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Clonazepam

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Identification
Molecular formula
C15H10ClN3O3
CAS number
1622-61-3
IUPAC name
N'-acetyl-8-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide
State
State

At room temperature, Clonazepam is typically a solid state compound.

Melting point (Celsius)
239.00
Melting point (Kelvin)
512.15
Boiling point (Celsius)
205.00
Boiling point (Kelvin)
478.15
General information
Molecular weight
315.72g/mol
Molar mass
315.7150g/mol
Density
1.6200g/cm3
Appearence

Clonazepam appears as a white to light yellow crystalline powder. It is typically odorless.

Comment on solubility

Solubility of N'-acetyl-8-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide

The solubility of N'-acetyl-8-chloro-6H-benzob[1,4]benzoxazepine-5-carbohydrazide in various solvents can vary significantly based on its chemical structure and functional groups. Here are some key points regarding its solubility:

  • Polarity: This compound is expected to have polar functional groups due to the presence of the hydrazide moiety, which may increase its solubility in polar solvents like water.
  • Solvent Interaction: It may interact favorably with solvents such as dimethyl sulfoxide (DMSO) or dimethylformamide (DMF) due to their ability to solvate polar molecules.
  • Temperature Dependency: The solubility of organic compounds often increases with temperature, thus allowing for better solubility at elevated temperatures.
  • pH Sensitivity: The solubility may alter depending on the pH of the solution, particularly if the compound can exist in ionized forms.
  • Structural Factors: Steric bulk and intermolecular forces can impact solubility; larger groups may hinder interaction with solvent molecules.

In conclusion, while predicting the exact solubility requires experimental data, understanding the molecular structure and potential interactions with solvents offers insight into its solubility behavior. As with many organic compounds, solubility profiles can be both straightforward and complex, influenced by a combination of factors.

Interesting facts

Interesting Facts about N'-Acetyl-8-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide

N'-acetyl-8-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide is a fascinating compound that attracts the interest of chemists due to its unique structure and potential applications.

Key Characteristics:

  • Structural Complexity: This compound features a complex heterocyclic architecture that incorporates both benzene and oxazepine rings, providing a rich chemical space for interaction.
  • Pharmacological Interest: Compounds of this type are often examined for their biological activities. Researchers explore their potential utility as pharmaceuticals due to their intricate molecular frameworks.
  • Functional Groups: The presence of an acetyl group and a chloro atom significantly influences the compound's reactivity and solubility, potentially enhancing its interaction with biological targets.

One of the intriguing aspects of N'-acetyl-8-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide is its role in the development of new therapeutic agents. As with many heterocyclic compounds, they can serve as scaffolds for drug design. As William H. B. Pullman once said, "The chemistry of life is the chemistry of the carbon compounds." This emphasizes the importance of such complex compounds in drug development.

In synthetic chemistry, creating compounds with such diverse functional groups can also provide insights into reaction mechanisms and the behavior of different chemical moieties under various conditions. Future studies may unravel even more about this compound's properties and potential applications, making it an exciting subject of research.

Synonyms
Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide
DTXSID10941091
DTXCID301369537
RefChem:920035
N'-acetyl-8-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide
PDSP1_001724
PDSP2_001707
L000545