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N-(5-Chloro-2,4-dimethoxy-phenyl)-2-fluoro-acetamide

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Identification
Molecular formula
C10H11ClFNO3
CAS number
918044-93-6
IUPAC name
N-(5-chloro-2,4-dimethoxy-phenyl)-2-fluoro-acetamide
State
State

At room temperature, this compound exists in a solid state. This stable state allows for easy transportation and usage in various chemical reactions and research without altering the physical form under normal conditions.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
268.00
Boiling point (Kelvin)
541.15
General information
Molecular weight
243.66g/mol
Molar mass
243.6570g/mol
Density
1.3570g/cm3
Appearence

This compound is typically observed as a white to off-white crystalline solid that may appear slightly fine in texture. Its crystalline nature can affect light transmission, often giving it a reflective characteristic under certain conditions.

Comment on solubility

Solubility of N-(5-chloro-2,4-dimethoxy-phenyl)-2-fluoro-acetamide

The solubility of N-(5-chloro-2,4-dimethoxy-phenyl)-2-fluoro-acetamide can be influenced by several factors, including its chemical structure and the polarity of the solvent used. Some key points to consider include:

  • Polarity: The presence of the dimethoxy groups and the chloro substituent in the aromatic ring can affect polarity.
  • Hydrogen Bonding: The amide functional group can participate in hydrogen bonding, which may enhance solubility in polar solvents.
  • Solvent Compatibility: Commonly, this compound may dissolve well in polar organic solvents such as dimethyl sulfoxide (DMSO) or ethanol, but may have limited solubility in non-polar solvents.

It is often stated that "like dissolves like," which means that for optimal solubility, a similar polarity between the solute and the solvent can be beneficial. Thus, while the solubility of N-(5-chloro-2,4-dimethoxy-phenyl)-2-fluoro-acetamide may be moderate in some solvents, it is crucial for researchers to test various conditions to ascertain exact solubility parameters.

Interesting facts

Interesting Facts about N-(5-chloro-2,4-dimethoxy-phenyl)-2-fluoro-acetamide

N-(5-chloro-2,4-dimethoxy-phenyl)-2-fluoro-acetamide is a fascinating compound that merges elements of organic chemistry with pharmacological potential. Here are some key points to note about this compound:

  • Biological Activity: This compound has garnered attention for its potential therapeutic applications. Its structural features indicate that it might interact with biological targets, making it a candidate for drug development.
  • Structural Complexity: The presence of both fluorine and chlorine atoms contributes to the compound's molecular complexity. Such halogenation can significantly influence the electronic properties, stability, and reactivity of organic molecules.
  • Functional Groups: The acetamide group is known for its role in drug design, often enhancing bioavailability. Meanwhile, the dimethoxyphenyl group can potentially improve lipophilicity, aiding in the compound's ability to cross biological membranes.
  • Research Implications: Ongoing studies might explore the effects of this compound in various biological systems, leading to insights in fields ranging from medicinal chemistry to biochemistry.
  • Chemical Reactions: Due to its functional groups, N-(5-chloro-2,4-dimethoxy-phenyl)-2-fluoro-acetamide may participate in a variety of chemical reactions. For example, it could be subject to nucleophilic substitutions due to the presence of the acetamide functional group.

As a potential building block in the synthesis of other complex molecules, this compound emphasizes the beauty and utility of organic chemistry in creating compounds with therapeutic promise. "The path to discovery is paved with the compounds we create," a sentiment echoing the importance of understanding such chemical structures. Its ongoing exploration in laboratories might reveal even more exciting properties and applications in the future!

Synonyms
23554-60-1
BRN 2124018
ACETANILIDE, 5'-CHLORO-2',4'-DIMETHOXY-2-FLUORO-
5'-Chloro-2-fluoro-2',4'-dimethoxyacetanilide
DTXSID10178143
RefChem:315822
DTXCID40100634
5'-Chloro-2',4'-dimethoxy-2-fluoroacetanilide