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N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide

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Identification
Molecular formula
C17H17FN2O2
CAS number
523-07-1
IUPAC name
N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide
State
State

This compound is generally found in a solid state at room temperature.

Melting point (Celsius)
142.50
Melting point (Kelvin)
415.65
Boiling point (Celsius)
329.90
Boiling point (Kelvin)
603.05
General information
Molecular weight
286.33g/mol
Molar mass
286.3000g/mol
Density
1.2958g/cm3
Appearence

N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide is typically encountered as a crystalline solid. The exact color and texture can vary depending on the purity and specific formulation.

Comment on solubility

Solubility of N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide

N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide is a compound that exhibits intriguing solubility characteristics, primarily influenced by its unique molecular structure. The solubility is often affected by several factors, including:

  • Polarity: The presence of functional groups such as the hydrazino and amide groups can contribute to increased polarity, which affects its interaction with polar solvents.
  • Hydrogen bonding: The ability of this compound to form hydrogen bonds may enhance its solubility in protic solvents like water. This is crucial as hydrogen bond donors and acceptors play a significant role in solvation processes.
  • Solvent choice: This compound is more likely to dissolve in organic solvents like ethanol, methanol, or dimethyl sulfoxide (DMSO) compared to non-polar solvents due to its polar characteristics.

In general, one could summarize the solubility behavior as follows:

  1. Relatively soluble in polar solvents due to potential hydrogen bonding.
  2. Less soluble in non-polar solvents based on its structural properties.
  3. Practical applications may depend on enhancing solubility through appropriate solvent selection.

In conclusion, understanding the solubility of N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide is essential for its potential applications in pharmaceuticals and materials science. Careful consideration of solubility can lead to improved formulation strategies and enhanced biological efficacy.

Interesting facts

Interesting Facts about N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide

N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide is a fascinating compound that lies at the intersection of medicinal chemistry and pharmaceutical research. This compound has garnered attention for various reasons:

  • Pharmaceutical Potential: N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide may exhibit biological activities that could be pivotal in drug development, particularly in the treatment of cancer or infectious diseases.
  • Synthetic Versatility: The synthesis of this compound involves significant chemical transformations, showcasing the ingenuity required in organic synthesis. The hydrazine group is crucial for the formation of diverse derivative compounds.
  • Mechanistic Studies: Understanding the mechanism of action for compounds like N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide can lead to advances in targeted therapies. Researchers often study such compounds to identify their interactions at the molecular level.
  • Structure-Activity Relationship (SAR): The unique structural features of this compound provide insights into SAR. By modifying different components, scientists can systematically explore how changes affect biological activity.
  • Fluorine's Role: The presence of the fluorine atom in 4-fluorobenzoyl is of significant interest, as fluorine can enhance metabolic stability and bioavailability in pharmacological compounds.

As a valuable candidate for further studies, N-benzyl-3-[2-(4-fluorobenzoyl)hydrazino]propanamide embodies the complexity and promise of modern chemistry. As the famous chemist Linus Pauling once stated, "The best way to have a good idea is to have lots of ideas." This compound exemplifies the multitude of scientific inquiries that can stem from a single molecular structure.

Synonyms
P 1281
BRN 2167943
BENZOIC ACID, p-FLUORO-, 2-(2-(BENZYLCARBAMOYL)ETHYL)HYDRAZIDE
1479-89-6
p-Fluorobenzoic acid 2-(2-(benzylcarbamoyl)ethyl)hydrazide
DTXSID20163828
DTXCID8086319