cancer treatment and anti-inflammatory agents.
  • Chlorine Atom Influence: The inclusion of a chlorine atom can significantly affect the chemical reactivity and biological activity of the compound, providing insights into how slight modifications can alter functionality.
  • Amino Group Functionality: The amino group (-NH₂) is often responsible for increased solubility and enhanced interactions with biological targets, which is critical in drug development.

This compound not only demonstrates the relevance of sulfonamide chemistry but also highlights the importance of structural modifications that can lead to enhanced biological properties. As researchers explore its attributes, it continues to inspire the discovery of novel therapeutic agents in medicinal chemistry.

"The beauty of chemistry lies in its ability to transform a simple molecular structure into a complex therapeutic agent responsible for saving lives."

Synonyms
N-(5-aminopentyl)-5-chloronaphthalene-1-sulfonamide
80467-74-9
DTXSID00274426
SCHEMBL9927435
DTXCID70225905