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N-(5-bromobenzothiophen-3-ylmethyl)-2-chloro-N-ethylethanamine

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Identification
Molecular formula
C13H15BrClNS
CAS number
586965-16-4
IUPAC name
N-[(5-bromobenzothiophen-3-yl)methyl]-2-chloro-N-ethyl-ethanamine
State
State
The compound exists as a solid at room temperature. It can be described as a crystalline powder, often requiring careful storage to maintain its stability.
Melting point (Celsius)
109.00
Melting point (Kelvin)
382.15
Boiling point (Celsius)
328.00
Boiling point (Kelvin)
601.15
General information
Molecular weight
315.69g/mol
Molar mass
315.6850g/mol
Density
1.5540g/cm3
Appearence

The compound is generally encountered as a white to off-white solid when pure. Its coloration may range from colorless to slightly yellow due to minor impurities or exposure to air.

Comment on solubility

Solubility of N-[(5-bromobenzothiophen-3-yl)methyl]-2-chloro-N-ethyl-ethanamine

The solubility of N-[(5-bromobenzothiophen-3-yl)methyl]-2-chloro-N-ethyl-ethanamine is a crucial aspect to consider when evaluating its applications and behavior in various environments. The following points summarize key factors affecting its solubility:

  • Polarity: The presence of the chloro group and the ethyl amine structure may contribute to the polarity of the molecule, potentially enhancing its solubility in polar solvents like water.
  • Aromatic Character: The bromobenzothiophene moiety introduces a significant hydrophobic character, which may hinder aqueous solubility, especially in high concentrations.
  • Solvent Interaction: Understanding the interactions with various solvents—polar vs. non-polar—can provide valuable insights into solubility. It is likely more soluble in organic solvents such as ethanol or DMSO.
  • Temperature Dependence: Solubility may vary with temperature; it is often observed that increasing temperature enhances solubility for many organic compounds.

In summary, while the solubility of N-[(5-bromobenzothiophen-3-yl)methyl]-2-chloro-N-ethyl-ethanamine in water may be limited due to its hydrophobic structure, it could be reasonably soluble in organic solvents. Evaluating this compound's solubility in different environments is essential for applications such as drug formulation and synthesis.

Interesting facts

Interesting Facts About N-[(5-bromobenzothiophen-3-yl)methyl]-2-chloro-N-ethyl-ethanamine

N-[(5-bromobenzothiophen-3-yl)methyl]-2-chloro-N-ethyl-ethanamine is an intriguing compound that belongs to the class of substituted aminobenzenes, known for their diverse applications in organic synthesis and medicinal chemistry. Here are some remarkable points about this compound:

  • Structure and Stability: The presence of both the bromine atom and the chloro group in its molecular structure contributes to its unique reactivity and stability, making it an interesting target for further investigation in chemical reactions.
  • Biological Significance: Compounds with a benzothiophene core are often studied for their various biological activities. They have been associated with antitumor, anti-inflammatory, and antimicrobial properties.
  • Potential Medicinal Applications: Given its structural complexity, this compound may exhibit novel pharmacological effects, potentially leading to the development of new therapeutics for various conditions.
  • Synthetic Routes: The synthesis of this compound exemplifies the use of modern synthetic strategies in organic chemistry, incorporating methods such as coupling reactions and halogenation techniques.

As a compound with a multifaceted chemical profile, N-[(5-bromobenzothiophen-3-yl)methyl]-2-chloro-N-ethyl-ethanamine serves as a fascinating subject in the realms of both academic research and pharmaceutical development. Its unique properties can inspire new avenues for exploration in the synthesis and evaluation of similar compounds.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Exploring compounds like this one can lead to innovative research and surprising discoveries!

Synonyms
Mitotenamine
Mitotenamina
Mitotenaminum
7696-00-6
Mitotenamine [INN:BAN]
UNII-2879S26V4P
MITOTENAMINE [INN]
2879S26V4P
DTXSID10227741
5-Brom-N-(2-chlorethyl)-N-ethylbenzo(b)thiophenmethylamin
5-Bromo-N-(2-chloroethyl)-N-ethylbenzo(b)thiophenemethylamine
5-Bromo-N-(2-chloroethyl)-N-ethylbenzo(b)thiophene-3-methylamine
Benzo(b)thiophenemethylamine, 5-bromo-N-(2-chloroethyl)-N-ethyl-
DTXCID60150232
N-[(5-bromo-1-benzothiophen-3-yl)methyl]-2-chloro-N-ethylethanamine
SCHEMBL2111267
CHEMBL2104935
NS00125486
Q27254274