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Lysergic acid diethylamide

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Identification
Molecular formula
C20H25N3O
CAS number
50-37-3
IUPAC name
N-(7-benzyl-2-hydroxy-4-isopropyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
State
State

Solid: Typically a crystalline solid at room temperature. It is known for its stability in this form and is usually stored under controlled conditions to maintain its efficacy.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
291.37g/mol
Molar mass
291.3670g/mol
Density
1.5500g/cm3
Appearence

The compound typically presents as a white or off-white crystalline powder. In some forms, it can also be seen as small crystal structures or in a crystalline salt form. It is highly potent and small quantities are usually sufficient for its intended uses.

Comment on solubility

Solubility of N-(7-benzyl-2-hydroxy-4-isopropyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide (C20H25N3O)

The solubility of N-(7-benzyl-2-hydroxy-4-isopropyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide can be influenced by various factors:

  • Polarity: The presence of polar functional groups, such as hydroxyl and amide groups, can enhance solubility in polar solvents.
  • Hydrogen bonding: The ability of the compound to form hydrogen bonds may increase its solubility in solvents capable of engaging in hydrogen bonding.
  • Molecular weight: Higher molecular weight generally correlates with lower solubility in many cases, particularly in organic solvents.
  • Solvent choice: Solubility can vary significantly between different solvents (e.g., water, ethanol, methanol), and it is crucial to choose the right one depending on the target application.

Generally speaking, the solubility of this compound in common solvents may vary, making it imperative to conduct solubility tests. **It is vital** to provide accurate solubility data, as it can greatly affect the performance and application of the compound in pharmaceutical formulations or chemical processes. Understanding solubility characteristics can help in optimizing its usage in various contexts.

Interesting facts

Exploring N-(7-benzyl-2-hydroxy-4-isopropyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

This compound is a fascinating example of a complex organic molecule that falls under the category of indole derivatives. It showcases a remarkable structural diversity due to the presence of various functional groups and the intricate ring systems, which significantly influence its chemical properties and potential applications.

Key Features:

  • Structural Complexity: The compound consists of multiple fused rings and functional groups, providing a rich playground for studying various chemical interactions.
  • Biological Relevance: Many indoles and similar representatives are known for their pharmacological properties. This compound could possibly exhibit various biological activities, making it a target for drug development.
  • Potential Applications: Due to its unique chemical structure, it is important in medicinal chemistry, particularly in the development of new therapeutics.
  • Diverse Functionalization: The presence of hydroxyl, dioxo, and carbamide groups offers various sites for further chemical modification, enhancing its potential utility in synthesis.

As chemists dive deeper into the analysis of such compounds, they often ponder the intricacies of their reactivity and potential implications in broader chemical contexts. It is worth noting that structural variations can lead to substantial differences in biological activity, and studying these could yield valuable insights.

In the words of a seasoned chemist, "The beauty of organic chemistry lies not just in the compounds themselves but in the possibilities they hold." Each novel compound like this one tells a story of molecular architecture and its potential impact on scientific advancements.

Synonyms
Ergocristine, dihydro-
NSC409663
N-(7-Benzyl-2-hydroxy-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
GTPL278
CHEMBL1967279
BDBM32638
CHEBI:91714
N-[7-benzyl-2-hydroxy-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene-4-carboxamide
NSC-409663
NCGC00181119-01
NCI60_003928
L000676
BRD-A44701612-066-01-9