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N'-benzyl-2,2-dimethyl-propanehydrazide

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Identification
Molecular formula
C12H18N2O
CAS number
4560-00-5
IUPAC name
N'-benzyl-2,2-dimethyl-propanehydrazide
State
State
The compound is generally found as a solid at room temperature. It may become a liquid when heated above its melting point.
Melting point (Celsius)
65.00
Melting point (Kelvin)
338.20
Boiling point (Celsius)
315.50
Boiling point (Kelvin)
588.60
General information
Molecular weight
206.30g/mol
Molar mass
206.2950g/mol
Density
1.0374g/cm3
Appearence

N'-benzyl-2,2-dimethyl-propanehydrazide typically appears as a white to off-white solid, although its precise form can depend on the method of preparation and purity. The compound may be presented in a crystalline form and is known for its organic chemical characteristics.

Comment on solubility

Solubility of N'-benzyl-2,2-dimethyl-propanehydrazide

N'-benzyl-2,2-dimethyl-propanehydrazide is an organic compound that exhibits distinct solubility characteristics which can greatly affect its applications and interactions in various environments. Understanding its solubility is essential for both practical and theoretical implications in chemistry.

Solubility Insights:

  • Solvent Dependency: The solubility of this compound can significantly vary depending on the choice of solvent. Generally, organic compounds like this hydrazide are more soluble in organic solvents such as ethanol, acetone, and dichloromethane.
  • Polar vs Nonpolar: Due to the hydrophobic nature of the benzyl group, N'-benzyl-2,2-dimethyl-propanehydrazide typically shows limited solubility in polar solvents, making it less likely to dissolve in water and other polar solvents.
  • Concentration Effects: The solubility can also depend on concentration; as the concentration increases, some compounds may exhibit different dissolution behaviors, which is a critical factor in preparing solutions for synthesis or reactions.

As a summary, while it may be tempting to consider all hydrazides as having similar solubility profiles, N'-benzyl-2,2-dimethyl-propanehydrazide stands out due to its unique chemical structure that influences its affinity for various solvents. Therefore, when working with this compound, it is crucial to test solubility experimentally under the desired conditions for accurate and reproducible results.

Interesting facts

Interesting Facts about N'-benzyl-2,2-dimethyl-propanehydrazide

N'-benzyl-2,2-dimethyl-propanehydrazide is a fascinating compound with various applications in both organic synthesis and biological chemistry. Here are some interesting insights:

  • Structural Features: This compound contains a hydrazide functional group, which is known for its reactivity and ability to form various derivatives. The presence of the benzyl and dimethyl groups contributes to the compound's unique properties.
  • Applications: N'-benzyl-2,2-dimethyl-propanehydrazide is often utilized in the synthesis of pharmaceuticals and agrochemicals. Its hydrazide structure can participate in condensation reactions, making it a valuable intermediate.
  • Biological Significance: Research has indicated that hydrazides like N'-benzyl-2,2-dimethyl-propanehydrazide might exhibit antitumor, antibacterial, and antifungal activities, which makes them of great interest in medicinal chemistry.
  • Reactivity: This compound can engage in various reactions such as hydrazone formation with aldehydes and ketones, facilitating the development of new chemical entities.
  • In Literature: The importance of hydrazides is frequently highlighted in scientific literature, where they are associated with different mechanisms of action in biological systems. As one study noted, "Hydrazides represent a broad and versatile scaffold..."

With its intriguing structure and potential applications, N'-benzyl-2,2-dimethyl-propanehydrazide serves as an exciting subject of study for both chemists and students interested in organic synthesis and drug discovery.

Synonyms
PIVHYDRAZINE
Pivalylbenzhydrazine
N'-Benzylpivalohydrazide
306-19-4
Betamezid
Betamezide
Tersavide
Pivazid
Pivaloylbenzylhydrazine
Pivhydrazine [BAN]
N'-benzyl-2,2-dimethylpropanehydrazide
Pivalyl benzylhydrazine
N-Benzyl pivalhydrazide
2'-Benzylpivalohydrazide
Pivolinsaeure-N'-benzylhydrazid
UNII-TK1T520ASG
EINECS 206-180-9
BRN 0744565
Pivalic acid, 2-benzylhydrazide
TK1T520ASG
Propanoic acid, 2,2-dimethyl-, 2-(phenylmethyl)hyrazide
PIVALYLBENZHYDRAZINE [MI]
DTXSID50184667
Tersavid
Pivazide
Ro 4-1634
CBDivE_000207
1-Pivaloyl-2-benzyl-hydrazin
SCHEMBL149084
2,2-Dimethylpropanoic acid 2-(phenylmethyl)hydrazide
pivalic acid 2-benzylhydrazide
CHEMBL2106941
SCHEMBL20394102
DTXCID90107158
CHEBI:134868
AKOS016033535
DB09252
DA-76016
HY-148158
CS-0613908
NS00005903
EN300-9546535
SR-01000883696
Q7199626
SR-01000883696-1
206-180-9