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7-Amino-3-(hydroxyimino)indolin-2-one

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Identification
Molecular formula
C10H11N3O
CAS number
92591-12-5
IUPAC name
N'-(7-amino-1H-indol-3-yl)-N-hydroxy-acetamidine
State
State

At room temperature, the compound is typically in a solid state. It is stable under normal conditions but should be handled with care to avoid moisture as it may be hygroscopic.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
352.00
Boiling point (Kelvin)
625.15
General information
Molecular weight
204.21g/mol
Molar mass
204.2060g/mol
Density
1.5032g/cm3
Appearence

The compound appears as a white to off-white crystalline solid. It may have a slight odor specific to hydrazine derivatives.

Comment on solubility

Solubility of N'-(7-amino-1H-indol-3-yl)-N-hydroxy-acetamidine

The solubility of N'-(7-amino-1H-indol-3-yl)-N-hydroxy-acetamidine is influenced by several factors, including its functional groups and overall molecular structure. This compound features both amine and hydroxyl groups, which can significantly impact its behavior in various solvents.

Key Points on Solubility:

  • Water Solubility: The presence of the hydroxyl group typically enhances water solubility due to the ability to form hydrogen bonds with water molecules.
  • Organic Solvents: The indole portion of the molecule may impart limited solubility in non-polar organic solvents. This indicates a potential preferential solubility in moderately polar solvents.
  • pH Dependence: The solubility may vary with pH, as the protonation state of the amine can influence the compound's interaction with water.

In general, it is often observed that compounds with similar structural motifs show diverse solubility behaviors. Thus, while N'-(7-amino-1H-indol-3-yl)-N-hydroxy-acetamidine is expected to have a reasonable solubility in aqueous environments due to its functional groups, its specific solubility can only be confirmed through experimental testing.

Interesting facts

Interesting Facts about N'-(7-amino-1H-indol-3-yl)-N-hydroxy-acetamidine

N'-(7-amino-1H-indol-3-yl)-N-hydroxy-acetamidine, often referred to in the field of medicinal chemistry, showcases a remarkable combination of structural features that contribute to its diverse biological activities. This compound is particularly noteworthy for its role in drug discovery and development due to the following characteristics:

  • Biological Activity: This compound has demonstrated potential as a pharmacological agent, acting on numerous biological targets. Its indole structure plays a crucial role in mediating interactions with various receptors.
  • Research Importance: Compounds with indole scaffolds are widely studied due to their occurrence in natural products and their effectiveness in pharmaceuticals. They are known to possess anti-cancer, anti-inflammatory, and analgesic properties.
  • Synthetic Utility: The presence of a hydroxy group enhances its reactivity, often making it a valuable intermediate in synthetic organic chemistry. This reactivity allows for further transformations into more complex molecules.
  • Mechanistic Studies: Scientists are intrigued by the mechanism through which this compound interacts within biological systems, paving the way for innovations in targeting specific pathways involved in diseases.

As the study of small molecules continues to evolve, N'-(7-amino-1H-indol-3-yl)-N-hydroxy-acetamidine remains a subject of extensive research. The compound exemplifies the excitement of chemistry in understanding the intricate connections between molecular structure and biological function. As a scientist or student engaging with this compound, one might think, "Each molecule tells a story; let’s uncover its plot."

Synonyms
N'-(7-amino-1H-indol-3-yl)-N-hydroxyethanimidamide
7632-15-7
DTXSID60274765