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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-benzyl-2-(diethylamino)-N-(m-tolyl)acetamide
State
State

At room temperature, lidocaine is typically a solid. It is often dispensed in its hydrochloride form, which is water-soluble and offers an aqueous solution for clinical use, particularly in its role as a local anesthetic.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence

Lidocaine typically appears as a colorless or slightly yellow, crystalline solid. It is readily soluble in water, which results in a clear solution.

Comment on solubility

Solubility of N-benzyl-2-(diethylamino)-N-(m-tolyl)acetamide

N-benzyl-2-(diethylamino)-N-(m-tolyl)acetamide, also known for its complex structure, demonstrates some interesting solubility characteristics. Primarily, the solubility of this compound can be influenced by several factors:

  • Polarity: The presence of both aromatic and aliphatic groups suggests a moderate polarity. It tends to dissolve well in polar organic solvents.
  • Hydrophobic interactions: The benzyl and toluidine components contribute to hydrophobic interactions that may enable solubility in non-polar solvents. Therefore, its solubility can be increased with the right solvent choice.
  • Temperature: As with many organic compounds, increasing the temperature tends to enhance solubility due to increased molecular movement, allowing for better interactions between solute and solvent.
  • pH levels: The presence of basic amino groups can lead to varying solubility based on the pH of the solution, as these groups may become protonated at lower pH levels, altering solubility behavior.

In practice, it is essential to quote: "The solubility of N-benzyl-2-(diethylamino)-N-(m-tolyl)acetamide in different solvents showcases the fascinating interplay of its molecular structure with solvent properties." When considering applications, understanding these solubility dynamics can be crucial for effectively utilizing this compound in various chemical processes.

Interesting facts

Interesting Facts about N-benzyl-2-(diethylamino)-N-(m-tolyl)acetamide

N-benzyl-2-(diethylamino)-N-(m-tolyl)acetamide is a fascinating compound that belongs to the class of acetamides, which have garnered significant attention in the field of medicinal chemistry. This compound is particularly noteworthy for its potential applications in pharmacology and drug design.

Key Features:

  • Pharmacological Potential: Compounds like N-benzyl-2-(diethylamino)-N-(m-tolyl)acetamide are often investigated for their ability to act as analgesics, which are substances that help relieve pain. Their unique structural characteristics may influence their interaction with biological targets.
  • Structural Variability: The presence of both diethylamino and m-tolyl moieties allows for a diverse range of chemical reactivity. This variability can lead to different pharmacological effects, making it an exciting area for research.
  • Research Applications: This compound is used as a key intermediate in the synthesis of other complex molecules and can play a significant role in the development of new therapeutic agents.
  • Mechanism of Action: Understanding how N-benzyl-2-(diethylamino)-N-(m-tolyl)acetamide interacts with cellular pathways is crucial. Research may focus on its receptor-binding affinities and downstream effects.

Moreover, the study of compounds like this one follows a continuous cycle of discovery, development, and application in various medical fields. As researchers unravel the complexities of such chemical structures, they contribute to advancing our knowledge of drug design and therapeutic efficacy. Ultimately, the potential of N-benzyl-2-(diethylamino)-N-(m-tolyl)acetamide serves as a reminder of the intricate relationships between chemical structure and biological function, paving the way for novel treatments in the future.