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Phenobarbital

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Identification
Molecular formula
C12H12N2O3
CAS number
50-06-6
IUPAC name
N-(5-ethyl-2,6-dioxo-5-phenyl-3-pyridyl)acetamide
State
State

At room temperature, phenobarbital is typically in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
397.70
Boiling point (Kelvin)
670.85
General information
Molecular weight
232.24g/mol
Molar mass
232.2370g/mol
Density
1.2220g/cm3
Appearence

Phenobarbital appears as a white, crystalline powder. It is odorless yet has a slightly bitter taste.

Comment on solubility

Solubility of N-(5-ethyl-2,6-dioxo-5-phenyl-3-pyridyl)acetamide

N-(5-ethyl-2,6-dioxo-5-phenyl-3-pyridyl)acetamide, a complex organic compound, exhibits solubility characteristics that are influenced by its molecular structure and functional groups. Understanding its solubility can be crucial for various applications, such as pharmaceuticals where bioavailability is key.

Key Points on Solubility:

  • Solvent Polarity: The solubility of this compound may vary significantly in different solvents, largely depending on their polarity. Polar solvents (e.g., water, methanol) could enhance its solubility due to potential hydrogen bonding interactions.
  • Hydrophobic Character: The presence of hydrophobic alkyl and aromatic components in the structure may limit solubility in highly polar solvents. Thus, it may be more soluble in non-polar or moderately polar organic solvents such as dichloromethane or ethyl acetate.
  • Temperature Effects: As with many organic compounds, increased temperature generally leads to increased solubility, making it important to consider the thermal conditions during solubility testing.

It is essential to note that the solubility of N-(5-ethyl-2,6-dioxo-5-phenyl-3-pyridyl)acetamide has not been extensively documented, and experimental determination is recommended for precise applications. In conclusion, understanding the solubility of this compound requires a multifaceted approach, taking into account various factors such as solvent type, temperature, and the unique aspects of its chemical structure.

Interesting facts

Interesting Facts about N-(5-ethyl-2,6-dioxo-5-phenyl-3-pyridyl)acetamide

N-(5-ethyl-2,6-dioxo-5-phenyl-3-pyridyl)acetamide is an intriguing compound that finds significance in various fields of research, particularly in medicinal chemistry. Here are some captivating aspects:

  • Pharmacological Potential: This compound is recognized for its potential therapeutic applications, especially as a bioactive molecule. Its structural features may contribute to its efficacy in medicinal formulations.
  • Structural Diversity: The presence of a pyridine ring in its structure allows for a variety of chemical interactions, which can make it a versatile scaffold for drug design. The ethyl and phenyl groups enhance its biological activity and solubility characteristics.
  • Enzyme Inhibition: Studies indicate that compounds resembling N-(5-ethyl-2,6-dioxo-5-phenyl-3-pyridyl)acetamide may exhibit inhibitory activity against certain enzymes, showcasing their potential role in treating various diseases.
  • Synthetic Pathways: Its synthesis involves innovative organic reactions, making it a subject of interest for synthetic chemists. There is ongoing research to optimize these methods to improve yield and efficiency.

In the words of one researcher, "The exploration of compounds like N-(5-ethyl-2,6-dioxo-5-phenyl-3-pyridyl)acetamide represents a frontier in drug discovery that could pave the way for new therapeutic solutions."

This compound is an excellent example of how the intricate design of molecular structures can lead to groundbreaking advancements in health science and pharmaceuticals. Understanding its properties and potential applications continues to inspire scientists around the world.

Synonyms
14387-64-5
ACETAMIDE, N-(1,2,5,6-TETRAHYDRO-2,6-DIOXO-5-ETHYL-5-PHENYL-3-PYRIDINYL)-
N-(5-ethyl-2,6-dioxo-5-phenylpyridin-3-yl)acetamide
BRN 0488921
4-Acetamido-2-ethyl-2-phenylglutaconimide
N-(1,2,5,6-Tetrahydro-5-ethyl-2,6-dioxo-5-phenyl-3-pyridinyl)acetamide
DTXSID70932127
N-(1,2,5,6-Tetrahydro-2,6-dioxo-5-ethyl-5-phenylpyridin-3-yl)acetamide
N-(5-Ethyl-2-hydroxy-6-oxo-5-phenyl-5,6-dihydropyridin-3-yl)ethanimidic acid