Skip to main content

N-(5-phenyl-2-thienyl)acetamide

ADVERTISEMENT
Identification
Molecular formula
C12H11NOS
CAS number
48016-77-3
IUPAC name
N-(5-phenyl-2-thienyl)acetamide
State
State

At room temperature, N-(5-phenyl-2-thienyl)acetamide is in the solid state. It is stable under normal conditions, handling, and storage. It does not volatilize readily.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
354.00
Boiling point (Kelvin)
627.15
General information
Molecular weight
217.29g/mol
Molar mass
217.2920g/mol
Density
1.2120g/cm3
Appearence

N-(5-phenyl-2-thienyl)acetamide appears as a crystalline solid with a white to off-white color. It is usually fine in texture and may have slight variations in shade depending on purity.

Comment on solubility

Solubility of N-(5-phenyl-2-thienyl)acetamide

N-(5-phenyl-2-thienyl)acetamide, with its unique structure, exhibits interesting solubility characteristics. Understanding its solubility behavior is crucial for various applications in chemistry and pharmaceuticals. Here are some key points to consider:

  • Solvents: N-(5-phenyl-2-thienyl)acetamide is generally soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and acetonitrile. However, it shows limited solubility in water.
  • Influence of Temperature: Increased temperature can enhance its solubility in organic solvents, making it more feasible for various reactions and formulations.
  • pH Sensitivity: The solubility may also be affected by the pH of the solution, indicating that adjusting the pH could be an effective strategy for optimizing its solubility in specific applications.

To summarize, the solubility of N-(5-phenyl-2-thienyl)acetamide is significantly influenced by the choice of solvent and environmental conditions. As stated, "Solubility is the key to unlocking the potential of many chemical substances." Thus, understanding its solubility can lead to better utilization in various chemical processes.

Interesting facts

Interesting Facts about N-(5-phenyl-2-thienyl)acetamide

N-(5-phenyl-2-thienyl)acetamide is a fascinating compound in the realm of organic chemistry, primarily due to its structure and potential applications. This compound showcases a unique interplay between aromatic and heterocyclic systems, which makes it a topic of interest for both researchers and students alike. Here are some intriguing aspects:

  • Structural Composition: The presence of a thienyl ring fused with a phenyl group provides it with intriguing electronic properties. The electron-donating characteristics of aromatic rings can enhance the reactivity of the compound.
  • Pharmaceutical Potential: Compounds similar to N-(5-phenyl-2-thienyl)acetamide have been studied for their biological activities. Research has shown that derivatives of thienyl compounds can exhibit various medicinal properties, including anti-inflammatory and anti-cancer effects.
  • Versatile Synthesis: The production of this compound can be achieved through a variety of synthetic routes, including acylation reactions. This flexibility allows chemists to tailor the compound for specific applications.
  • Intermolecular Interactions: Due to the functional groups present, N-(5-phenyl-2-thienyl)acetamide is likely to engage in hydrogen bonding and π-π stacking interactions, which can influence its properties and behaviors in different environments.

As stated in one research paper, "The reactivity and biological significance of thienyl derivatives cannot be understated, as they open doors for innovative applications in medicinal chemistry." This makes N-(5-phenyl-2-thienyl)acetamide not only a compound of interest in theoretical studies but also an important candidate for further exploration in drug development.

In summary, N-(5-phenyl-2-thienyl)acetamide is more than just a molecular entity; it is a potential bridge between fundamental chemistry and practical pharmacological application. The ongoing study of its properties could lead to exciting discoveries in the future.

Synonyms
N-(5-Phenyl-2-thienyl)acetamide
N-(5-Phenylthiophen-2-yl)acetamide
14770-86-6
BRN 1372059
UNII-B4GHO0T9WY
B4GHO0T9WY
EINECS 238-838-6
ACETAMIDE, N-(5-PHENYL-2-THIENYL)-
DTXSID60163786
DTXCID9086277
238-838-6
N-(5-Phenyl-thiophen-2-yl)-acetamide
MLS000035410
SMR000008985
2-acetylamino-5-phenylthiophene
BAS 00470977
cid_26880
CHEMBL1458077
SCHEMBL13200891
BDBM80351
OSKPBKKQLNRUFG-UHFFFAOYSA-N
HMS2168D05
N-(5-phenyl-2-thiophenyl)acetamide
N-(5-phenylthiophen-2-yl)ethanamide
AKOS024283181
ST062718
NS00024839
AG-690/11961354
SR-01000366560
SR-01000366560-1
Q27274354