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Psilocybin

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Identification
Molecular formula
C12H17N3O4P
CAS number
520-52-5
IUPAC name
N-[(6aR,9R,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl]-3,5-dimethyl-pyrazole-1-carboxamide
State
State

At room temperature, psilocybin is a solid, typically found as a crystalline powder.

Melting point (Celsius)
138.00
Melting point (Kelvin)
411.15
Boiling point (Celsius)
278.40
Boiling point (Kelvin)
551.55
General information
Molecular weight
204.25g/mol
Molar mass
204.2510g/mol
Density
1.7800g/cm3
Appearence

Psilocybin is a crystalline solid, typically occurring in a white to off-white color. In its pure form, it appears as a powder which is odorless, with fine crystals or can appear as a crystalline solid.

Comment on solubility

Solubility of N-[(6aR,9R,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl]-3,5-dimethyl-pyrazole-1-carboxamide

The solubility of N-[(6aR,9R,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl]-3,5-dimethyl-pyrazole-1-carboxamide can be affected by various factors. Understanding these factors is crucial for applications in pharmaceuticals and other fields. Here are a few points to consider:

  • Polarity: The compound features multiple functional groups which impact its polarity. The presence of the carboxamide group typically increases water solubility.
  • Hydrogen bonding: The potential for intramolecular and intermolecular hydrogen bonding can further influence solubility, particularly in polar solvents.
  • Solvent choice: Different solvents may offer varying degrees of solubility. For instance, organic solvents like DMSO or alcohol might dissolve the compound better than water.
  • Temperature: Generally, increasing temperature can enhance solubility for many compounds, but this is not universally true. Specific tests should verify this for N-[(6aR,9R,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl]-3,5-dimethyl-pyrazole-1-carboxamide.

In conclusion, while the exact solubility profile of this compound may require empirical investigation, its complex structure suggests that both polarity and functional groups significantly contribute to its solubility characteristics. Understanding these aspects can facilitate its application in relevant fields.

Interesting facts

Interesting Facts about N-[(6aR,9R,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl]-3,5-dimethyl-pyrazole-1-carboxamide

This compound, known for its intricate structure, showcases the interplay between indole and pyrazole, two significant frameworks in medicinal chemistry. Its unique design allows for a variety of biological activities, making it a subject of interest in drug discovery.

Key Features:

  • Complex Structure: The structure features a fused polycyclic system which contributes to its potential biological activities.
  • Biological Significance: Compounds with similar frameworks have been studied for their neuroprotective and anti-inflammatory properties.
  • Versatile Derivatives: The presence of multiple functional groups provides avenues for modification, potentially enhancing its pharmacological profile.
  • Synthesis Challenges: The synthesis of such complex molecules often requires advanced techniques and careful reaction management to ensure yield and purity.

As researchers delve deeper into compounds like this, they aim to unlock new therapeutic avenues. In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This compound exemplifies how intricate designs can lead to innovative solutions in drug design.

Furthermore, studies exploring the interactions of this compound with biological targets can reveal insights into its mechanism of action, paving the way for future advancements in therapeutic interventions.

Synonyms
METOQUIZINE
7125-67-9
Metoquizina
2DW6SEL94L
N-[(6aR,9R,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinolin-9-yl]-3,5-dimethylpyrazole-1-carboxamide
Metoquizinum
1H-Pyrazole-1-carboxamide, 3,5-dimethyl-N-(4,6,6a,7,8,9,10,10a-octahydro-4,7-dimethylindolo(4,3-fg)quinolin-9-yl)
N-((6aR,9R,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)-3,5-dimethyl-1H-pyrazole-1-carboxamide
Ly 42406
Lilly 42406
Metoquizine [USAN:INN]
UNII-2DW6SEL94L
3,5-Dimethyl-N-(4,6,6a,7,8,9,10,10a-octahydro-4,7-dimethylindolo(4,3-fg)quinolin-9-yl)pyrazole-1-carboxamide
3,5-Dimethyl-N-(4,6,6a,7,8,9,10,10a-octahydro-4,7-dimethylindolo[4,3-fg]quinolin-9-yl)pyrazole-1-carboxamide
METOQUIZINE [INN]
Metoquizine (USAN/INN)
METOQUIZINE [USAN]
SCHEMBL667598
CHEMBL3989641
DTXSID90221424
N-(1,6-Dimethyl-8beta-ergolinyl)-3,5-dimethyl-1-pyrazolcarboxamid
AKOS040747159
3,5-Dimethyl-N-(4,6,6a,7,8,9,10,10a-octahydro-4,7-dimethyl-indolol(4,3-f,g)chinolin-9-yl)pyrazol-1-carboxamid
3,5-Dimethyl-N-(4,6,6a,7,8,9,10,10a-octahydro-4,7-dimethylindolo(4,3-fg)-9-yl)pyrazole-1-carboxamide
NS00126293
D05012
Q27254602