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N-(8-fluoro-9H-fluoren-2-yl)acetamide

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Identification
Molecular formula
C15H12FNO
CAS number
1698-67-3
IUPAC name
N-(8-fluoro-9H-fluoren-2-yl)acetamide
State
State

At room temperature, N-(8-fluoro-9H-fluoren-2-yl)acetamide is in a solid state. It is typically found in crystalline form.

Melting point (Celsius)
167.10
Melting point (Kelvin)
440.25
Boiling point (Celsius)
338.50
Boiling point (Kelvin)
611.65
General information
Molecular weight
227.24g/mol
Molar mass
227.2380g/mol
Density
1.3200g/cm3
Appearence

The compound appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of N-(8-fluoro-9H-fluoren-2-yl)acetamide

N-(8-fluoro-9H-fluoren-2-yl)acetamide is an intriguing compound with a unique solubility profile. Understanding its solubility is essential for applications in various chemical processes. Here are some key points to consider:

  • Solvent Compatibility: N-(8-fluoro-9H-fluoren-2-yl)acetamide tends to exhibit varying solubility in different solvents. It is generally more soluble in polar protic solvents such as methanol and ethanol, while demonstrating lower solubility in non-polar solvents.
  • Temperature Effects: As with many organic compounds, increasing temperature can enhance the solubility of N-(8-fluoro-9H-fluoren-2-yl)acetamide, making it an important consideration in experimental procedures.
  • pH Influence: The solubility can also be affected by the pH of the solution. Although specific pKa values are essential for comprehensive analysis, the compound may exhibit better solubility in acidic or basic conditions depending on the protonation state.

In summary, the solubility of N-(8-fluoro-9H-fluoren-2-yl)acetamide is influenced by a combination of solvents, temperature, and pH. Understanding these factors is critical for optimizing its use in chemical applications.

Interesting facts

Interesting Facts about N-(8-Fluoro-9H-fluoren-2-yl)acetamide

N-(8-Fluoro-9H-fluoren-2-yl)acetamide is a fascinating compound that belongs to the category of amides, characterized by the presence of the acetamide functional group. Here are some remarkable insights about this intriguing chemical:

  • Fluorine Impact: The presence of the fluorine atom at the 8-position on the fluorenyl ring significantly influences the chemical properties of this compound. Fluorine is known for its electronegativity, which can enhance the compound's stability and reactivity.
  • Pharmaceutical Relevance: Compounds like this are often investigated for their potential in medicinal chemistry, particularly in creating novel drugs, due to their unique structural properties.
  • Synthesis: The synthesis of N-(8-fluoro-9H-fluoren-2-yl)acetamide may involve various organic reactions, making it a subject of interest for synthetic chemists. Techniques such as amide formation via acylation reactions are common in this context.
  • Structure-Activity Relationship (SAR): Understanding the structure-activity relationship is crucial in organic chemistry, and this compound serves as an excellent example to study how modifications (such as fluorination) can impact biological activity.
  • Applications: Beyond medicinal applications, this compound's derivatives may have potential uses in organic electronics and materials science due to the stability imparted by the fluorenyl moiety.

As a chemistry student, appreciating such compounds as N-(8-fluoro-9H-fluoren-2-yl)acetamide opens up a deeper understanding of how molecular modifications can lead to varied functionalities, making it a valuable compound in both research and application.

Synonyms
8-Fluoro-2-faa
2823-95-2
ACETAMIDE, N-(8-FLUOROFLUOREN-2-YL)-
8-Fluoro-2-acetylaminofluorene
N-(8-fluoro-9H-fluoren-2-yl)acetamide
N-(8-Fluorofluoren-2-yl)acetamide
Acetamide, N-(8-fluoro-9H-fluoren-2-yl)-
MLS002667066
NSC-46526
NSC 46526
BRN 2738191
NSC46526
4F9GW2Y8NZ
CHEMBL84885
DTXSID50182486
HMS3088P20
WLN: L B656 HHJ EMV1 JF
SMR001556838
Acetamide,n-(8-fluoro-9h-fluoren-2-yl)-
DS-006294