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N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide

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Identification
Molecular formula
C17H18ClN3O2
CAS number
342073-80-5
IUPAC name
N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide
State
State

At room temperature, N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide is typically found in a solid state.

Melting point (Celsius)
185.50
Melting point (Kelvin)
458.70
Boiling point (Celsius)
508.10
Boiling point (Kelvin)
781.30
General information
Molecular weight
330.80g/mol
Molar mass
330.7990g/mol
Density
1.3167g/cm3
Appearence

The compound typically appears as a crystalline solid, which can range in color from white to off-white. The exact appearance can vary depending on the purity and specific form of the compound.

Comment on solubility

Solubility of N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide

The solubility of N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide, a member of the hydrazine class, is influenced by several factors:

  • Polarity: The presence of polar functional groups, such as the hydrazine and amide groups, enhances its solubility in polar solvents.
  • Hydrogen Bonding: This compound can form hydrogen bonds, which can increase its solubility in water to some extent.
  • Hydrophobic Interactions: The benzyl and chlorobenzoyl groups are hydrophobic, which might limit its solubility in water while promoting solubility in organic solvents.
  • pH Dependency: The solubility may also vary with pH, as ionization of the amide group can occur under certain conditions.

In summary, N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide is expected to have moderate solubility in water, while exhibiting greater solubility in organic solvents due to its structural characteristics. Understanding these solubility dynamics can be essential for its applications in chemical synthesis and pharmaceutical formulations.

Interesting facts

Interesting Facts about N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide

N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide is a fascinating compound that falls within the category of hydrazone derivatives and has shown intriguing properties in various fields of research. Here are some interesting aspects:

  • Pharmaceutical Potential: This compound has piqued the interest of medicinal chemists due to its potential applications as an active pharmaceutical ingredient (API). Its unique structure allows for enhanced interactions with biological targets, making it a candidate for drug development.
  • Antimicrobial Activity: Research has indicated that compounds with similar hydrazone functionalities often exhibit antimicrobial properties. N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide may possess similar characteristics, leading to further exploration in antimicrobial research.
  • Structural Versatility: The presence of both benzyl and chlorobenzoyl groups in its structure enhances the compound’s versatility. Such features not only impact the reactivity but also open avenues for modifications that could yield new derivatives with distinct biological activities.
  • Hybridization and Bonding: The presence of hydrazino (-NH-NH-) and amide (-C(=O)NH-) functional groups reveals an interesting aspect of hybridization and bonding in the compound that may contribute to its stability and reactivity.
  • Structure-Activity Relationship (SAR): Investigating N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide can provide insights into the SAR, a fundamental concept in drug design where modifications in chemical structure directly correlate with biological activity.

In summary, N-benzyl-3-[2-(3-chlorobenzoyl)hydrazino]propanamide exemplifies the complexity and potential that hydrazone compounds hold in modern chemistry and pharmacology. As scientists continue to explore its properties, we may uncover even more applications that can significantly impact various fields.

Synonyms
P 1280
BRN 2168074
BENZOIC ACID, m-CHLORO-, 2-(2-(BENZYLCARBAMYOL)ETHYL)HYDRAZIDE
15563-24-3
m-Chlorobenzoic acid 2-(2-(benzylcarbamoyl)ethyl)hydrazide
DTXSID40165940
DTXCID3088431