Adipic acid bis(2-acetylamide ethyl) ester

Identification

Molecular formula

C₁₀H₂₀N₂O₂

CAS number

622-87-7

IUPAC name

N-(6-acetamidohexyl)acetamide

State

At room temperature, N-(6-acetamidohexyl)acetamide exists as a solid compound. The solid is stable and not volatile under standard conditions of temperature and pressure.

Melting point (Celsius)

124.00

Melting point (Kelvin)

397.00

Boiling point (Celsius)

405.20

Boiling point (Kelvin)

678.40

General information

Molecular weight

200.28g/mol

Molar mass

201.2780g/mol

Density

1.1335g/cm³

Appearence

N-(6-acetamidohexyl)acetamide typically appears as a white crystalline solid. The compound may also be available in powdered form, which is uniform in texture. Its appearance in its pure form is generally free from any impurities or coloration.

Comment on solubility

Solubility of N-(6-acetamidohexyl)acetamide

N-(6-acetamidohexyl)acetamide, with the chemical formula C₁₀H₂₀N₂O₂, exhibits intriguing solubility characteristics due to its structural components.

This compound is expected to be:

Moderately soluble in water: The presence of amide functional groups facilitates hydrogen bonding with water molecules, enhancing its solubility.
Soluble in organic solvents: The hydrocarbon chain allows for good compatibility with non-polar organic solvents, contributing to its potential solubility in various media.

Factors influencing its solubility include:

Temperature: As the temperature increases, solubility generally improves.
pH of the solution: Changes in pH can affect the ionization state of the amide groups, altering solubility.
Presence of other solutes: Certain solutes may enhance or impede solubility through competitive interactions or solvation effects.

Please note that while theoretical predictions can provide insight, actual solubility may require empirical testing in various conditions to determine specific solubility limits.

Interesting facts

Interesting Facts about N-(6-acetamidohexyl)acetamide

N-(6-acetamidohexyl)acetamide, often referred to in scientific literature for its unique properties and applications, is a fascinating compound in the realm of organic chemistry. Here are some intriguing points about this compound:

Chemical Structure: This compound features a unique structure that includes an acetamido group, contributing to its solubility and reactivity. The amide functional group plays a crucial role in biochemical interactions.
Biological Significance: Compounds of this nature are often studied for their potential applications in pharmaceuticals, especially in drug delivery systems due to their ability to interact with biological membranes.
Synthesis: The synthesis of N-(6-acetamidohexyl)acetamide often involves straightforward methods that highlight the versatility of acetamide chemistry. This allows chemists to explore variations of the compound by altering substituents.
Research Applications: Research has shown that amide compounds can serve as useful intermediates in the synthesis of more complex molecules, making them important in the development of new drugs and bioactive compounds. As noted by researchers, "the study of amides is essential for advancing pharmaceutical chemistry."
Potential as a Bioconjugate: The ability to attach to biological agents makes this compound a subject of interest for bioconjugation studies, particularly in targeting specific cells in cancer therapies.

In conclusion, N-(6-acetamidohexyl)acetamide stands out in the field of organic and medicinal chemistry. Its unique structure, potential applications, and the role of amides in biological systems make it an enticing area of study for both seasoned chemists and budding students alike.

Synonyms

3073-59-4

hmba

Hexamethylene bisacetamide

Hexamethylenebisacetamide

N,N'-(Hexane-1,6-diyl)diacetamide

N,N'-Hexamethylenebisacetamide

Hexamethylenediacetamide

N-(6-acetamidohexyl)acetamide

N,N'-DIACETYL-1,6-DIAMINOHEXANE

Acetamide, N,N'-1,6-hexanediylbis-

diacetyldiaminohexane

NSC-95580

N,N'-Diacetylhexamethylenediamine

ACETAMIDE, N,N'-HEXAMETHYLENEBIS-

NSC 95580

CCRIS 7677

N,N'-1,6-Hexanediylbisacetamide

N-[6-(Acetylamino)hexyl]acetamide

NSC95580

BRN 1775764

LA133J59VU

n,n'-hexamethylenebis(acetamide)

N, N'-Diacetylhexamethylenediamine

N,N'-Hexamethylene bis(acetamide)

MFCD00008684

hexamethylene bis(acetamide)

MLS000069460

DTXSID2041044

N,N'-hexane-1,6-diyldiacetamide

4-04-00-01331 (Beilstein Handbook Reference)

Acetamide, N,N'-1, 6-hexanediylbis-

N-{6-[(1-hydroxyethylidene)amino]hexyl}ethanimidic acid

SMR000059046

N,N'-diacetyl-1,6-hexanediamine

hexamethylen bisacetamide

N-(6-(Acetylamino)hexyl)acetamide

Hexamethylene Biscetamide

N-(6-((1-hydroxyethylidene)amino)hexyl)ethanimidic acid

UNII-LA133J59VU

Hexabid

N,N'-hexamethylene-bis-acetamide

Opera_ID_1675

hexamethylene bis-acetamide

NCIMech_000063

SCHEMBL61980

MLS000758275

MLS001074182

MLS001424034

Acetamide,N'-hexamethylenebis-

CHEMBL291481

DTXCID0021044

N,N'-Hexamethylenebis-Acetamide

N,N inverted exclamation marka-Hexamethylene bis(acetamide)

Acetamide,N'-1,6-hexanediylbis-

CHEBI:125472

GLXC-04510

HMS2051E17

HMS2231F06

HMS3371N10

HMS3393E17

N,N'-1,6-Hexanediylbis-Acetamide

CCG-35337

STL282666

AKOS003422084

FH37354

NC00059

SB77455

NCGC00018146-01

NCGC00018146-02

NCGC00018146-03

AS-62044

DA-74110

N,N'-Hexamethylene bis(acetamide), 98%

NCI60_042129

N,N-(HEXANE-1,6-DIYL)DIACETAMIDE

"N,N'-DIACETYL-1,6-DIAMINOHEXANE"

HY-124284

Acetamide, N,N'-1,6-hexanediylbis-(9CI)

CS-0086103

NS00120456

D81997

N-(6-(Acetylamino)hexyl)acetamide (ACD/Name 4.0)

Q3732771

BRD-K04710043-001-17-8

5D4