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N-(6-fluoro-9H-fluoren-2-yl)acetamide

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Identification
Molecular formula
C15H12FNO
CAS number
100700-11-4
IUPAC name
N-(6-fluoro-9H-fluoren-2-yl)acetamide
State
State

This compound is in a solid state at room temperature, characterized by its crystalline structure.

Melting point (Celsius)
197.00
Melting point (Kelvin)
470.15
Boiling point (Celsius)
463.00
Boiling point (Kelvin)
736.15
General information
Molecular weight
241.26g/mol
Molar mass
241.2620g/mol
Density
1.3342g/cm3
Appearence

N-(6-fluoro-9H-fluoren-2-yl)acetamide is typically found as an off-white to pale yellow crystalline solid. It is known for its structural fluorescence derived from the fluorenyl moiety.

Comment on solubility

Solubility of N-(6-fluoro-9H-fluoren-2-yl)acetamide

N-(6-fluoro-9H-fluoren-2-yl)acetamide, with its complex structure, exhibits intriguing solubility characteristics. Here are some key points to consider:

  • Solvent Interaction: This compound is likely to be more soluble in organic solvents such as ethanol and dichloromethane due to its hydrophobic fluorenyl moiety.
  • Water Solubility: It may have limited solubility in water. The presence of the acetamide group can enhance interaction with aqueous environments to some extent, but steric factors from the fluorenyl group could impede solubility.
  • Temperature Effects: Like many organic compounds, solubility can increase with temperature, affecting its behavior in solution under varying conditions.
  • Molecular Interactions: Hydrogen bonding potential due to the acetamide functional group may also play a role in the solubility profile, especially in polar solvents.

In summary, while N-(6-fluoro-9H-fluoren-2-yl)acetamide may display solubility in certain organic solvents, its overall solubility profile is complex and dependent on the interplay of various molecular interactions and solvent properties.

Interesting facts

Interesting Facts about N-(6-fluoro-9H-fluoren-2-yl)acetamide

N-(6-fluoro-9H-fluoren-2-yl)acetamide is a fascinating compound that showcases the interplay between aromatic chemistry and synthetic applications. Here are some interesting insights:

  • Fluorine's Influence: The presence of fluorine in this compound contributes notable electronic and steric properties. Fluorine's electronegativity can enhance reactivity, making compounds like this particularly interesting for medicinal chemistry.
  • Aromatic Structure: This compound is based on the fluorenyl unit, characterized by its unique fused ring system. Aromatic compounds like fluorenes are known for their stability and can engage in various chemical reactions, making them essential in material science and organic synthesis.
  • Applications in Pharmaceutical Chemistry: Compounds similar to N-(6-fluoro-9H-fluoren-2-yl)acetamide are often explored for their potential as pharmaceuticals. Their structural features may contribute to biological activity, which scientists aim to leverage in drug design.
  • Synthetic Versatility: The ability to modify the fluorenyl group allows chemists to create derivatives with tailored properties. This versatility opens pathways to develop new materials, dyes, and biologically active compounds.
  • Research Significance: In research, studying compounds like N-(6-fluoro-9H-fluoren-2-yl)acetamide can provide insights into reaction mechanisms and the design of new compounds with enhanced properties.

Overall, N-(6-fluoro-9H-fluoren-2-yl)acetamide is more than just a chemical formula; it represents a bridge between theoretical research and practical applications in various scientific fields.

Synonyms
6-Fluoro-2-faa
2823-94-1
6-Fluoro-2-acetylaminofluorene
ACETAMIDE, N-(6-FLUOROFLUOREN-2-YL)-
N-(6-Fluorofluoren-2-yl)acetamide
Acetamide, N-(6-fluoro-9H-fluoren-2-yl)-
acetamide,n-(6-fluorofluoren-2-yl)-
NSC 74971
BRN 2737872
NSC74971
NCIOpen2_003861
CHEMBL84495
DTXSID90182485
NSC-74971
WLN: L B656 HHJ DF KMV1
Acetamide,n-(6-fluoro-9h-fluoren-2-yl)-
DS-006292