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N,N'-Diacetylbenzylamine

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Identification
Molecular formula
C11H14N2O2
CAS number
3695-18-9
IUPAC name
N-[acetamido(phenyl)methyl]acetamide
State
State

At room temperature, N,N'-Diacetylbenzylamine is typically found in a solid state.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
317.00
Boiling point (Kelvin)
590.15
General information
Molecular weight
206.24g/mol
Molar mass
206.2370g/mol
Density
1.0000g/cm3
Appearence

N,N'-Diacetylbenzylamine typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N-[acetamido(phenyl)methyl]acetamide

N-[acetamido(phenyl)methyl]acetamide is a compound with intriguing solubility characteristics. Understanding its solubility behavior is crucial for various applications, particularly in pharmaceuticals and chemical synthesis. Here are some key points regarding its solubility:

  • Polarity: Due to the presence of acetamide functional groups, this compound exhibits a moderate level of polarity, which can influence its interaction with solvents.
  • Solvent Compatibility: It is more likely to be soluble in polar solvents such as water and dimethyl sulfoxide (DMSO), while being less soluble in non-polar solvents. This is attributed to its functional groups forming hydrogen bonds.
  • Temperature Dependence: Like many organic compounds, the solubility of N-[acetamido(phenyl)methyl]acetamide may increase with temperature, making heating a useful technique in dissolving this substance in solution.
  • Concentration: The solubility may also depend on the concentration of the compound; at higher concentrations, solubility limits can be reached quickly, resulting in precipitation.

In conclusion, the solubility of N-[acetamido(phenyl)methyl]acetamide is characterized by its ability to dissolve in polar solvents while being limited in non-polar environments. This property underlines the importance of solvent choice in applications involving this compound. As noted, “Like dissolves like,” emphasizing the significance of matching solvent polarity to achieve effective solubility.

Interesting facts

Interesting Facts about N-[Acetamido(phenyl)methyl]acetamide

N-[Acetamido(phenyl)methyl]acetamide is a compound that showcases the intriguing chemistry of amidation and the interaction of aromatic groups with amides. Here are some captivating insights:

  • Functional Groups: This molecule features amide groups, which are characterized by a nitrogen atom bonded to a carbonyl group (C=O). This makes amides important in the formation of proteins and other biologically significant molecules.
  • Role in Drug Development: Compounds like N-[Acetamido(phenyl)methyl]acetamide can serve as important intermediates in pharmaceutical synthesis. Their intricate structures often make them suitable candidates for developing new drugs.
  • Aromatic Influence: The presence of the phenyl ring not only enhances the compound's stability but also can influence its biological activity. Aromatic groups are known to interact with various biological targets, making them pivotal in medicinal chemistry.
  • Application in Research: This compound can be utilized in organic synthesis and the study of amide-related transformations, making it a valuable tool for chemists working in the field of organic and medicinal chemistry.
  • Exciting Derivatives: Due to its structure, there is potential for creating various derivatives by altering the acetamido and phenyl groups, leading to a diverse range of compounds with potentially new properties and activities.

In the words of notable chemists, *"The beauty of chemistry lies in its ability to create complex structures from simple components."* N-[Acetamido(phenyl)methyl]acetamide exemplifies this beauty through its unique composition and functional potential.

This compound not only adds to the rich tapestry of organic chemistry but also offers a glimpse into the endless possibilities of synthesis and application in various scientific fields.

Synonyms
N,N'-Benzylidenebisacetamide
N,N'-Benzylidenediacetamide
Acetamide, N,N'-(phenylmethylene)bis-
ACETAMIDE, N,N'-BENZYLIDENEBIS-
Acetamide, N,N'-benzylidenedi-
OJD1KQ9Y57
NSC 408694
BRN 2109405
AI3-15471
UNII-OJD1KQ9Y57
NSC-408694
DTXSID50219125
4-07-00-00526 (Beilstein Handbook Reference)
N,N'-(PHENYLMETHYLENE)BIS(ACETAMIDE)
N,N'-(Phenylmethylene)bis[acetamide]
DTXCID70141616
Acetamide, N,N'-(phenylmethylene)bis-(9CI)
6907-68-2
N,N'-(Phenylmethylene)diacetamide
N-(Acetylaminophenylmethyl)acetamide
N-[acetamido(phenyl)methyl]acetamide
MFCD00963253
N-(Acetylamino-phenyl-methyl)-acetamide
Benzyliden-bis-acetamid
CBMicro_026176
Acetamide,N'-benzylidenedi-
Acetamide,N'-benzylidenebis-
Oprea1_077948
Oprea1_488338
N',N'-Benzylidenebisacetamide
SCHEMBL3735283
JFUUKHUKGAQKIW-UHFFFAOYSA-N
HMS1682M10
Acetamide,N'-(phenylmethylene)bis-
Acetamide,n,n-(phenylmethylene)bis-
NSC408694
AKOS000543920
SB77504
SDCCGMLS-0064990.P001
N-[(acetylamino)(phenyl)methyl]acetamide
AS-35539
SY241615
BIM-0026041.P001
DS-006299
N-(ACETAMIDO-PHENYL-METHYL)ACETAMIDE
CS-0314613
AG-777/36179017
N,N inverted exclamation mark -(Phenylmethylene)diacetamide