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N-(5-aminopentyl)naphthalene-1-sulfonamide

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Identification
Molecular formula
C15H20N2O2S
CAS number
157283-61-1
IUPAC name
N-(5-aminopentyl)naphthalene-1-sulfonamide
State
State

At room temperature, N-(5-aminopentyl)naphthalene-1-sulfonamide is in a solid state. It is stable under normal conditions but should be handled with care, avoiding exposure to atmospheric moisture which could lead to clumping or degradation.

Melting point (Celsius)
136.00
Melting point (Kelvin)
409.15
Boiling point (Celsius)
488.10
Boiling point (Kelvin)
761.25
General information
Molecular weight
302.41g/mol
Molar mass
302.4130g/mol
Density
1.2360g/cm3
Appearence

N-(5-aminopentyl)naphthalene-1-sulfonamide typically appears as an off-white to light brown crystalline solid. The substance is often in a powdered form and is slightly hygroscopic, meaning it may absorb small amounts of moisture from the atmosphere.

Comment on solubility

Solubility of N-(5-aminopentyl)naphthalene-1-sulfonamide

The solubility of N-(5-aminopentyl)naphthalene-1-sulfonamide (C15H20N2O2S) is a topic of considerable interest due to its unique chemical structure. Understanding its solubility profile involves several factors:

  • Polarity: The presence of the naphthalene ring makes it largely hydrophobic, but the sulfonamide group adds a polar character, allowing for some solubility in polar solvents.
  • Temperature Dependance: Like many compounds, solubility can increase with temperature, which may be essential for applications in varying conditions.
  • Solvent Type: It generally exhibits higher solubility in organic solvents such as DMSO or acetone compared to water, indicating a preference for non-polar environments.

As a general rule, compounds with both hydrophobic and hydrophilic components tend to showcase a varied solubility profile. In practical applications, it is often noted that:

  • Solubility in water may be limited, commonly observed in similar sulfonamides due to their complex structure.
  • Higher concentrations of this compound are typically achieved in more polar organic solvents.

In summary, the solubility of N-(5-aminopentyl)naphthalene-1-sulfonamide is multifaceted. While not highly soluble in water, its ability to dissolve in organic solvents offers versatility for various chemical applications. Understanding these solubility characteristics is crucial for optimizing its use in pharmaceutical and industrial contexts.

Interesting facts

Interesting Facts about N-(5-aminopentyl)naphthalene-1-sulfonamide

N-(5-aminopentyl)naphthalene-1-sulfonamide, often referred to as a sulfonamide derivative, is a compound that showcases the fascinating interplay between organic chemistry and medicinal science. Below are some compelling aspects of this compound:

  • Versatile Applications: Sulfonamides are widely recognized for their role in pharmaceutical applications, particularly as antibiotics. N-(5-aminopentyl)naphthalene-1-sulfonamide contributes to this tradition by potentially offering antimicrobial properties.
  • Molecular Structure: The presence of the naphthalene moiety in its structure not only contributes to its unique properties but also enhances its stability and reactivity. Naphthalene derivatives are often studied for their electronic properties and interactions.
  • Amines and Sulfonamides: This compound features both an amine and a sulfonamide functional group, which can lead to diverse reactivity. Such characteristics are crucial in drug design, as they allow for modifications that can fine-tune the biological activity of the compound.
  • Research Potential: The exploration of N-(5-aminopentyl)naphthalene-1-sulfonamide can lead to the development of new drugs with improved efficacy and reduced side effects, making it an exciting topic in medicinal chemistry.
  • Historical Context: The discovery of sulfonamides marked a significant advancement in medicine in the 20th century, paving the way for antibiotic treatments. This compound embodies the ongoing evolution of such discoveries as researchers continue to innovate.

As scientists delve deeper into the world of N-(5-aminopentyl)naphthalene-1-sulfonamide, they aim to unlock the mysteries of its potential applications, reinforcing the idea that the realms of chemistry and medicine are intricately linked.

Synonyms
N-(5-aminopentyl)naphthalene-1-sulfonamide
33956-62-6
SCHEMBL6753337
DTXSID40274425
JADYUKSNNZVACZ-UHFFFAOYSA-N
5-(1-naphthalenesulfonyl)aminopentylamine
PD073543