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Clorazepate Dipotassium

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Identification
Molecular formula
C16H11ClN2O3
CAS number
57109-90-7
IUPAC name
N-[(8-chlorobenzo[b][1,4]benzothiazepin-6-yl)methyl]-N',N'-dimethyl-ethane-1,2-diamine
State
State

At room temperature, Clorazepate Dipotassium is found in a solid state, typically as a powder. This physical property facilitates its handling and use in various pharmaceutical applications, including tablets and capsules.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
458.00
Boiling point (Kelvin)
731.15
General information
Molecular weight
348.89g/mol
Molar mass
348.8900g/mol
Density
0.9000g/cm3
Appearence

Clorazepate dipotassium generally appears as white or off-white crystalline powder. It is slightly soluble in water but soluble in alcohol, making it easy to handle in pharmaceutical formulations.

Comment on solubility

Solubility of N-[(8-chlorobenzo...1,4]benzothiazepin-6-yl)methyl]-N',N'-dimethyl-ethane-1,2-diamine

The solubility of N-[(8-chlorobenzob[1,4]benzothiazepin-6-yl)methyl]-N',N'-dimethyl-ethane-1,2-diamine is influenced by several factors due to its complex structure. Here are some key points regarding its solubility:

  • Polarity: The presence of functional groups in the molecule affects its overall polarity. Generally, compounds with polar functional groups are more soluble in polar solvents.
  • Hydrogen Bonding: The potential to form hydrogen bonds with solvents can significantly enhance solubility. This compound may participate in hydrogen bonding due to its amine functional groups, making it more soluble in alcohols and water under certain conditions.
  • Solvent Choice: Solubility is highly dependent on the solvent used. While it may show good solubility in protic solvents (such as water and alcohol), its solubility could vary in non-polar organic solvents.
  • Temperature: Like many chemical compounds, solubility can increase with temperature. Thus, heating the solution may improve the dissolution of N-[(8-chlorobenzob[1,4]benzothiazepin-6-yl)methyl]-N',N'-dimethyl-ethane-1,2-diamine.

In summary, while the exact solubility characteristics of this compound in various solvents may require empirical investigation, understanding the influence of polarity, hydrogen bonding, solvent selection, and temperature can provide crucial insights into its behavior in solution.

Interesting facts

Interesting Facts about N-[(8-chlorobenzo[b][1,4]benzothiazepin-6-yl)methyl]-N',N'-dimethyl-ethane-1,2-diamine

This compound is a fascinating example of a multi-functional molecule that plays a significant role in medicinal chemistry. Here are some interesting insights:

  • Structure & Complexity: The compound encompasses a benzothiazepine core, which is a fused heterocyclic structure known for its diversity of biological activities. The presence of a chloro substituent adds to its structural uniqueness.
  • Pharmacological Potential: Benzothiazepines are often studied for their properties as antidepressants, antipsychotics, and anxiolytics. This particular compound might share similar therapeutic potential, warranting further exploration.
  • Bioavailability: Molecules like this, with dual amine groups, can interact with biological receptors, enhancing their bioavailability – a crucial aspect for drug design.
  • Research Implications: The complexity of this compound opens avenues for synthesis challenges and can lead to novel derivatives, contributing to the library of pharmacologically active substances.
  • Mechanistic Studies: Understanding how this compound interacts at the molecular level could lead to breakthroughs in treating various neurological disorders. Compounds with a similar structure often demonstrate unique mechanisms of action, making them of high interest in biomedical research.

Ultimately, N-[(8-chlorobenzo[1,4]benzothiazepin-6-yl)methyl]-N',N'-dimethyl-ethane-1,2-diamine provides a wealth of research opportunities, showcasing the intricate relationship between chemical structure and biological function. As the scientific community delves deeper into its properties, who knows what new advancements may emerge?

Synonyms
BRN 1087813
DIBENZO(b,f)(1,4)THIAZEPINE, 2-CHLORO-11-((2-DIMETHYLAMINOETHYL)METHYLAMINO)-
6550-57-8
DTXSID70215806
2-Chloro-11-((2-dimethylaminoethyl)methylamino)dibenzo(b,f)(1,4)thiazepine
DTXCID60138297