Skip to main content

N-Acetyl-N-propylacetamide

ADVERTISEMENT
Identification
Molecular formula
C7H13NO2
CAS number
20227-89-0
IUPAC name
N-acetyl-N-propyl-acetamide
State
State

At room temperature, N-acetyl-N-propylacetamide is typically a liquid.

Melting point (Celsius)
-42.00
Melting point (Kelvin)
231.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
143.19g/mol
Molar mass
143.2080g/mol
Density
0.9815g/cm3
Appearence

N-Acetyl-N-propylacetamide is a clear, colorless liquid. It can also sometimes appear as a slightly yellowish liquid depending on the level of purity.

Comment on solubility

Solubility of N-acetyl-N-propyl-acetamide

N-acetyl-N-propyl-acetamide, often referred to in shorthand as NAPA, is an intriguing compound when it comes to its solubility characteristics. This compound is primarily known for its amide functional groups which play a significant role in determining its interactions with solvents.

Key Points on Solubility:

  • Polar Characteristics: As an amide, N-acetyl-N-propyl-2-acetamide possesses polar bonds due to the presence of carbonyl and nitrogen moieties.
  • Solvent Compatibility: It generally exhibits good solubility in polar solvents such as water, ethanol, and methanol. This is primarily attributed to hydrogen bonding capabilities.
  • Limitations: However, its solubility in non-polar solvents (e.g., hexane, toluene) is limited, which can pose challenges in certain applications.

“Like dissolves like” is a commonly used principle in chemistry to predict solubility. In the case of N-acetyl-N-propyl-acetamide, its polar nature aligns well with polar solvents, fostering favorable interactions that enhance its solubility profile.

This compound's distinctive solubility properties make it a significant contender in the fields of pharmaceuticals and chemical synthesis, where precise solvent interactions are crucial for successful reactions.

Interesting facts

Interesting Facts about N-acetyl-N-propyl-acetamide

N-acetyl-N-propyl-acetamide, a fascinating compound in the realm of organic chemistry, belongs to the family of amides. Understanding its properties, synthesis, and potential applications can deepen our appreciation for this intriguing substance.

Key Characteristics

  • Chemical Structure: As an amide, N-acetyl-N-propyl-acetamide features a carbonyl group (C=O) linked to a nitrogen atom, suggesting potential for intriguing reactivity and bonding characteristics.
  • Synthesis: This compound can be synthesized through reactions involving acetic anhydride and propylamine, showcasing the versatility of amides in organic synthesis.

Applications and Uses

  • Pharmaceutical Chemistry: N-acetyl-N-propyl-acetamide can be investigated for its biological properties, especially in drug development as amides often exhibit significant pharmacological activities.
  • Industrial Relevance: Amides are commonly used in the production of polymers and as solvents in various chemical processes, indicating its potential role in manufacturing.

Scientific Significance

As noted in scholarly articles, "the structural diversity of amides provides a rich tapestry for research within medicinal chemistry." Therefore, studying compounds like N-acetyl-N-propyl-acetamide can open doors to innovative pharmaceutical strategies and applications.

The compound also encourages exploration among chemistry students as they learn about functional groups and their transformations, inspiring further curiosity in the study of organic compounds. Whether it's through hands-on laboratory experiments or theoretical discussions, N-acetyl-N-propyl-acetamide exemplifies the fascinating complexity found in chemical research.

Synonyms
N-ACETYL-N-PROPYLACETAMIDE
1563-84-4
Acetamide, N-acetyl-N-propyl-
Diacetamide, N-propyl-
AI3-28893
EINECS 216-355-1
N-Acetyl-n-propylacetamide #
SCHEMBL11408090
DTXSID80166072
NS00025076