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N-Hydroxypurine

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Identification
Molecular formula
C5H5N5O
CAS number
299-23-8
IUPAC name
N-(7H-purin-6-yl)hydroxylamine
State
State
N-Hydroxypurine is typically a solid at room temperature. It remains stable under standard conditions and does not undergo decomposition easily, making it a compound that is handled with standard laboratory safety precautions.
Melting point (Celsius)
188.00
Melting point (Kelvin)
461.15
Boiling point (Celsius)
785.00
Boiling point (Kelvin)
1 058.15
General information
Molecular weight
137.11g/mol
Molar mass
137.1100g/mol
Density
0.0000g/cm3
Appearence

N-Hydroxypurine typically appears as a white crystalline powder. The crystals can be very fine and powdery, characteristic of many organic compounds when purified.

Comment on solubility

Solubility of N-(7H-purin-6-yl)hydroxylamine

N-(7H-purin-6-yl)hydroxylamine, a compound derived from purine, exhibits unique solubility characteristics that merit attention. Understanding its solubility profile is crucial for applications in pharmaceuticals and biochemistry.

Solubility Characteristics:

  • Solvent Dependence: This compound is generally soluble in polar solvents such as water and alcohols, making it suitable for various chemical reactions and formulations.
  • pH Sensitivity: The solubility can be affected by the pH of the solution; optimal solubility occurs in mildly acidic to neutral conditions.
  • Temperature Effects: Like many organic compounds, increased temperature often leads to enhanced solubility, allowing for better dissolution in solvents at elevated temperatures.
  • Complexation: The ability of N-(7H-purin-6-yl)hydroxylamine to form complexes with metal ions may influence its solubility and bioavailability in different environments.

In summary, the solubility of N-(7H-purin-6-yl)hydroxylamine is highly dependent on several factors including solvent choice, pH levels, and temperature. Understanding these variables is essential for maximizing its effectiveness in practical applications.

Interesting facts

Interesting Facts about N-(7H-purin-6-yl)hydroxylamine

N-(7H-purin-6-yl)hydroxylamine is a fascinating compound that lends itself to a variety of intriguing applications and properties. As a derivative of purine, its structure is integral to many biological processes, especially in the realm of molecular biology and biochemistry.

Biological Importance

  • Role in Nucleic Acids: This compound relates closely to purines, which are crucial components of nucleic acids like DNA and RNA, playing a significant role in genetic information storage and transfer.
  • Potential in Drug Discovery: It has been studied for its potential applications in pharmaceuticals, particularly as certain hydroxylamine derivatives exhibit properties that can inhibit specific enzymes.
  • Antioxidant Properties: Some studies suggest that compounds like N-(7H-purin-6-yl)hydroxylamine may possess antioxidant properties, which could help mitigate oxidative stress in biological systems.

Chemical Characteristics

This compound showcases a unique blend of chemical properties, including:

  • Hydroxylamine Group: The presence of the hydroxylamine functional group (–NH2OH) is notable for its reactivity, making it a useful agent in organic synthesis and modification reactions.
  • Stability Issues: Hydroxylamines are known for their instability under certain conditions, which may lead to side reactions, making handling and storage an interesting challenge for chemists.

Research and Applications

Research into N-(7H-purin-6-yl)hydroxylamine spans multiple disciplines:

  • Genetic Research: Its application extends to studies involving nucleotide synthesis and modification.
  • Cancer Research: Investigating its potential to act as an anti-cancer agent offers avenues for developing novel treatment strategies.

In summary, N-(7H-purin-6-yl)hydroxylamine represents more than just a chemical entity; it embodies the intricate relationship between structure and function in biochemical pathways, making it an essential subject of study within the fields of chemistry and biology.

Synonyms
6-N-Hydroxylaminopurine
5667-20-9
N-(7H-purin-6-yl)hydroxylamine
6-Hydroxyaminopurine
N-Hydroxyadenine
6-Hydroxylaminopurine
N(6)-Hydroxyadenine
N-Hydroxy-1H-purin-6-amine
N-Hydroxy-1H-adenine
ADENINE, N-HYDROXY-
1H-Purin-6-amine, N-hydroxy-
CCRIS 2558
EINECS 227-125-5
NSC 516286
CHEBI:78235
6-N-hydroxyaminopurine
AI3-60188
N(6)-hydroxyaminopurine
N(6)-hydroxylaminopurine
1H-Purin-6-amine, N-hydroxy-(9CI)
227-125-5
6-HAP
HAP
HAP (VAN)
N6-hydroxyadenine
6H-Purin-6-one, 1,7-dihydro-, oxime
N-(7H-Purin-6-yl);hydroxylamine
purine, 6-hydroxylamino-
6-(N-Hydroxyl)aminopurine
N-Hydroxy-9H-purin-6-amine
SCHEMBL160073
CHEMBL393474
DTXSID4044959
SCHEMBL17176886
CBCQWVQNMGNYEO-UHFFFAOYSA-N
GLXC-21198
N-(9H-purin-6-yl)-hydroxylamine
NSC516286
WLN: T56 BM DN FN HNJ IMQ
AKOS015904882
AKOS025148691
AKOS028109002
HY-W131303
NSC-516286
BS-52906
NCI60_004253
PD214668
CS-0197293
N-(3,9-dihydropurin-6-ylidene)hydroxylamine
NS00033562
A10878
Q27147693