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N-Acetylphenylalanylamide

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Identification
Molecular formula
C12H16N2O2
CAS number
1452-06-4
IUPAC name
N-(acetylcarbamoyl)-2-phenyl-butanamide
State
State

At room temperature, N-(acetylcarbamoyl)-2-phenyl-butanamide is typically in a solid state, due to its crystalline structure and relatively high melting point.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
426.80
Boiling point (Kelvin)
699.95
General information
Molecular weight
206.27g/mol
Molar mass
206.2460g/mol
Density
1.1965g/cm3
Appearence

N-(acetylcarbamoyl)-2-phenyl-butanamide is generally a white to off-white crystalline solid. The solid may also appear as a powder and is usually odorless.

Comment on solubility

Solubility of N-(acetylcarbamoyl)-2-phenyl-butanamide (C12H16N2O2)

N-(acetylcarbamoyl)-2-phenyl-butanamide, a compound with a complex structure, exhibits solubility behavior that is notable in various solvents. Understanding its solubility characteristics is crucial for its application in different chemical processes. Here are some points to consider:

  • Polar Solvents: The presence of amide and carbonyl groups in the structure often enhances solubility in polar solvents such as water and methanol due to hydrogen bonding interactions.
  • Non-Polar Solvents: Conversely, due to its phenyl group, this compound may have limited solubility in non-polar solvents like hexane and cyclohexane.
  • Temperature Dependency: Solubility can also vary significantly with temperature, often increasing as temperature rises, reflecting the kinetic factors influencing dissolution.
  • pH Influence: The pH of the solution may also affect solubility, particularly if ionization of functional groups occurs at extreme pH levels, potentially enhancing or inhibiting solubility.

In summary, N-(acetylcarbamoyl)-2-phenyl-butanamide displays variable solubility depending on factors such as solvent polarity, temperature, and pH. The interplay of these factors is essential to explore for optimal practical applications, making a comprehensive solubility profile vital. As solubility plays a key role in processes such as drug delivery and formulation, understanding these elements enhances the compound's usability.

Interesting facts

Exploring N-(Acetylcarbamoyl)-2-phenyl-butanamide

N-(acetylcarbamoyl)-2-phenyl-butanamide, often appreciated for its intriguing structural and functional properties, is a compound that demonstrates the complexity of organic molecules. It belongs to the class of amides, which are known for their prevalence in both organic chemistry and biological systems. Here are some interesting aspects of this compound:

  • Versatile Applications: Compounds like N-(acetylcarbamoyl)-2-phenyl-butanamide are often used in pharmaceuticals. They can exhibit a variety of biological activities, making them promising candidates for drug development.
  • Structural Significance: The presence of the phenyl group offers the ability to engage in π-π stacking interactions, which can influence the compound's melting and boiling points, and its reactivity in chemical reactions.
  • Functional Groups: This compound contains both an acetyl group and a carbamoyl group. The acetyl group can assist in enhancing lipophilicity, which may improve the bioavailability of the compound in medicinal chemistry.
  • Chirality: The butanamide structure introduces a degree of stereochemistry, which could lead to the formation of enantiomers. This chirality is particularly important in drug development, as different enantiomers can have vastly different biological effects.

As John Kenneth Galbraith stated, "The only function of economic forecasting is to make astrology look respectable." Similarly, the world of organic compounds is filled with the mystique and unpredictability of how slight modifications can lead to vastly different properties and activities. Understanding compounds like N-(acetylcarbamoyl)-2-phenyl-butanamide is essential for unlocking new avenues in research and application.

In summary, the exploration of N-(acetylcarbamoyl)-2-phenyl-butanamide is not just a chemical pursuit but a journey into the heart of organic compounds that shape our world. As we delve deeper into its properties and to what extent it can be utilized, the scientific community stands on the brink of potential advancements that can stem from this intriguing molecule.

Synonyms
acetylpheneturide
Crampol
Crampole
13402-08-9
1-Acetyl-3-(2-phenylbutyryl)urea
Acetylpheneturide [JAN]
1-Acetyl-3-phenylethylacetylurea
N-(acetylcarbamoyl)-2-phenylbutanamide
Urea, 1-acetyl-3-(2-phenylbutyryl)-
P-398
EINECS 236-493-6
Crampol (TN)
BRN 1987746
N-alpha-Ethylphenylacetyl-N'-acetyl urea
DTXSID8048789
UNII-G083008IJ0
N-[(ACETYLAMINO)CARBONYL]-2-PHENYLBUTANAMIDE
Acetylpheneturide (JAN)
G083008IJ0
N-((Acetylamino)carbonyl)-alpha-ethylbenzeneacetamide
ACETYLPHENETURIDE [MI]
DTXCID8028715
ACETYLPHENETURIDE [WHO-DD]
1-Acetyl-3-(phenylethylacetyl)urea
N-((Acetylamino)carbonyl)-.alpha.-ethylbenzeneacetamide
NCGC00182986-01
Benzeneacetamide, N-[(acetylamino)carbonyl]-.alpha.-ethyl-
N-.alpha.-Ethylphenylacetyl-N'-acetylurea
N-((Acetylamino)carbonyl)-2-phenylbutanamide
(+/-)-1-ACETYL-3-(2-PHENYLBUTYRYL)UREA
N-[(Acetylamino)carbonyl]-alpha-ethylbenzeneacetamide
SCHEMBL79701
CHEMBL93018
CHEBI:31166
Tox21_113266
N-Acetyl-N'-(2-phenylbutanoyl)urea #
N-alpha-Ethylphenylacetyl-N'-acetylurea
CAS-13402-08-9
NS00010539
D01409
Q27278420
Benzeneacetamide, N-((acetylamino)carbonyl)-alpha-ethyl-
236-493-6