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N'-benzoyl-4-fluoro-benzohydrazide

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Identification
Molecular formula
C14H11FN2O2
CAS number
102971-29-1
IUPAC name
N'-benzoyl-4-fluoro-benzohydrazide
State
State

N'-benzoyl-4-fluoro-benzohydrazide is typically observed as a solid under standard conditions of temperature and pressure.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
258.25g/mol
Molar mass
258.2530g/mol
Density
1.2980g/cm3
Appearence

N'-benzoyl-4-fluoro-benzohydrazide typically appears as an off-white to pale-yellow crystalline solid. The crystals may vary slightly in color depending on purity and exposure to light.

Comment on solubility

Solubility of N'-benzoyl-4-fluoro-benzohydrazide

N'-benzoyl-4-fluoro-benzohydrazide, with its unique structure, showcases specific solubility characteristics that are worth exploring. Understanding the solubility of this compound in various solvents can provide valuable insights into its behavior in different chemical environments.

Generally, the solubility of N'-benzoyl-4-fluoro-benzohydrazide can be influenced by several factors:

  • Polarity of Solvent: The compound is relatively non-polar due to the presence of the benzoyl and fluorobenzene groups, which may limit its solubility in polar solvents like water.
  • Functional Groups: The presence of hydrazide functional groups may enhance solubility in polar protic solvents like ethanol or methanol.
  • Temperature Effects: Generally, solubility increases with temperature, so heating the solvent may facilitate the dissolution of the compound.

As with many organic compounds, while it may not be readily soluble in water, it often exhibits better solubility in organic solvents such as:

  • Dichloromethane
  • Acetone
  • Ethyl acetate

In summary, the solubility of N'-benzoyl-4-fluoro-benzohydrazide demonstrates a complex interplay of chemical properties and solvent interactions. As one would typically expect, a deeper investigation into these solubility behaviors can aid in practical applications and further research endeavors.

Interesting facts

Interesting Facts about N'-benzoyl-4-fluoro-benzohydrazide

N'-benzoyl-4-fluoro-benzohydrazide is a fascinating compound that showcases the intricate world of organic chemistry. This compound is part of the hydrazide class, which has garnered attention due to its diverse biological activities and applications in various fields. Here are some notable points:

  • Structure & Functionality: The compound features both a benzoyl group and a fluorine substituent, enhancing its chemical reactivity and biological interactions. This unique structure can lead to interesting physicochemical properties.
  • Pharmaceutical Potential: Hydrazides, including N'-benzoyl-4-fluoro-benzohydrazide, have shown promise in medicinal chemistry. They often exhibit antibacterial and antifungal activities, making them valuable in drug development.
  • Fluorine’s Impact: The presence of the fluorine atom in the structure can significantly influence the compound's metabolic stability and lipophilicity, which are crucial for its effectiveness as a pharmaceutical agent.
  • Research Insights: Studies have increasingly focused on the modification of hydrazide compounds to enhance their biological efficacy. N'-benzoyl-4-fluoro-benzohydrazide serves as a critical substrate for synthesizing various derivatives that might possess stronger therapeutic effects.
  • Applications in Scientific Research: Besides medicinal applications, this compound is also explored in synthetic organic chemistry as an intermediate for the preparation of other complex organic compounds.

In conclusion, N'-benzoyl-4-fluoro-benzohydrazide stands out as a compound with substantial potential, not only in therapeutic applications but also as a key player in chemical synthesis. As research in this field evolves, we are likely to uncover even more exciting uses for this versatile compound.

Synonyms
BENZOIC ACID, p-FLUORO-, BENZOYLHYDRAZIDE
732-95-6
BRN 2622294
1-Benzoyl-2-(p-fluorobenzoyl)hydrazine
1-Benzoyl-2-(4-fluorobenzoyl)hydrazine
Hydrazine, 1-benzoyl-2-(p-fluorobenzoyl)-
DTXSID40223438
DTXCID40145929
654-570-6
4-fluoro-N'-(phenylcarbonyl)benzohydrazide
N'-benzoyl-4-fluorobenzohydrazide
STK015492
AKOS002968068
N'-(4-FLUOROBENZOYL)BENZOHYDRAZIDE