Skip to main content

N-(9H-fluoren-1-yl)-N-hydroxy-acetamide

ADVERTISEMENT
Identification
Molecular formula
C15H13NO2
CAS number
143134-75-0
IUPAC name
N-(9H-fluoren-1-yl)-N-hydroxy-acetamide
State
State

At room temperature, N-(9H-fluoren-1-yl)-N-hydroxy-acetamide exists as a solid. It is stable under standard conditions and forms a crystalline powder, which makes it useful in various chemical applications.

Melting point (Celsius)
176.30
Melting point (Kelvin)
449.45
Boiling point (Celsius)
501.20
Boiling point (Kelvin)
774.35
General information
Molecular weight
225.27g/mol
Molar mass
225.2490g/mol
Density
1.3260g/cm3
Appearence

N-(9H-fluoren-1-yl)-N-hydroxy-acetamide appears as a white to off-white crystalline powder. Its color can vary slightly depending on the purity and form but is typically solid at room temperature. The compound's crystalline nature contributes to its distinct appearance.

Comment on solubility

Solubility of N-(9H-fluoren-1-yl)-N-hydroxy-acetamide

N-(9H-fluoren-1-yl)-N-hydroxy-acetamide is a compound whose solubility characteristics are influenced by its specific chemical structure and functional groups. Understanding the solubility is crucial for applications in various scientific fields.

Key Points on Solubility

  • Polarity: The presence of the N-hydroxy group often increases the polarity of the compound, potentially enhancing its solubility in polar solvents such as water.
  • Solvent Compatibility: N-(9H-fluoren-1-yl)-N-hydroxy-acetamide may show variable solubility depending on the solvent, with higher solubility likely in organic solvents like ethanol or dimethyl sulfoxide (DMSO).
  • Hydrogen Bonding: The ability to form hydrogen bonds, owing to the hydroxyl group, can promote solubility in certain environments, especially when interacting with water molecules.

It’s essential to perform empirical solubility tests to determine the exact behavior of this compound in various solvents. In practical applications, solubility is a pivotal factor, affecting how this compound may be employed in biochemical or industrial processes.

Interesting facts

Interesting Facts about N-(9H-fluoren-1-yl)-N-hydroxy-acetamide

N-(9H-fluoren-1-yl)-N-hydroxy-acetamide is a remarkable compound known for its versatile applications in the field of chemistry and beyond. Here are some intriguing aspects to consider:

  • Structural Significance: This compound features a unique combination of a fluorenyl group and a hydroxyacetamide moiety, contributing to its distinctive properties. The fluorenyl group enhances its stability and solubility in organic solvents.
  • Biological Activity: Studies indicate that N-(9H-fluoren-1-yl)-N-hydroxy-acetamide exhibits interesting biological properties, making it a subject of research for potential therapeutic applications. It is believed to play a role in various biochemical processes.
  • Synthesis Challenges: The synthesis of this compound requires intricate chemical techniques due to the complexity of the fluorenyl system. Chemists often face challenges related to regioselectivity and yield optimization during the synthesis process.
  • Potential Applications: Beyond its academic interest, N-(9H-fluoren-1-yl)-N-hydroxy-acetamide is hypothesized to be utilized in drug design and development owing to its structural features, which may influence its interaction with biological targets.
  • Research Opportunities: This compound serves as a fascinating platform for developing new derivatives that could lead to innovative solutions in medicinal chemistry. As a chemist, exploring its reactivity can yield valuable insights into structure-activity relationships.

In summary, N-(9H-fluoren-1-yl)-N-hydroxy-acetamide is more than just a chemical compound; it embodies the complexity and beauty of organic chemistry. To quote a famous chemist, "Every compound tells a story," and in the case of this molecule, the narrative is rich with potential!

Synonyms
1-Fluorenylacethydroxamic acid
N-Fluoren-1-ylacetohydroxamic acid
22251-01-0
N-Hydroxy-1-fluorenylacetamide
ACETOHYDROXAMIC ACID, N-FLUOREN-1-YL-
BRN 2131585
DTXSID80176792
RefChem:316805
DTXCID0099283
CHEMBL280245