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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
N-[(5-nitro-2-furyl)methyleneamino]-2-piperazin-1-yl-acetamide
State
State

At room temperature, nitrofurazone is typically found in a solid state, existing as a crystalline powder. It is stable under normal conditions but should be stored in a cool, dry place to maintain its effectiveness.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.00
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.00
General information
Molecular weight
197.16g/mol
Molar mass
197.1560g/mol
Density
1.6170g/cm3
Appearence

Nitrofurazone typically appears as a bright yellow, crystalline powder. It is commonly used in the treatment of bacterial infections as a topical medication, so it may also be found as an ointment. Its bright yellow color is characteristic, making it easy to identify visually when in powder form.

Comment on solubility

Solubility of N-[(5-nitro-2-furyl)methyleneamino]-2-piperazin-1-yl-acetamide

The solubility of the compound N-[(5-nitro-2-furyl)methyleneamino]-2-piperazin-1-yl-acetamide can be quite intriguing due to its complex structure. Solubility is a key property that influences the behavior of compounds in various applications, particularly in pharmaceuticals.

Here are some important aspects to consider regarding its solubility:

  • Polarity: The presence of polar functional groups, such as the amide and nitro groups, suggests that the compound may exhibit good solubility in polar solvents like water.
  • Hydrogen bonding: The ability to form hydrogen bonds with the solvent can enhance solubility. This compound may engage in such interactions due to the amide portion.
  • Hydrophobic interactions: The furyl group adds a non-polar character, which might lead to reduced solubility in non-polar solvents. Thus, the compound's solubility could vary significantly between different solvents.
  • Temperature dependency: Like many other compounds, its solubility is likely to be influenced by temperature; increased temperature generally leads to improved solubility in most cases.

In practical applications, it is crucial to identify the precise solubility in various solvents to optimize formulations. Understanding these properties can often entail empirical testing, supported by the principles of solute-solvent interactions.

In summary, the solubility of N-[(5-nitro-2-furyl)methyleneamino]-2-piperazin-1-yl-acetamide is influenced by:

  • Polarity of the molecule
  • Capacity for hydrogen bonding
  • Presence of hydrophobic regions
  • Environmental factors such as temperature

These characteristics make solubility a fascinating aspect of this compound, rewarding in its exploration for practical and theoretical chemists alike.

Interesting facts

Interesting Facts about N-[(5-nitro-2-furyl)methyleneamino]-2-piperazin-1-yl-acetamide

N-[(5-nitro-2-furyl)methyleneamino]-2-piperazin-1-yl-acetamide is a fascinating chemical compound that has caught the attention of researchers and chemists alike, mainly due to its unique structure and potential applications. Here are some interesting aspects to consider:

  • Structure Complexity: This compound features a multi-ring system with various functional groups, which contributes to its pharmacological properties. The presence of the nitro group and the piperazine ring makes it particularly intriguing.
  • Pharmacological Interest: Compounds similar to N-[(5-nitro-2-furyl)methyleneamino]-2-piperazin-1-yl-acetamide have been studied for their potential as anti-tumor agents. The 5-nitro-2-furyl moiety is often associated with biological activity, prompting research into its mechanisms of action.
  • Synthetic Pathways: The synthesis of this compound typically involves multiple steps, showcasing the intricate processes involved in modern organic chemistry. Researchers often use various reagents and catalysts to achieve desired yields.
  • Versatile Applications: Beyond anti-cancer properties, there is potential for this compound to be explored in the fields of antimicrobial and antiviral drug development. Its unique structure may enable it to interact with biological targets in novel ways.
  • Research Potential: Ongoing studies aim to investigate the compound's mechanism of action further and its effects on specific cellular pathways. There is a continual quest for understanding how such compounds can contribute to medical advancements.

This compound exemplifies the beauty of chemistry, where the combination of different molecular fragments leads to new possibilities in medicinal chemistry. As researchers delve deeper into its properties and effects, N-[(5-nitro-2-furyl)methyleneamino]-2-piperazin-1-yl-acetamide stands as a testament to the innovative spirit of modern scientific inquiry.