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Tacrine

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Identification
Molecular formula
C13H14N2
CAS number
321-64-2
IUPAC name
N-benzyl-1,2,3,4-tetrahydroacridin-9-amine
State
State

At room temperature, Tacrine is a solid compound usually found in the form of a crystalline powder.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.00
Boiling point (Celsius)
440.00
Boiling point (Kelvin)
713.00
General information
Molecular weight
198.27g/mol
Molar mass
198.2600g/mol
Density
1.2100g/cm3
Appearence

Tacrine is typically a white to off-white crystalline powder. It is odorless or may have a slight odor characteristic of its chemical nature.

Comment on solubility

Solubility of N-benzyl-1,2,3,4-tetrahydroacridin-9-amine (C13H14N2)

The solubility of N-benzyl-1,2,3,4-tetrahydroacridin-9-amine, commonly characterized by its organic amine structure, can be influenced by several factors. Here are some key points to consider:

  • Polarity: As an organic compound, N-benzyl-1,2,3,4-tetrahydroacridin-9-amine exhibits moderate polarity due to the presence of amine groups.
  • Solvents: It is expected to be more soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO) than in water.
  • Hydrogen Bonding: The amine functionality allows for potential hydrogen bonding interactions, which can enhance solubility in polar solvents.
  • Factors Affecting Solubility: Temperature and pH can also play roles in solubilizing N-benzyl-1,2,3,4-tetrahydroacridin-9-amine, with higher temperatures generally increasing solubility.

In summary, while N-benzyl-1,2,3,4-tetrahydroacridin-9-amine has limited solubility in water, its organic nature suggests better solubility in various organic solvents. "Like dissolves like" is a useful phrase here; understanding the solvent properties will be crucial in predicting its behavior in solution.

Interesting facts

Interesting Facts about N-benzyl-1,2,3,4-tetrahydroacridin-9-amine

N-benzyl-1,2,3,4-tetrahydroacridin-9-amine is an intriguing chemical compound that has garnered interest in various fields of research. Here are some compelling facts about this fascinating compound:

  • Pharmacological Potential: This compound is known for its potential applications in the pharmaceutical industry, particularly in the development of drugs targeting neurological conditions and cognitive disorders.
  • Structural Diversity: The distinct tetrahydroacridine framework in its structure allows for significant diversity in modifications, making it a versatile candidate for drug design.
  • Chiral Centers: The presence of chiral centers in N-benzyl-1,2,3,4-tetrahydroacridin-9-amine introduces the possibility of creating enantiomers, which can exhibit different biological activities.
  • Research Implications: Studies indicate that compounds like this one may enhance cholinergic function, offering promising avenues in treating Alzheimer's disease and other cognitive impairments.
  • Natural Inspiration: The inspiration for such compounds often comes from nature, demonstrating how organic synthesis can mimic naturally occurring biological molecules.

As a student of chemistry, examining the synthesis and characteristics of N-benzyl-1,2,3,4-tetrahydroacridin-9-amine can expand your understanding of organic compounds and their potential applications. Furthermore, the ongoing research into its pharmacological properties highlights the vital role that organic chemists play in drug discovery and development.

In the grander scheme of things, such compounds remind us that chemistry is not merely about studying substances; it's about discovering possibilities and addressing global health challenges.

Synonyms
9-N-PHENYLMETHYLAMINO-TACRINE
N-benzyl-1,2,3,4-tetrahydroacridin-9-amine
9-(3-phenylmethylamino)-1,2,3,4-tetrahydroacridine
CHEMBL215344
SCHEMBL3366446
BDBM199182
DB03672
PD006714
9-benzylamino-1,2,3,4-tetrahydroacridine
NS00069479
N-benzyl-1,2,3,4-tetrahydroacridin-9-amine (8a)
Q27094588
9-Acridinamine, 1,2,3,4-tetrahydro-N-(phenylmethyl)-