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Dansylcadaverine

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Identification
Molecular formula
C17H25N3O2S
CAS number
10017-52-2
IUPAC name
N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide
State
State

Dansylcadaverine is typically a solid at room temperature. It is stable under normal conditions but should be stored in a cool, dry place to maintain its integrity, particularly to preserve its fluorescent properties.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
409.00
Boiling point (Kelvin)
682.15
General information
Molecular weight
369.47g/mol
Molar mass
369.5150g/mol
Density
1.1900g/cm3
Appearence

Dansylcadaverine is a fluorescent compound characterized by its yellowish crystalline powder appearance. It has a distinctive smell and is known for its bright fluorescence when exposed to ultraviolet light, which makes it particularly useful in biological imaging and fluorescence spectroscopy.

Comment on solubility

Solubility of N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide

N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide, with the molecular formula C17H25N3O2S, exhibits interesting solubility characteristics that are influenced by several factors:

  • Polarity: Due to the presence of the sulfonamide group, this compound demonstrates a degree of polarity, which enhances its solubility in polar solvents such as water.
  • Hydrophobic Interactions: The naphthalene ring contributes to the hydrophobic nature of the molecule, which can affect solubility in non-polar solvents.
  • Amine Groups: The amino groups (-NH2) can form hydrogen bonds with water, further promoting solubility in aqueous solutions.
  • Concentration Dependency: As with many organic compounds, solubility can vary significantly with temperature and concentration; increased temperature may improve solubility.

In summary, it can be expected that N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide will be fairly soluble in polar solvents like water, while its hydrophobic regions may impede solubility in non-polar solvents. Careful consideration of solvent choice, temperature, and concentration is essential for optimizing solubility when working with this compound.

Interesting facts

Exploring N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide

N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide is a fascinating compound that showcases the intricate interplay between chemical structure and biological activity. Here are some intriguing insights about this compound:

  • Structural Complexity: The unique structure of this compound features a naphthalene backbone, which is a fused bicyclic aromatic hydrocarbon, emphasizing the importance of aromatic compounds in organic chemistry.
  • Applications in Research: This compound is often utilized in biochemical research, particularly in studies involving drug design and molecular biology. Its ability to bind specific biological targets makes it an essential tool for scientists in these fields.
  • Biological Activity: Compounds like N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide have shown potential in various therapeutic areas. Their interactions at the molecular level can lead to significant pharmacological effects.
  • Development of Therapeutics: The sulfonamide functional group is prevalent in many antibiotics, indicating a historical significance in the development of antimicrobial agents, enhancing our understanding of microbial resistance.
  • Research Importance: Other compounds containing similar structural motifs are often studied for their ability to modulate biological pathways, offering insights into cell signaling and communication.

In summary, the study of N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide exemplifies the fascinating connections between chemical structure, function, and biological impact in medicinal chemistry. As researchers continue to explore its properties and applications, this compound stands as a testament to the creativity and innovation inherent in the field of chemistry.

Synonyms
Dansylcadaverine
10121-91-2
monodansylcadaverine
n-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide
Monodansyl cadaverine
1-Naphthalenesulfonamide, N-(5-aminopentyl)-5-(dimethylamino)-
UNII-I9N81SC5HD
EINECS 233-326-9
I9N81SC5HD
N-monodansylcadaverine
N-(5-Aminopentyl)-5-dimethylamino-1-naphthalenesulfonamide
CHEBI:52007
N-monodansyl-1,5-diaminopentane
DTXSID40143788
N-(5-Aminopentyl)-5-(dimethylamino)naphthalene-1-sulphonamide
N-(5-Aminopentyl)-5-(dimethylamino)-1-naphthalenesulfonamide; Dansylcadaverine; Monodansylcadaverine;
MFCD00042704
MONODANSYL-CADAVERINE
SCHEMBL107806
CHEMBL5422910
DTXCID7066279
MLEBFEHOJICQQS-UHFFFAOYSA-N
Bio1_000483
Bio1_000972
Bio1_001461
N-(Dimethyl-amino-naphtha-lene-sulfonyl)-1,5-pentane-diamine
Dansylcadaverine, >=97% (TLC)
HY-D1027
KAA12191
AKOS015915995
CS-8078
AS-71334
NS00023037
E77865
Q4154886
Dansylcadaverine, BioReagent, suitable for fluorescence, >=99.0% (HPLC)
233-326-9