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N-(5-butyl-1,3,4-thiadiazol-2-yl)-4-chloro-benzenesulfonamide

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Identification
Molecular formula
C12H13ClN4O2S2
CAS number
58650-96-5
IUPAC name
N-(5-butyl-1,3,4-thiadiazol-2-yl)-4-chloro-benzenesulfonamide
State
State

At room temperature, this compound is in a solid state, typically crystalline in structure. Its state, like many sulfonamide compounds, ensures stability and ease of handling in laboratory settings.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
330.50
Boiling point (Kelvin)
603.70
General information
Molecular weight
329.83g/mol
Molar mass
329.8230g/mol
Density
1.4805g/cm3
Appearence

The compound is known to be a solid at room temperature, typically appearing as a crystalline substance. Its specific coloration or transparency is not widely documented, but it is common for sulfonamide derivatives to have a light to off-white color.

Comment on solubility

Solubility of N-(5-butyl-1,3,4-thiadiazol-2-yl)-4-chloro-benzenesulfonamide

The solubility of N-(5-butyl-1,3,4-thiadiazol-2-yl)-4-chloro-benzenesulfonamide in various solvents can provide significant insight into its behavior in both biological and chemical contexts. Evaluating solubility is crucial as it affects the compound's bioavailability and reactivity. Here are some key aspects to consider:

  • Aqueous Solubility: This compound may exhibit limited solubility in water due to its hydrophobic butyl group, which reduces interactions with the solvent.
  • Organic Solvents: It is likely to be more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), or acetonitrile, where its structural traits can enhance solvation.
  • pH Dependence: The presence of the sulfonamide moiety may lead to variations in solubility depending on the pH of the solution, potentially affecting ionization.

As a general rule, solubility can often be predicted by considering the following:

  1. Like dissolves like: Polar solvents generally dissolve polar compounds, while non-polar solvents dissolve non-polar compounds.
  2. Functional groups: The specific functional groups present in the compound significantly dictate its interaction with various solvents.
  3. Temperature effects: Increasing temperature often enhances solubility, although this can vary with specific compounds.

In conclusion, understanding the solubility of N-(5-butyl-1,3,4-thiadiazol-2-yl)-4-chloro-benzenesulfonamide is vital for its application and development in chemical formulations and biological systems.

Interesting facts

Interesting Facts about N-(5-butyl-1,3,4-thiadiazol-2-yl)-4-chloro-benzenesulfonamide

N-(5-butyl-1,3,4-thiadiazol-2-yl)-4-chloro-benzenesulfonamide is a fascinating compound with unique properties and applications, notably in the field of pharmaceuticals and agricultural sciences. Here are some interesting points regarding this compound:

  • Pharmaceutical Potential: With its sulfonamide group, this compound may exhibit antimicrobial properties, making it a candidate for use in antibiotic drugs.
  • Agricultural Applications: The thiadiazole moiety is known for its role in the development of pesticides and herbicides, helping to enhance crop protection and growth.
  • Structural Variability: The presence of both a thiadiazole ring and a sulfonamide group contributes to its versatility, potentially allowing for alterations in its structure to optimize efficacy.
  • Importance of Substituents: The butyl group in this compound can affect its biological activity and solubility, underscoring the significance of side chain variations in drug design.
  • Research Developments: Ongoing studies may explore this compound's interaction with biological systems, which could lead to new insights in medicinal chemistry.

As quoted by many researchers in the field, "The true potential of a chemical compound often lies hidden within its structure, waiting to be unlocked by innovative research." This statement encapsulates the essence of studying compounds like N-(5-butyl-1,3,4-thiadiazol-2-yl)-4-chloro-benzenesulfonamide, emphasizing the importance of chemical exploration and discovery!

In summary, this compound exemplifies the intersection of chemistry, biology, and agriculture, paving the way for advancements that can greatly benefit society.

Synonyms
BUTADIAZAMIDE
Butadiazamid
Butadiazamidum
Butadiazamide [INN]
7007-88-7
butadiazamida
UNII-561DQN958O
561DQN958O
N-(5-Butyl-1,3,4-thiadiazol-2-yl)-p-chlorobenzenesulfonamide
DTXSID20220349
N-(5-Butyl-1,3,4-thiadiazol-2-yl)-4-chlorbenzolsulfonamid
DTXCID70142840
N-(5-butyl-1,3,4-thiadiazol-2-yl)-4-chlorobenzenesulfonamide
SCHEMBL2109869
CHEMBL2106717
NS00125929
Q27261353