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N-phenylformamide

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Identification
Molecular formula
C7H7NO
CAS number
103-70-8
IUPAC name
N-anilinoformamide
State
State

At room temperature, N-phenylformamide can exist as a liquid or low-melting solid. It is primarily used in solid form for many chemical reactions and applications.

Melting point (Celsius)
47.00
Melting point (Kelvin)
320.15
Boiling point (Celsius)
238.00
Boiling point (Kelvin)
511.15
General information
Molecular weight
121.14g/mol
Molar mass
121.1420g/mol
Density
1.1319g/cm3
Appearence

N-phenylformamide is a colorless to pale yellow solid or liquid, depending on temperature and purity. It is characterized by a distinctive aromatic odor due to the presence of the phenyl group.

Comment on solubility

Solubility of N-anilinoformamide

N-anilinoformamide, with its unique chemical structure, exhibits specific solubility characteristics that are crucial in various applications. Here are some key insights into its solubility:

  • Water Solubility: N-anilinoformamide demonstrates moderate solubility in water. The presence of both an amine and a carbonyl group enables it to engage in hydrogen bonding with water molecules, enhancing its ability to dissolve.
  • Solvent Compatibility: It is more soluble in polar organic solvents such as alcohols and acetonitrile. This compatibility is advantageous in organic synthesis and chemical reactions.
  • Temperature Influence: Like many organic compounds, the solubility of N-anilinoformamide can increase with temperature. This is particularly important during synthesis or extraction processes.
  • Concentration Effects: Higher concentrations may lead to reduced solubility owing to molecular interactions. Care should be taken when preparing solutions to ensure optimal solubility.

In summary, N-anilinoformamide's solubility profile makes it a versatile compound in the realm of chemistry. As the saying goes, "like dissolves like," and understanding these solubility traits can unlock numerous synthetic pathways and improve application efficiency.

Interesting facts

Interesting Facts about N-anilinoformamide

N-anilinoformamide is an intriguing organic compound with several noteworthy aspects that make it an interesting subject for both scientists and students of chemistry.

Chemical Structure and Composition

This compound consists of an aniline group connected to a formamide functional group. The presence of both an aromatic amine and the formyl group makes N-anilinoformamide a fascinating hybrid structure, exhibiting unique chemical properties.

Applications in Research and Industry

  • Pharmaceutical Development: N-anilinoformamide is often utilized in the synthesis of various pharmaceutical compounds, showcasing its significance in medicinal chemistry.
  • Agricultural Chemicals: It may also play a role in the development of agrochemicals, helping to improve crop yields and protect against pests.
  • Materials Science: Its derivatives are explored in materials research for the development of polymers and other advanced materials.

Reactivity and Chemical Behavior

The compound behaves as a polar molecule, leading to interesting reactivity patterns. Its amine and formamide groups can participate in a variety of reactions such as:

  • Hydrogen bonding interactions, contributing to solubility in polar solvents.
  • Electrophilic substitution reactions, particularly on the aromatic ring, which opens up pathways for the synthesis of more complex molecules.
  • Reactions with electrophiles, which is crucial for functionalization in organic synthesis.

Cultural and Historical Context

Interestingly, the study of amides and their derivatives, including N-anilinoformamide, has historical significance in organic chemistry. The exploration of amide bonds has paved the way for advancements in peptide chemistry and biotechnology, ultimately leading to the design of new therapeutics and diagnostics.

In conclusion, N-anilinoformamide is more than just a simple compound; it embodies the intersection of theoretical chemistry and practical application. Its unique structure and versatile reactivity make it a valuable compound for scientific inquiry and advancements across various fields.

Synonyms
1-Formyl-2-phenylhydrazine
622-84-4
N'-phenylformohydrazide
Hydrazinecarboxaldehyde, 2-phenyl-
N-anilinoformamide
Formic acid, 2-phenylhydrazide
HYDRAZINE, 1-FORMYL-2-PHENYL-
N'-Formyl-N-phenylhydrazine
N'-phenylcarbohydrazide
N-Formylfenylhydrazin
2-Formyl-1-phenylhydrazine
Fenylhydrazid kyseliny mravenci
NSC 122444
NSC 406126
N'-Phenylformic hydrazide
1-Phenyl-2-formylhydrazine
VE4U62H7IL
NSC-122444
NSC-406126
WLN: VHMMR
N-Formylfenylhydrazin [Czech]
2-Phenylhydrazine-1-carboxaldehyde
Fenylhydrazid kyseliny mravenci [Czech]
BRN 0956804
2-Phenylhydrazinecarboxaldehyde
AI3-01558
MFCD00043517
Ameisensaure-phenylhydrazid
UNII-VE4U62H7IL
NCIOpen2_003649
N'-Phenylformic hydrazide #
3-15-00-00154 (Beilstein Handbook Reference)
SCHEMBL243768
DTXSID50211245
AAA62284
BCP27079
NSC122444
NSC406126
(.BETA.-FORMYLPHENYL)HYDRAZINE
AKOS004907806
SB86019
DB-054117
CS-0243439
EN300-263667
G31126
Z1198148433