Skip to main content

N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine

ADVERTISEMENT
Identification
Molecular formula
C11H15Cl2N
CAS number
102-97-6
IUPAC name
N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine
State
State

At room temperature, N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine is in a liquid state.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
290.70
Boiling point (Kelvin)
563.85
General information
Molecular weight
204.15g/mol
Molar mass
204.1150g/mol
Density
1.1000g/cm3
Appearence

N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine typically appears as a colorless to pale yellow liquid. It is often found in a liquid state at room temperature.

Comment on solubility

Solubility of N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine

N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine, with the chemical formula C11H15Cl2N, exhibits selective solubility characteristics due to its molecular structure. Here are some key points regarding its solubility:

  • Polarity: The presence of chlorine atoms and the amine group in the structure contributes to its polarity, which influences solubility in polar solvents.
  • Solvent Compatibility: This compound tends to be more soluble in organic solvents such as ethanol, methanol, and acetone compared to water, due to its hydrophobic benzyl group.
  • Aqueous Solubility: Solubility in water is limited. The chloride substituents can create some interactions; however, the overall solubility remains low.
  • Temperature Effect: Increasing temperature can enhance solubility in specific organic solvents, as solute-solvent interactions increase with kinetic energy.
  • Practical Implications: Understanding its solubility profile is essential for applications in drug formulation and environmental chemistry.

In summary, N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine displays relatively limited solubility in aqueous environments, while demonstrating greater solubility in organic media. This characteristic is vital for determining its behavior in various chemical contexts.

Interesting facts

Interesting Facts about N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine

N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine is a compound that piques the curiosity of chemists due to its unique structural features and potential applications. Here are some notable points of interest:

  • Chemical Structure: The compound features both benzyl and chloroethyl groups, which can influence its chemical reactivity and biological activity significantly. This combination often leads to intriguing interactions with biological systems.
  • Potential Biological Activity: Given its structure, N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine may exhibit pharmacological properties. Compounds with similar structures have been explored for their roles as antitumor agents or in neuropathic pain management.
  • Synthesis and Reactions: The synthesis of this compound can be achieved through various methods. The incorporation of chloro groups can enhance electrophilicity, making it a target for nucleophilic attacks, which is a fascinating area of study in organic synthesis.
  • Safety Considerations: The presence of chlorine atoms in its structure indicates the need for caution. Compounds containing halogens might pose hazards, and safety protocols should be strictly followed during handling and experimentation.
  • Research Applications: This compound holds potential for further research in medicinal chemistry. It can serve as a starting point for the development of novel pharmaceuticals, particularly in creating derivatives with improved efficacy and selectivity.

The exploration of N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine opens doors to understanding its synthesis, reactivity, and biological implications, making it a captivating subject for both seasoned chemists and enthusiastic chemistry students alike.

Synonyms
55-51-6
N,N-Bis(2-chloroethyl)benzenemethanamine
N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine
N-Benzylnormechlorethamine
N,N-Bis(2-chloroethyl)benzylamine
Benzenemethanamine, N,N-bis(2-chloroethyl)-
Bis(2-chloroethyl)benzylamine
benzylbis(2-chloroethyl)amine
Benzylbis(beta-chloroethyl)amine
Benzyl nor-mechlorethamine
TL 695
N-Benzyl-N,N-bis(2-chloroethyl)amine
Di-(2-chloroethyl)-benzylamine
JDX1MEP6TI
UNII-JDX1MEP6TI
BRN 2099546
BENZYLAMINE, N,N-BIS(2-CHLOROETHYL)-
DTXSID40203533
4-12-00-02164 (Beilstein Handbook Reference)
N-Benzyl-2-chloro-N-(2-chloroethyl)ethan-1-amine
BIS(2-CHLOROETHYL)BENZYLAMINE, N,N-
MFCD00196089
Benzyl-bis-(2-chloro-ethyl)-amine
N,N-bis-(2-chloroethyl)benzylamine
SCHEMBL373667
bis(2-chloroethyl)-benzylamine
benzyl-bis-(2-chloroethyl)amine
bis-(2-chloroethyl)benzyl amine
Benzyl[bis(2-chloroethyl)]amine
DTXCID70126024
N-benzyl bis(2-chloroethyl)amine
bis-(2-chloro-ethyl)benzyl amine
bis-(2chloro-ethyl)-benzyl amine
VLWJKVNMRMHPCC-UHFFFAOYSA-N
bis-(2-chloro-ethyl)-benzyl amine
bis-(2-chloro-ethyl)- benzyl amine
STL087617
AKOS002313318
DB-007717
CS-0119938
NS00033332
A1-01286
Q27281463