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N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide

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Identification
Molecular formula
C8H5N3O3S2
CAS number
90538-92-0
IUPAC name
N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide
State
State

This compound is a solid at room temperature. It is noted for its stable crystalline form.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
266.27g/mol
Molar mass
266.2820g/mol
Density
1.5600g/cm3
Appearence

N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide appears as a solid. The compound is typically a crystalline powder.

Comment on solubility

Solubility of N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide

N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide, with the chemical formula C9H6N4O2S, presents intriguing characteristics when it comes to solubility.

This compound is known for:

  • Moderate solubility in organic solvents: It tends to dissolve well in polar aprotic solvents such as DMSO and DMF.
  • Limited solubility in water: Being a thiophene derivative, its solubility in aqueous solutions is not significant, which may limit its applications in some biological systems.
  • pH Dependence: The solubility can be affected by pH levels, highlighting the importance of testing under specific conditions to ascertain behavior in biological or environmental settings.

In conclusion, understanding the solubility profile of N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide is crucial for its potential applications. As with many organic compounds, a careful approach must be taken to determine optimal conditions for solubility.

Interesting facts

Interesting Facts about N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide

N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide is a fascinating chemical compound that has garnered significant interest in both pharmaceutical and synthetic chemistry fields. Here are some intriguing aspects of this compound:

  • Biological Activity: This compound exhibits promising biological properties, showing potential as an antibacterial and antifungal agent. Its unique structure allows it to interact with biological targets effectively.
  • Structural Features: The combination of the thiophene and thiazole rings contributes to the compound's stability and reactivity. The presence of a nitro group also plays a crucial role in enhancing its biological properties.
  • Synthetic Pathways: Synthesis of N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide involves several steps, often incorporating techniques such as condensation reactions that are pivotal in creating complex organic molecules.
  • Research Applications: Scholars are continually exploring its derivatives, aiming to optimize its activity and minimize toxicity. This ongoing research can lead to the development of new therapeutic agents.
  • Interdisciplinary Significance: The study of this compound spans multiple disciplines, including medicinal chemistry, material science, and even agricultural applications, showcasing the versatility of organic compounds.

As a scientist or a student, one might appreciate how such a compound exemplifies the intersection of chemistry with real-world applications. Understanding its properties could lead to innovations in drug development, with the potential to address pressing health concerns.

"In the world of chemistry, each compound tells a story, and N-(5-nitrothiazol-2-yl)thiophene-2-carboxamide is no exception."

Synonyms
TENONITROZOLE
3810-35-3
N-(5-nitro-1,3-thiazol-2-yl)thiophene-2-carboxamide
Moniflagon
Tenonitrozol
Atrican
Neo-trichocid
Thenitrazol
Tricosept
Atricam
Tenonitrozole [INN]
Tenonitrozolum
Atrican 109
Tenonitrozol [INN-Spanish]
Tenonitrozolum [INN-Latin]
PBQ7WLE1WP
UNII-PBQ7WLE1WP
2-Thiophenecarboxamide, N-(5-nitro-2-thiazolyl)-
EINECS 223-282-9
TC 109
Atrican (TN)
N-(5-Nitro-2-thiazolyl)-2-thiophenecarboxamide
BRN 0247925
Tenonitrozole (INN)
DTXSID5046277
alpha-Thenoylamino-2-nitro-5-thiazole [French]
TENONITROZOLE [MI]
alpha-Thenoylamino-2-nitro-5-thiazole
TENONITROZOLE [MART.]
TENONITROZOLE [WHO-DD]
DTXCID3026277
Tenonitrozol (INN-Spanish)
Tenonitrozolum (INN-Latin)
TENONITROZOLE (MART.)
tenonitrozolo
P01AX08
223-282-9
4-27-00-04679 (beilstein handbook reference)
N-(5-Nitrothiazol-2-yl)thiophene-2-carboxamide
NCGC00160655-01
CAS-3810-35-3
SR-01000213288
MFCD00866614
2-(alpha-thenoylamino)-5-nitrothiazole
2-(alpha-Thenoylamino)-2-nitro-5-thiazole
MLS001240199
SCHEMBL150446
REGID_for_CID_19646
CHEMBL1082354
Thiophene-2-carboxylic acid (5-nitro-thiazol-2-yl)-amide
CHEBI:135042
ZLOXYEZYWCTXHU-UHFFFAOYSA-N
HMS2233B18
HMS3370N03
EX-A3986
Tox21_111962
STK071581
AKOS003277664
AKOS040754155
Tox21_111962_1
DB13659
NCGC00160655-02
NCGC00160655-03
SMR000674575
NS00030334
6N-021
D07360
G69574
Q7700556
SR-01000213288-1
SR-01000213288-5
BRD-K93862950-001-07-1
N-(5-nitro-1,3-thiazol-2-yl)-2-thiophenecarboxamide